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| 1 | Current knowledge on diabetic retinopathy from human donor tissues显示文摘According to the American Diabetes Association,diabetes was the seventh leading cause of death,and diabetic retinopathy the leading cause of blindness in working age adults in the United States in 2010.Diabetes is characterized by hyperglycemia associated with either hypoinsulinemia or insulin resistance,and over time,this chronic metabolic condition may lead to various complications including kidney failure,heart attacks,and retinal degeneration.In order to better understand the molecular basis of this disease and its complications,animal models have been the primary approach used to investigate the effects of diabetes on various tissues or cell types of the body,including the retina.However,inherent to these animal models are critical limitations that make the insight gained from these models challenging to apply to the human pathology.These difficulties in translating the knowledge obtained from animal studies have led a growing number of research groups to explore the diabetes complications,especially diabetic retinopathy,on tissues from human donors.This review summarizes the data collected from diabetic patients at various stages of diabetic retinopathy and classifies the data based upon their relevance to the main aspects of diabetic retinopathy:retinal vasculature dysfunction,inflammation,and neurodegeneration.This review discusses the importance of those studies to discriminate and establish the relevance of the findings obtained from animal models but also the limitations of such approaches. | Jessica H Eisma Jennifer E Dulle Patrice E Fort | 2015 | World Journal of Diabetes2015,6,2: | 19 |
| 2 | The Bedload Movement in the Changjiang Estuary显示文摘- Sandwaves in the Changjiang estuary were measured with a shallow sediment profiler and an echosounder from 1978 to 1988. The data, together with grain size and bedform of sediment indicates that the bedload movement by rolling and saltation is of great significance to sediment transport and is the principal factor responsible for sandwave and sandbody development in the estuary. The sandwaves were found well-developed, which is related to the tidal range and the velocity of ebb current. However, the further growth is restricted by strong flood current prevailing in the estuary. Because of the significant bedload, the sandbodies shift obviously and frequently, and sometimes the exchange of position occurs between the sandbodies and tidal channels. As a result, ships are regularly forced to change their navigation course. | Li Jiufa, Shi Weirong, Shen Huanting Xu Haigen and Doeke Eisma Associate Professor, Institute of Estuarine & Coastal Research (1ECR), East China Normal University, Shanghai200062 Professor, IECR, East China Normal University, Shanghai 200062 Professor, Netherlands Institute for Sea Research, P. O. Box 59 1790 AB, Den Burg, Texel, The Netherlands | 1993 | China Ocean Engineering1993,8,4: | 15 |
| 3 | ^(210)Pb沉积速率测定法在浅水动力环境中的应用显示文摘本文根据瓦登海(Waddensea)潮滩沉积物。^(210)Pb强度的测定和有关实验,讨论了^(210)Pb沉积速率测定法在浅水动力环境中应用所存在的一些问题和原因;提出了^(210)Pb“转换时间”和“沉降时间”概念;分析了泥沙运动与沉积物^(210)Pb强度的关系并依据粒度指标对某些不规则^(210)Pb剖面进行修正;发现Jade湾潮滩现代沉积速度为0.16—0.29cm/a,Greetsiel为0.16cm/a,Afsluitdfijk大坝附近达6.0cm/a,反映了大坝工程改变动力环境后出现的聚淤现象。 | 陈卫跃 沈健 D. Eisma G. W. Berger | 1990 | 海洋与湖沼1990,21,6: | 3 |
| 4 | Harmonious Development of Utilization and Protection of Tidal Flats and Wetlands-A Case Study in Shanghai Area显示文摘Spatial,environmental,and material resources are important for tidal flats and wetlands,thus,a harmonious balance between utilization and protection should be maintained.In the present study,the concept of tidal flat is defined,and its spatial limitation is also clarified.Located at the Yangtze Estuary,tidal flats in Shanghai area are selected for study.The relationship between water discharge and sediment transport of the Yangtze River,allowed exploration intensity and needs for wetland protection are discussed in the paper.The dynamic process and changing trend for different types of tidal flats are illustrated in detail.Regulations are proposed for a reasonable exploitation,dynamic protection,and ecosystem restoration of each individual tidal flat and wetland.Some valuable suggestions are put forward for further study about the sustainable exploitation of offshore resources in Shanghai area. | 陈吉余 程和琴 戴志军 Doeke EISMA | 2008 | China Ocean Engineering2008,22,4: | 3 |
| 5 | Transfer ming growth factor beta expression in otitis media with effusion显示文摘 | Cooter MS Eisma RJ Burleson JA | 1998 | Laryngoscope1998,108,: | 1 |
| 6 | Coexperssion of interleukin-8 recptor in head neck sequamous cell carcinoma 显示文摘 | Bryan L R Roselle J Eisma BS | 1997 | Am J Surg1997,174,: | 1 |
| 7 | Transforming growth factor-beta expression in otitis media with effusion显示文摘 | Cooter MS Eisma RJ Burleson JA | 1998 | Laryngoscope1998,108,: | 1 |
| 8 | A camera and image-analysis system for in situ observation of flocs in natural waters 显示文摘 | Eisma D Schuhmacher T Boekel H | 1990 | Netherlands Journal of Sea research1990,27,1: | 1 |
| 9 | Expression ofbasic fibroblast growth factor and its receptors by headand neck squamous carcinoma tumor and vascularendothelial cells 显示文摘 | Dellacono F R Spiro J Eisma R | 1997 | Am JSurg1997,174,5: | 1 |
| 10 | Interleukin-8 expression in human nasal polyps 显示文摘 | Allen JS Eisma R Leonard G | 1997 | Otolarygol Head Neck Surg1997,117,5: | 1 |
| 11 | A camera and image-analysis system for in situ observation of flocs in natural waters显示文摘 | Eisma D Schuhmacher T Boekel H | 1990 | Netherlands Journal of Sea Research1990,27,1: | 1 |
| 12 | Decreased expression of transforming growth factor beta receptors on head and neck squamous cell carcinoma tumor cells 显示文摘 | Eisma RJ Spiro JD yon Biberstein SE | 1996 | Am J Surg1996,172,6: | 1 |
| 13 | Vascular endothelial growth factor expression in head and neck squmous cell carcinoma显示文摘 | Eisma RJ Spiro JD Kreutzer DL | 1997 | Am J Surg1997,174,5: | 1 |
| 14 | Sedimentary processes on an estuarine marsh island within the turbidity maximum zone of the Yangtze River mouth 显示文摘 | Yang S L Eisma D Ding P X | 2000 | Geo-Marine Letters2000,20,: | 1 |
| 15 | Sedimentary processes on an estuarine marsh island within the turbidity maximum zone of the Yangtze River mouth 显示文摘 | Yang S L Eisma D Ding P X | 2000 | Geo-Mar Lett2000,20,2: | 1 |
| 16 | Interlenkin-8 expression human nasal polyps显示文摘 | Allen JS Eisma R Leenard C | 1997 | Otolaryngol Head Neck Surg1997,117,5: | 1 |
| 17 | Interferon gamma expression in human nasal polyps显示文摘 | Dellacono F R Eisma R Lafreniere D | 1997 | Laryngoscope1997,107,5: | 1 |
| 18 | Transforming growth factor-beta expression in otitis media with effusion显示文摘 | COOTER M S EISMA R J BURLESON J A | 1998 | Laryngoscope1998,108,6: | 1 |
| 19 | Determination of opal in marine sediments by X-ray diffraction显示文摘 | EISMA D VAN DER GAAST S J | 1971 | Netherlands Journal of Sea Research1971,5,: | 1 |
| 20 | Avoidance processes mediate the relationship between rumination and symptoms of complicated grief and depression following loss 显示文摘 | Eisma MC Stroebe MS Sehut HA | 2013 | J Abnorm Psycho2013,122,4: | 1 |