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| 1 | Serial intravenous doses of dezocine, morphine, and nalbuphine in the management of postoperative pain for outpatients 显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 3 |
| 2 | Cellular exposure to muscle relaxants and propofol could lead to genomic instabilityin vitro显示文摘Anesthesia is widely used in several medical settings and accepted as safe.However,there is some evidence that anesthetic agents can induce genomic changes leading to neural degeneration or apoptosis.Although chromosomal changes have not been observed in vivo,this is most likely due to DNA repair mechanisms,apoptosis,or cellular senescence.Potential chromosomal alterations after exposure to common anesthetic agents may be relevant in patients with genomic instability syndromes or with aggressive treatment of malignancies.In this study,the P388 murine B cells were cultured in vitro,and spectral karyotyping (SKY) was utilized to uncover genomewide changes.Clinically relevant doses of cisatracurium and propofol increased structural and numerical chromosomal instability.These results may be relevant in patients with underlying chromosomal instability syndromes or concurrently being exposed to chemotherapeutic agents.Future studies may include utilization of stimulated peripheral blood lymphocytes to further confirm the significance of these results. | Allen Edward Coleman Nicole McNeil Alexander Leonidovich Kovalchuck Dara Wangsa Thomas Ried Hong Wang | 2012 | The Journal of Biomedical Research2012，26，2： | 1 |
| 3 | Annual report to the nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment 显示文摘 | Edwards BK Brown ML Wingo PA Howe HL Ward E Ries LA | 2005 | J Natl Cancer Inst2005，97，19： | 1 |
| 4 | Serial intravenous doses of dezoeine,morphine,and nalbuphine in the management of postoperative pain for outpatients 显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 5 | Serial Intravenous Doses ofDezocine,Morphine,and Nalbuphine in the Management of PostoprativePain for Outpatients显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Aneth Analg1993，77，3： | 1 |
| 6 | The surveillance,epidemiology,and end results program a national resource显示文摘 | Hankey BF Ries LA Edwards BK | 1999 | Cancer Epidemiol Biomarkers Prev1999，8，12： | 1 |
| 7 | Serial in- travenous doses of dezocine, morphine, and nalbuphine in the management of postoperative pain for outpatients 显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 8 | Serial intra-venous doses of dezocine,morphine,and nalbuphine in the management of postoperative pain for outpatients显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 9 | Serial intravenous doses of dezocine,morphine and nalbuphine in the man- agement of postoperative pain for outpatiens 显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 10 | Serial in- travenous doses of dezocine, morphine and nalbuphine in the management of post-operative pain for outpa- tients显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 11 | Serial in- travenous doses of dezocine,morphine,and nalbuphine in the management of postoperative pain for outpatients 显示文摘 | COHEN RI EDWARDS WT KEZER EA | 1993 | Anesth Analg1993，，： | 1 |
| 12 | Serial intravenous doses of dezo-cine,morphine,and nalbuphine in the management of postoperative pain for outpatients显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 13 | Intravenousdoses of dezo- cine,morphine, and nalbuphine in the man-agement of postoperative pain for outpatients 显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | AnesthAnalg1993，，77： | 1 |
| 14 | Serial Intravenous Doses of Dezocine, Morphine, and Nalhuphine in the Management of Postoperative Pain for Outpatients 显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，53： | 1 |
| 15 | Serial intravenous doses of dezocine, morphine, and nalbuphine in the man- agement of postoperative pain for outpatients显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 16 | Serial intravenous doses of dezocine, morphine, and nalbuphine in the management ofpostoperative pain for outpatients 显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 17 | Intravenous doses of Dezocine, morphine, and nalbuphine in the manage- ment of Postoperative pain for outpatients显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 18 | Serial intravenous dosesof dezocine,morphine,and nalbuphine in the management of post-operative pain for outpatients显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
| 19 | Serial intravenous doses of dezocine,morphine,and nalbuphine in the management of postoperative pain for outpatients显示文摘 | Cohen RI Edwards WT Kezer EA | | 0，，03： | 1 |
| 20 | Serial intravenous doses of dezocine,morphine and nalbuphine in the management of postoperative pain for outpatients显示文摘 | Cohen RI Edwards WT Kezer EA | 1993 | Anesth Analg1993，77，3： | 1 |
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