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| 1 | Severe cyclophosphamide-related hyponatremia in a patient with acute glomerulonephritis显示文摘Cyclophosphamide is frequently used to treat cancer,autoimmune and renal diseases,such as rapidly progressive glomerulonephritis.Its side effects are well-known,including bone marrow depression,infections,alopecia,sterility,bladder malignancy and hemorrhagic cystitis.Moreover,in some cases cyclophosphamide use has been related to the onset of hyponatremia,by development of a syndrome of inappropriate antidiuresis.Indeed,severe hyponatremia has been previously reported in patients treated with high-dose or moderate-dose of intravenous cyclophosphamide,while only few cases have been reported in patients treated with low dose.Here,we discuss a case of a syndrome of inappropriate antidiuresis followed to a single low-dose of intravenous cyclophosphamide in a patient with a histological diagnosis of acute glomerulonephritis,presenting as acute kidney injury.After cyclophosphamide administration(500 mg IV),while renal function gradually improved,the patient developed confusion and headache.Laboratory examinations showed serum sodium concentration dropped to 122 mmol per liter associated with an elevated urinary osmolality of 199 mO sm/kg,while common causes of acute hyponatremia were excluded.He was successfully treated with water restriction and hypertonic saline solution infusion with the resolution of the electrolyte disorder.This case,together with the previous ones already reported,highlights that electrolyte profile should be strictly monitored in patients undergoing cyclophosphamide therapy in order to early recognize the potentially lifethreatening complications of acute water retention. | Pasquale Esposito Maria Valentina Domenech Nicoletta Serpieri Marta Calatroni Ilaria Massa Alessandro Avella Edoardo La Porta Luca Estienne Elena Caramella Teresa Rampino | 2017 | World Journal of Nephrology2017，6，4： | 2 |
| 2 | Modulation of growth hormone, luteinizing hormone,and testosterone secretion by excitatory amino acids in boars显示文摘 | ESTIENNE M J BARB C R | 2002 | Reprod Biol2002，2，1： | 1 |
| 3 | Multicenter study on TGPO autoantibody prevalence in various thyroid and non-thyroid diseases; relationships with thyroglobulin and thyroperoxidase autoantibody parameters显示文摘 | Estienne V Duthoit C Costanzo VD | 1999 | Eur J Endocrinol 1999 Dec1999，141，6： | 1 |
| 4 | The control of adenohypophysial hormone secretion by amino acids and peptides in swine显示文摘 | Estienne M J Barb C R | 2005 | Domest Anim Endocrinol2005，29，1： | 1 |
| 5 | Lattice Constants of K-and Mg-doped LiNbO3 Comparison with Nonstoichiometric Lithium Niobate 显示文摘 | Cerclier O Estienne J | 1995 | Journal of Physics and Chemistry of Solids1995，56，： | 1 |
| 6 | Complement activation by direct C4 binding to thyroperoxidase in Hashimoto's thyroiditis显示文摘 | Blanchin S Estienne V Durand-Gorde J M | 2003 | Endocrinology2003，144，12： | 1 |
| 7 | Dietary supplementation with a source of omega-3 fatty acids increases sperm number and the duration of ejaculation in boars显示文摘 | M.J. Estienne A.F. Harper R.J. Crawford | 2008 | Theriogenology2008，，1： | 1 |
| 8 | Serum concentrations of luteinizing hormone, growth hormone, and cortisol in gilts treated with N-methyl-D, L-aspartate during the estrous cycle or after ovariectomy显示文摘 | Estienne M J Hurlock W F Barb C R | 1998 | J Anim Sci1998，76，： | 1 |
| 9 | N-methyl-D, L-as-partic-induced growth hormone secretion in barrows: possible mechanisms of action显示文摘 | Estienne Harter-Dennis Barb | 1996 | J Anim Sci1996，74，： | 1 |
| 10 | Evidence that the complement control protein-epidermal growth factor-like domain of thyroid peroxidase lies on the fringe of the immunodominant region recognized by autoantibodies显示文摘 | Pichurin P N Guo J Estienne V | 2002 | Thyroid2002，12，12： | 1 |
| 11 | A Comparison of Multivariate Calibra- tion Techniques Applied to Experimental NIR Data Sets: Part III: Robustness against Instrumental Per- turbation Conditions 显示文摘 | Estienne F | 2004 | Chemometrics and Intelli- ~ent Laboratory Systems2004，29，73： | 1 |
| 12 | Growth performance and intestinal morphologu re- sponses in early weaned pigs to supplementation ofantibiotic-free diets with an organic copper complex and spray-dried plasma protein in sanitary and nonsanitary environments 显示文摘 | ZHAO J HARPER M J ESTIENNE M J | 2007 | Journal of Animal Science2007，85，： | 1 |
| 13 | Multivariate calibration with Raman spectroscopic data: a case study 显示文摘 | Estienne F Massart D L Zanier-Szydlowski N | 2000 | Analytica ChirnicaActa2000，424，2： | 1 |
| 14 | Mutlivariate calibration with Raman data using fast princip component regression and partial least squares methods 显示文摘 | Estienne F Massart D L | 2001 | Analytica Chimica Acta2001，450，12： | 1 |
| 15 | Efficacy of the potential alternatives to antimicrobial feed additives for weanling pigs显示文摘 | Harper A F M J Estienne | 2002 | Prof Animal Scientist2002，18，： | 1 |
| 16 | Semen characteristics and libido in boars treated repeatedly with PGF2tx 显示文摘 | ESTIENNE M J HARPER A F | 2004 | Journal of Animal Science2004，82，5： | 1 |
| 17 | Growth performance and intestinal morphologu responses in early weaned pigs to supplementation of antibiotic-free diets with an organic copper complex and spray-dried plasma protein in sanitary and nonsanitary environments显示文摘 | ZHAO J HARPER M J ESTIENNE M J | 2007 | Journal of Animal Science2007，85，： | 1 |
| 18 | Dietary supplementa- tion with a source of omega-3 fatty acids increases sperm number and the duration of ejaculation in boars显示文摘 | Estienne M J Harper A F Beal W E | 2008 | Theriogenology2008，70，1： | 1 |
| 19 | Effect of naloxone treatment on luteinizing hormone and testosterone concentrations in boars with high and low libido 显示文摘 | ESTIENNE M J HARPER A F SPEIGHT S M | 2009 | Reproductive Biology2009，9，3： | 1 |
| 20 | Proposed Realization of the Dicke-model Quantum Phase Transition in an Optical Cavity QED System 显示文摘 | Dimer F Estienne B Parkins A S | 2007 | Phys Rev A2007，75，01： | 1 |
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