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| 1 | Circulating tumor DNA as a liquid biopsy target for detection of pancreatic cancer显示文摘Most pancreatic cancer patients present with advanced metastatic disease, resulting in extremely poor 5-year survival, mainly because of the lack of a reliable modality for early detection and limited therapeutic options for advanced disease. Therefore, there is a need for minimally-invasive diagnostic tools for detecting pancreatic cancer at an early stage, when curative surgery and also novel therapeutic approaches including precision medicine may be feasible. The 'liquid biopsy' addresses these unmet clinical needs based on the concept that simple peripheral blood sampling and detection of circulating tumor DNA(ct DNA) could provide diagnostic information. In this review, we provide an overview of the current status of bloodbased tests for diagnosis of pancreatic cancer and the potential utility of ct DNA for precision medicine. We also discuss challenges that remain to be addressed in developing practical ct DNA-based liquid biopsy approaches for early diagnosis of pancreatic cancer. | Erina Takai Shinichi Yachida | 2016 | World Journal of Gastroenterology2016，22，38： | 8 |
| 2 | Genomic alterations in pancreatic cancer and their relevance to therapy显示文摘Pancreatic cancer is a highly lethal cancer type, for which there are few viable therapeutic options. But, with the advance of sequencing technologies for global genomic analysis, the landscape of genomic alterations in pancreatic cancer is becoming increasingly well understood. In this review, we summarize current knowledge of genomic alterations in 12 core signaling pathways or cellular processes in pancreatic ductal adenocarcinoma, which is the most common type of malignancy in the pancreas, including four commonly mutated genes and many other genes that are mutated at low frequencies. We also describe the potential implications of these genomic alterations for development of novel therapeutic approaches in the context of personalized medicine. | Erina Takai Shinichi Yachida | 2015 | World Journal of Gastrointestinal Oncology2015，7，10： | 2 |
| 3 | Effects of blend composition and dynamic vulcanization on the morphology and dynamic viscoelastic properties of PP/ EPDM blends 显示文摘 | Prut E V Erina N A Karger-Kocsis J | 2008 | J Appl Polym Sci2008，109，2： | 1 |
| 4 | Eddy convection in coaxial supersonic jets显示文摘 | Erina Murakami Dimitri Papamoschou | 2000 | AIAA journal2000，38，4： | 1 |
| 5 | The metabolic state of cancer stem cells—a valid target for cancer therapy?显示文摘 | Erina Vlashi Frank Pajonk | 2014 | Free Radical Biology and Medicine2014，，： | 1 |
| 6 | Partial male sterility in transgenic tobacco carrying an antisense gene for alternative oxidase under the control of a tapetum-specific promoter显示文摘 | Hiroyasu Kitashiba Erina Kitazawa Sachie Kishitani Kinya Toriyama | 1999 | Molecular Breeding1999，，3： | 1 |
| 7 | Endocrinological outcomes of pure endoscopic transsphenoidal surgery:a Croatian Referral Pituitary Center experience显示文摘 | Mari(c) A Kruljac I (C)erina V | 2012 | Croat Med J2012，53，3： | 1 |
| 8 | Bluetooth and Wi-Fi Wireless Protocols:A Survey and a Comparison显示文摘 | Erina Ferro Francesco Potorti | 2005 | IEEE Wireless Communications2005，12，1： | 1 |
| 9 | Endocrinological outcomes of pure endoscopic transsphenoidal surgery:a Croatian Referral Pitui- tary Center experience显示文摘 | Marie A Kruljac I erina V | 2012 | Croat Med J2012，53，3： | 1 |
| 10 | Enteral supplement enriched with glutamine, fiber and oligosaccharide attenuates experimental colitis in mice 显示文摘 | Erina Joo M S Shunsuke Yamane M D | 2013 | Nutrition2013，12，3： | 1 |
| 11 | Effectof joint action of high pressure and shear deformationon mechanical degradation of isotactic polypropylene显示文摘 | KOMPANIETS L V KUPTSOV S A ERINA N A | 2004 | Polymer Degradation and Stability2004，84，： | 1 |
| 12 | Effects of blendcomposition and dynamic vulcanization on the morphology anddynamic viscoelastic properties of PP/EPDM blends显示文摘 | Prut E V Erina N A Karger-Kocsis J | 2008 | J Ap-pl Poly Sci2008，109，2： | 1 |
| 13 | A new 3-axis magnetic field measurement system based Hall elements 显示文摘 | Erina H | 2004 | IEEE Transactions on Applied Superconductivity2004，14，2： | 1 |
| 14 | Female sex hormones ameliorate arthritis in SKG mice显示文摘 | Kazuki I Erina I Yuuki I | 2013 | Biochem Biophys Res Commun2013，434，4： | 1 |
| 15 | Gender Differences in Attributions and Emotions in Helping Contexts显示文摘 | Erina L. MacGeorge | 2003 | Sex Roles (-)2003，，3： | 1 |
| 16 | A new 3-axis magnetic field measurement system based on Hall elements 显示文摘 | ERINA H | 2004 | IEEE Transactions on Applied Superconductivity2004，14，2： | 1 |
| 17 | Radiation-induced reprograming of breast cancer cells显示文摘 | Charm L Erina V Lorenza DD | 2012 | Stem Cells2012，，30： | 1 |
| 18 | Serum thrombopoietin levels in patients with chronic hepatitis and liver cirrhosis显示文摘 | Tsunehisa Kawasaki Akihiro Takeshita Kenichi Souda Yoshimasa Kobayashi Masataka Kikuyama Fumitaka Suzuki Fujito Kageyama Yuzou Sasada Erina Shimizu Gou Murohisa Shigeki Koide Teruya Yoshimi Hirotoshi Nakamura Ryuzo Ohno | 1999 | The American Journal of Gastroenterology1999，，7： | 1 |
| 19 | Assessment of Higher Education Finan- cing Models in the CEE Countries 显示文摘 | Jana Erina Ingars Erins | 2014 | Procedia2014，，7： | 1 |
| 20 | Extension of size of monodisperse silica nanospheres and their well-ordered assembly显示文摘 | Ryota Watanabe Toshiyuki Yokoi Erina Kobayashi | 2011 | Journal of Colloid and Interface Science2011，360，1： | 1 |
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