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| 1 | Cyclooxygenase-2 and epithelial growth factor receptor up-regulation during progression of Barrett's esophagus to adenocarcinoma显示文摘瞄准:在整个 Barretts 食管的前进调查 cyclooxygenase-2 (COX-2 ) 和上皮的生长因素受体(EGFR ) 的表示() 。方法:COX-2 和 EGFR 蛋白质表情被使用免疫检测组织化学的方法。详细 cytomorphological 改变的 A 是坚定的。COX-2 和 EGFR 表示的区域被使用计算机成像系统确定。结果:COX-2 和 EGFR 的表情与前进一起增加了从到食管腺癌(EAC ) 。积极关联在 COX-2 表示和 EGFR 表示之间被发现。结论:COX-2 和 EGFR 可能在逐步的前进从是合作的到 EAC,从而导致致癌作用。 | Yan Li John M Wo Mukunda B Ray Whitney Jones Ruifeng R Su Susan Ellis Robert C G Martin | 2006 | World Journal of Gastroenterology2006，12，6： | 14 |
| 2 | 华南丘陵区村级景观下土地利用/土地覆盖对土壤质量的影响显示文摘利用IKONOS高分辨率(1m)卫星遥感图,根据Ellis提出的村级景观分类体系,研究华南丘陵区村级景观中的土壤容重、土壤有机质、土壤全氮和土壤全磷的含量和分布特征。结果表明:不同土地利用景观中,表层土壤(0~15cm)的土壤容重、有机质和全氮均有显著差异,最大值分别为:1.42gcm^-3(建设用地)、18.67g kg^-1(水田)和0.95g kg^-1(水田),而全磷差异不显著。由于林地面积最大,其土壤养分储量也最大,表层土壤有机质、全氮、全磷储量分别占整个地区表层总储量的55.05%、53.88%、46.23%。不同土地覆盖景观中,表层土壤的土壤容重、有机质、全氮也都有显著差异,最大值分别为:1.42gcm^-3(硬化地面)、15.96g kg^-1(混合植被)和0.68g kg^-1(混合植被),而全磷差异也不显著。多年生植被在土地覆盖景观中所占面积最大,其表层土壤有机质、全氮、全磷储量分别占整个地区表层总储量的55.01%、54.53%、59.02%。由于下层受人为干扰较小,不论是在不同土地利用方式还是在土地覆盖下,下层土壤(15~30cm)的土壤容重、有机质、全氮和全磷均无显著差异。人为强烈干扰下,植被覆盖度低的交通用地、房屋及其附近的干扰地和荒地与植被覆盖度高的林地、水田相比较,土壤容重高,而土壤有机质、土壤全氮和土壤全磷含量低。 | 焦加国 武俊喜 李辉信 杨林章 肖红生 Erle C Ellis | 2007 | 土壤学报2007，44，2： | 13 |
| 3 | 长江平原区乡村景观的结构、管理及其对土壤氮磷的影响显示文摘通过实地研究主要位于宜兴市域的区域乡村景观代表性样方,评价并阐明了人口密集的长江平原区乡村景观的结构、管理与土壤全氮、全磷密度和储量的关系。景观绘图是基于1m分辨率的IKONOS影像并采用生态立地分类及绘图标准,通过直接解译和实地检验对均质景观缀块进行分类和绘图;依据区域权重分层取样方法,在生态立地缀块中随机设定取样点进行土壤或底泥取样;通过自助法对12个样方重取样,用区域多变量最优化方法计算样方的区域权重,并结合不确定性分析模型评价区域土地利用/覆被、土壤全氮和全磷储量。结果表明:在85.24×10^3km^2的长江平原区乡村景观面积范围内,0—30cm土壤全氮、全磷储量分别为29.87TgN和19.79TgP。最大的5种土地利用/覆被的类型为水田、水产养殖、非渗漏性建筑用地、旱地1年生作物和闲置水域,占区域总面积的82.9%;其土壤全氮、全磷储量分别占区域总量的82.6%和80.8%。其中平原稻田面积为38.93×10^3km^2,占总面积的45.5%;其0—30cm土壤全氮、全磷储量分别高达15.26TgN和9.13TgP,分别占总储量的51%和45%。揭示了人口密集的乡村景观中土地利用/覆被方式对区域土壤全氮、全磷的影响模式。这种在小尺度下对土地管理调查,土壤全氮、全磷及其它生态特征研究方法的精确度明显优于传统的基于30~1000m分辨率遥感影像的土地覆被研究。 | 武俊喜 焦加国 肖红生 王洪庆 杨林章 程序 Ellis Eele C | 2008 | 生态学报2008，28，8： | 4 |
| 4 | 1940-2002年长江中下游平原乡村景观区域中耕地类型及其土壤氮磷储量的变化显示文摘过去60a间,长江中下游平原乡村景观区域中土地利用覆被类型,特别是耕地类型发生了显著地转变,并对其土壤全氮和全磷产生了明显地影响。通过选取区域代表性样方、研究耕地类型的小尺度转化、土壤取样和收集1965年前土壤全氮、全磷历史数据,采用尺度推绎和蒙特卡洛不确定性分析方法,评价了1940-2002年长江中下游平原人口密集的乡村景观区域中耕地类型及其土壤全氮、全磷储量的变化。结果表明:近60a来,在86×103km2的区域中有47%的面积发生了变化,其中33%的面积是耕地类型转化。耕地面积减少18.6%(-16.0×103km2),其中稻田面积减少21.5%(-18.5×103km2),种植木本作物的旱地面积减少1.7%(-1.5×103km2);而种植木本作物和种植1年生作物的水浇地的面积分别增加了3.5%(3.0×103km2)和2.0%(1.7×103km2)。尽管稻田面积大幅减少,但其仍是区域中面积最大的土地利用覆被类型。1940-2002年,有98%的可能性区域耕地0-30cm土壤全氮储量净减少,而其0-30cm土壤全磷储量则无明显变化。区域耕地土壤全氮储量明显减少(-7.2Tg N),主要受稻田土壤全氮储量显著减少(-8.0Tg N)的影响,而稻田面积大幅减少是导致稻田土壤全氮储量减少的主要原因。与此同时,种植木本作物的旱地的土壤全氮储量减少了0.7Tg N;而种植木本作物和种植1年生作物的水浇地分别增加1.3和0.7Tg N。区域耕地土壤全磷储量变化不明显,主要受稻田土壤全磷储量无明显变化的影响。尽管稻田面积大幅减少,但由于稻田土壤全磷密度增加了29%(其净增加的可能性为76%);加之稻田土壤全磷密度变异较大,所以稻田土壤全磷储量并没有明显减少,其净减少的可能性仅为64%。与此同时,有75%的可能性种植木本作物的旱地的土壤全磷储量净减少,但仅减少了0.3Tg P;而种植木本作物的水浇地和种植1年生作物的水浇地土壤全磷都有少量增加,分别为0.7和0.4Tg P。通过选取区域代表性样方、研究耕地类型的小尺度转化、土壤取样和收集土壤历史数据、结合尺度推绎和蒙特卡洛不确定性分析方法,能够揭示1940-2002年长江中下游平原人口密集的乡村景观区域中耕地类型及其土壤全氮和全磷储量的变化。 | 武俊喜 程序 焦加国 肖红生 杨林章 王洪庆 张福锁 Ellis Erle C | 2010 | 生态学报2010，30，23： | 4 |
| 5 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 6 | Formation of micronuclei in erythrocytes of the fathead minnow (Pimcphales promelas) after acute treatment with mitomycin C or cyclophosphamide 显示文摘 | WINTER M J ELLIS L C HUTCHINSON T H | 2007 | Mut Res2007，629，2： | 1 |
| 7 | First-line systemic chemotherapy in the treatment of advanced non-small cell lung cancer a systematic 显示文摘 | Goffin J Lacchetti C Ellis PM Ung YC Evans WK | 2010 | J Thoracic Oncol2010，5，2： | 1 |
| 8 | Cognitive perspectives on SL4 : The associative -cognitive CREED 显示文摘 | Ellis N C | 2006 | AILA Review2006，19，： | 1 |
| 9 | Hyperphosphorylated neurofilament NF-H is a serum biomarker of axonal injury显示文摘 | Shaw G Yang C Ellis R | 2005 | Biochem Biophys Res Commun2005，336，4： | 1 |
| 10 | Impact of a national external quality assessment scheme for breast pathology in the UK显示文摘 | Ellis IO Coleman D Wells C | 2006 | Clin Pathol2006，59，2： | 1 |
| 11 | Protein complexes mediate signalling in plant responses to hormones, light, sucrose and pathogens 显示文摘 | Ellis C Turner J G Devoto A | 2002 | Plant Mol Biol2002，50，6： | 1 |
| 12 | Mandibular motion after closed and open treatment of unilateral mandibular condylar process fractures 显示文摘 | Palmieri C Ellis E 3rd Throckmorton G | 1999 | J Oral Maxillofac Surg1999，57，7： | 1 |
| 13 | Association of genetic variation in the natriureAtrial natriuretic peptide in patients with cardiovascular outcomes显示文摘 | Ellis K L Newton-Cheh C Wang T J | 2011 | J Mol Ce(I Cardiol2011，50，4： | 1 |
| 14 | Characterization of chemical properties and flow parameters of powdered phenolformaldehyde resins 显示文摘 | Simon C Ellis Paul R Steiner | 1991 | Wood and Fiber Science1991，23，1： | 1 |
| 15 | Letrozole in the neoadjuvant setting: the P024 trial 显示文摘 | Ellis MJ Ma C | 2007 | Breast Cancer Res Treat2007，105，1： | 1 |
| 16 | psoriasis-recent advances in understanding its pathogenesis and treatment显示文摘 | Kruemer G Ellis S C N | 2005 | J Am Acad Dermatol2005，53，： | 1 |
| 17 | Sequence of protein disulphide isomerase and implications of its relationship to thioredoxin 显示文摘 | Edman J C Ellis L Blacher R W | 1985 | Nature1985，317，6034： | 1 |
| 18 | Hyperphosphorylated neu-rofilament NF-H is a serum biomarker of axonal injury显示文摘 | Sham G Yang C Ellis R | 2005 | Biochem Biophys Res Commum2005，336，： | 1 |
| 19 | Sequence data suggests big liver and spleen disease virus (BLSV) is genetically related to hepatitis E virus 显示文摘 | Payne C J Ellis T M Plant S L | 1999 | Veterinary Microbiology1999，68，： | 1 |
| 20 | The origin of large local uplift in extensional regions显示文摘 | King G C P Ellis S | 1990 | Nature1990，348，： | 1 |
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