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81篇 您的检索式:作者名="EHTESHAM M"
    题名 作者 年代 出处 被引量
1Intratumoral dendritic cell vaccin ation elicits potent tumoricidal im munity against malignant glioma in rats显示文摘Dendritic cells(DC)are attractive candidates for innovative cancer immunotherapy by virtu e of their ability to function as powe rful antigen presenting cells and elicit potent antitumor cytotoxic immune r esponses.With the aim of generating antitumor immunity,the authors sought to enhance in vivo tum or antigen presentation by using an i ntratumoral DC vaccination strateg y in the setting of partially irradiated intracranial brain tumo rs.Fisher rats,implanted with 9L gliomas in the right corpus striatum,w ere treated with freshly cultured,unpulsed syngeneic DC inoculated directly into the tumor bed.Intracranially inoculated DCs were found to drain to ipsilateral deep cervical lymph nodes.This was a ssociated with increased local and s ystemic antitumor cytoxicity,as evidenced by robust infiltration of treated tumors with CD4and CD8T ce lls as well as by increased IFN-gamma protein and message levels in in vitr o restimulated splenic lymphocytes.DC therapy resulted in prolonged survival and immunity to s ubsequent intracranial tumor re-ch allenge.These results demonstrate the viability of intratumoral DC vaccination as an effectiv e therapeutic strategy for intracra nial glioma.Ehtesham M Kabos P Gutierrez MA Samoto K Black KL Yu JS 2003癌症2003,22,7:8
2CXCR4 mediates the proliferation of glioblastoma progenitor cells 显示文摘Ehtesham M Mapara K Y Stevenson C B 2009Cancer Lett2009,274,2:1
3The use of Interleukin 12-secreting neural stem cells for the treatment of intracranial gliomas 显示文摘Ehtesham M Kabos P Kabosova A 2002Cancer Res2002,62,20:1
4Treatment of intracranial glioma with in situ interferon-gamma and tumor necrosis factor-alpha gene transfer 显示文摘Ehtesham M Samoto K Kabos P 2002Cancer Gene Ther2002,9,11:1
5Prognostic indicators of childhood acute viral encephalitis显示文摘Bhutto E Naim M Ehtesham M 1999J Pak Med Assoc1999,49,12:1
6Intratumoral T cell subset ratios and Fas ligand expression on brain tumor endothelium 显示文摘Yu JS Lee PK Ehtesham M 2003J Neurooncol2003,64,:1
7Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR41 显示文摘Ehtesham M Yuan X Kabos P 2004Neoplasia2004,6,3:1
8The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma显示文摘 KABOS P KABOSOVA A 2002Cancer Res2002,62,20:1
9Induction of glioblastoma apoptosis using neural stem cell-mediated delivery of tumor necrosis factor-related apoptosis-inducing ligand 显示文摘Ehtesham M Kabos P Gutierrez MA 2002Cancer Res2002,62,24:1
10Prognostic indicators of chiIdhood acute viral encephalitis显示文摘Bhutto E Naim M Ehtesham M 1999J Pak Med Assoc1999,49,12:1
11Generation of neural progenitor cells from whole adult bone marrow显示文摘Kabos P Ehtesham M Kabosova A 2002Exp Neurol2002,178,2:1
12Prognositic indicators of child-hood acute viral encephalitis显示文摘Bhutto E Naim M Ehtesham M 1999J Pak Med Assoc1999,49,12:1
13Prognositic indicators of child- hood acute viral encephalitis 显示文摘Bhutto E Naim M Ehtesham M 1999J Pak Med Assoc1999,49,12:1
14Prognostic indicators of childhood acute viral encephalitis显示文摘Bhutto E Naim M Ehtesham M 1999J Pak Med Assoc1999,49,12:1
15Prognostic indicators of childhood acute viral encephalitis显示文摘Bhutto E Naim M Ehtesham M 1999J Pak Med Assoc1999,49,12:1
16Prognostic indicators of child- hood acute viral encephalitis 显示文摘Bhutto E Naim M Ehtesham M 1999J Pak Med Assoc1999,49,12:1
17Ligand dependent activation of the hedgehog pathway in gliomaprogenitor cells 显示文摘Ehtesham M Sarangi A Valadez JG 2007Oncogene2007,26,39:1
18The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma显示文摘 KABOS P 2002Cancer Res2002,62,20:1
19Generation of Neural Progenitor Cells from Whole Adult Bone Marrow显示文摘Kabos P Ehtesham M Kabosova A 2002Experimental Neurology2002,178,2:1
20Recent progress in immunotherapy for malignant glioma:treatment strategies and results from clinical trials显示文摘Ehtesham M Black KL Yu JS 2004Cancer Control2004,11,3:1
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