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    题名 作者 年代 出处 被引量
1高速加工发展概况显示文摘本文全面介绍了高速加工的基础理论及发展过程 ,并对高速加工的优点和特性、高速加工的安全性、高速主轴及机床部件的发展从整体上进行了深入的讨论。同时 ,作者对发展高速加工需要的关键技术提出了研究方向 。Dr·-Ing·H·舒尔茨 王志刚 武凯 何宁 2002机械制造与自动化2002,,1:43
2全球听力障碍的现状及对策——WHO关于听障问题的白皮书简介显示文摘Dr Andrew Smith 王树峰 2004中国听力语言康复科学杂志2004,,6:24
3The expression and clinical significance of CD44v in human gastric cancers显示文摘INTRODUCTIONCD44 was originally implicated as a'homing'receptor directing the migration of recirculatinglymphocytes.CD44 expression has beenconfirmed not only in lymphocytes but also in awide variety of epithelial tissues.It is considered asan important cell adhesion molecule for cell to cellinteractions.Molecular cloning and analysisChen GY Wang DR 2000World Journal of Gastroenterology2000,6,1:22
4Hepatic angiomyolipoma-misdiagnosis as hepatocellular carcinoma:A report of 14 cases显示文摘INTRODUCTIONAngiomyolipoma(AML)is a rare benign mesenchymaltumor of the liver,composed of a varying heterogeneousmixture of three tissue components:blood vessels。Zhong DR Ji XL 2000World Journal of Gastroenterology2000,6,4:16
5203例农村有偿献血感染HIV患者抑郁障碍及生活质量调查显示文摘目的:调查通过献血途径感染人类免疫缺陷病毒(HIV)的203例患者的情绪状况及生活质量。方法:采用贝克抑郁问卷、复合性国际诊断用检查提纲和SF-36对203例通过献血途径感染HIV的患者(HIV阳性组)及年龄、性别和受教育年限相匹配的198例HIV阴性献血者进行调查。结果:①HIV阳性组献血次数多于HIV阴性组(52.2±95.4/13.2±23.9,P<0.001),已婚者少于HIV阴性组(88.6%/ 95.5%,P=0.020),丧偶者多于HIV阴性组(10.9%/4.5%,P=0.020),失业率高于HIV阴性组(21.7%/4.0%,P<0.001),前一年全年工作时间少于HIV阴性组(5.0±3.5/7.5±3.0,P<0.001),家庭月收入低于HIV阴性组(476.3±412.7/709.9±513.7,P<0.001)。②HIV阳性组被诊断为获得性免疫缺陷综合征(AIDS)者占56.6%。HIV阳性组抑郁症的终生患病率为13.8%,HIV阴性组的终生患病率为5.1%。HIV阳性组的抑郁总分(11.3±11.3/6.6±9.6)、躯体(3.3±2.9/2.0±2.6)和非躯体因子分(8.0±8.8/4.6±7.4)均高于HIV阴性组(P<0.001)。HIV阳性组达轻度抑郁以上者占40.4%。HIV阳性组已制定自杀计划者高于HIV阴性组(8.4%/3.0%,P<0.05)。HIV阳性组总体生理健康(48.3±9.7/ 55.5±7.0)和心理健康(48.8±8.9/55.1±7.8)得分均低于HIV阴性组(P<0.001)。③HIV阳性组的贝克抑郁问卷总分与T细胞亚群CD4细胞计数无显著相关,与总体生理健康及心理健康呈显著负相关(r=- 0.46~0.68,P<0.001)。结论:HIV阳性患者生存状况较差。对HIV阳性感染者而言,抑郁给患者生活质量造成全面的影响,抑郁和自杀风险仍然是需要干预和处理的问题。宁南义 石川 于欣 陈玉芳 吴尊友 Jin Hua Vigil O Cysique LA Franklin DR Grant I Heaton RK 2008中国心理卫生杂志2008,22,7:14
6概念验证演示:脑控制的肌肉刺激对恢复四肢瘫患者及物及抓握能力显示文摘高位颈脊髓损伤(SCI)患者难以完成日常生活所需的及物和抓握动作。本研究探讨了皮质脑机接口能够充分识别皮质信号以指挥功能性电刺激器(FES)进行手臂运动的能力。受试者是一名53岁的男性,C4,A级的脊髓损伤患者。将两个96通道微电极阵列植入控制手部区域的中央回运动皮层。患者练习一个三维虚拟手臂的运动四个月,然后增加36个经皮肌肉刺激电极于右臂。这些装置用来恢复手指和拇指,手腕,肘和肩的运动。然后对受试者进行皮质指令,张长杰 Ajiboye AB Willett FR Young DR 2017中国康复2017,32,4:11
7Primary 4-3-oxosteroid 5β-reductase deficiency:Two cases in China显示文摘Aldo-keto reductase 1D1(AKR1D1) deficiency,a rare but life-threatening form of bile acid deficiency,has not been previously described in China.Here,we describe the first two primary 4-3-oxosteroid 5β-reductase deficiency patients in China's Mainland diagnosed by fast atom bombardment-mass spectroscopy of urinary bile acids and confirmed by genetic analysis.A high proportion of atypical 3-oxo-4-bile acids in the urine indicated a deficiency in 4-3-oxosteroid 5β-reductase.All of the coding exons and adjacent intronic sequence of the AKR1D1 gene were sequenced using peripheral lymphocyte genomic DNA of two patients and one of the patient's parents.One patient exhibited compound heterozygous mutations:c.396C>A and c.722A>T,while the other was heterozygous for the mutation c.797G>A.Based on these mutations,a diagnosis of primary 4-3-oxosteroid 5β-reductase deficiency could be confirmed.With ursodeoxycholic acid treatment and fat-soluble vitamin supplements,liver function tests normalized rapidly,and the degree of hepatomegaly was markedly reduced in both patients.Jing Zhao Ling-Juan Fang Kenneth DR Setchell Rui Chen Li-Ting Li Jian-She Wang 2012World Journal of Gastroenterology2012,18,47:9
8Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca2+ transients and contraction in cardiomyocytes derived from embryonic stem cells显示文摘Fu JD Li J Tweedie D Yu HM Chen L Wang R Riordon DR Brugh SA Wang SQ Boheler KR Yang HT 2006中国生物学文摘2006,20,7:9
9Combined Chemical and Mineralogical Evidence for Heavy Metal Binding in Mining- and Smelting-Affected Alluvial Soils显示文摘The binding of metallic contaminants (Pb, Cd, and Zn) and As on soil constituents was studied on four highly con-taminated alluvial soil profiles from the mining/smelting district of Píbram (Czech Republic) using a combination of mineralogical and chemical methods. Sequential extraction analysis (SEA) was supplemented by mineralogical investi-gation of both bulk samples and heavy mineral fractions using X-ray diffraction analysis (XRD) and scanning electron microscopy with an energy dispersive X-ray spectrometer (SEM/EDS). The mineralogy of Fe and Mn oxides was studied by voltammetry of microparticles (VMP) and diffuse reflectance spectrometry (DRS). Zinc and Pb were predominantly bound in the reducible fraction attributed to Fe oxides and Mn oxides (mainly birnessite, Na4Mn14O27·9H2O), which were detected in soils by XRD and SEM/EDS. In contrast, Cd was the most mobile contaminant and was predominantly present in the exchangeable fraction. Arsenic was bound to the residual and reducible fractions (corresponding to Fe oxides or to unidentified Fe-Pb arsenates). SEM/EDS observations indicate the predominant affnity of Pb for Mn oxides, and to a lesser extent, for Fe oxides. Thus, a more suitable SEA procedure should be used for these mining-affected soils to distinguish between the contaminant fraction bound to Mn oxides and Fe oxides.A. VANEK V. ETTLER T. GRYGAR L. BORUVKA O. EBEK O. DRBEK 2008Pedosphere2008,18,4:8
10阿司匹林或利伐沙班对髋膝关节置换术后VTE的预防效果显示文摘静脉血栓栓塞(venous thromboembolism,VTE)是全髋关节置换(total hip arthroplasty,THA)或全膝关节置换(total knee arthroplasty,TKA)常见的术后并发症。诸多临床试验研究和Meta分析结果表明,阿司匹林在预防THA或TKA术后VTE(近端深静脉血栓形成或肺栓塞)方面可能是有效的,但缺乏与直接口服抗凝剂在出院后预防效果方面的比较。Anderson DR Dunbar M Murnaghan J 李炳林 章莹 2018中国骨科临床与基础研究杂志2018,10,2:8
11气体吸附法进行孔径分析进展--密度函数理论(DFT)及蒙特卡洛法(MC)的应用显示文摘 气体吸附法是获得多孔材料全面表征的极好方法,它可以反映比表面、孔分布和孔隙度等方面的信息,但是,这需要对吸附过程有一个详细的了解,包括在多孔材料上流体的吸附和相变化及其对吸附等温线的影响,这是表面分析和孔分析的基础.孔宽、孔形及有效的吸附能是测定孔填充过程的因子.如果是所谓微孔(按照IUPAC分类,孔宽<2 nm)孔填充是一个连续的过程;而如果是介孔(中孔,孔宽在2~50 nm之间),孔填充则是气体在孔内的凝聚过程,它表现为一级气-液相转移.……杨正红 Dr Mattias Thommes 2005中国粉体技术2005,11,z1:8
12Piezoelectric and piezomagnetic materials and their function in transducer显示文摘Berlincourt DA Curran DR Jaffe H 1964Physical Acoustics1964,,:7
13Δ4-3-oxosteroid-5β-reductase deficiency: Responses to oral bile acid therapy and long-term outcomes显示文摘BACKGROUND Disorders of primary bile acid synthesis may be life-threatening if undiagnosed,or not treated with primary bile acid replacement therapy. To date, there are few reports on the management and follow-up of patients with Δ4-3-oxosteroid 5β-reductase(AKR1 D1) deficiency. We hypothesized that a retrospective analysis of the responses to oral bile acid replacement therapy with chenodeoxycholic acid(CDCA) in patients with this bile acid synthesis disorder will increase our understanding of the disease progression and permit evaluation of this treatment regimen as an alternative to the Food and Drug Administration(FDA) approved drug cholic acid, which is currently unavailable in China.AIM To evaluate the therapeutic responses of patients with AKR1 D1 deficiency to oral bile acid therapy, specifically CDCA.METHODS Twelve patients with AKR1 D1 deficiency, confirmed by fast atom bombardment ionization-mass spectrometry analysis of urine and by gene sequencing for mutations in AKR1 D1, were treated with differing doses of CDCA or ursodeoxycholic acid(UDCA). The clinical and biochemical responses to therapy were monitored over a period ranging 0.5-6.4 years. Dose adjustment, to optimize the therapeutic dose, was based on changes in serum biochemistry parameters,notably liver function tests, and suppression of the urinary levels of atypical hepatotoxic 3-oxo-Δ4-bile acids measured by mass spectrometry.RESULTS Physical examination, serum biochemistry parameters, and sonographic findings improved in all 12 patients during bile acid therapy, except one who underwent liver transplantation. Urine bile acid analysis confirmed a significant reduction in atypical hepatotoxic 3-oxo-Δ4 bile acids concomitant with clinical and biochemical improvements in those patients treated with CDCA. UDCA was ineffective in down-regulating endogenous bile acid synthesis as evidenced from the inability to suppress the urinary excretion of atypical 3-oxo-Δ4-bile acids. The dose of CDCA required for optimal clinical and biochemical responses varied from 5.5-10 mg/kg per day among patients based on maximum suppression of the atypical bile acids and improvement in serum biochemistry parameters, and careful titration of the dose was necessary to avoid side effects from CDCA.CONCLUSION The primary bile acid CDCA is effective in treating AKR1 D1 deficiency but the therapeutic dose requires individualized optimization. UDCA is not recommended for long-term management.Mei-Hong Zhang Kenneth DR Setchell Jing Zhao Jing-Yu Gong Yi Lu Jian-She Wang 2019World Journal of Gastroenterology2019,25,7:7
14Antibody detection and sequence analysis of sporadic HEV in Xiamen region显示文摘Huang RT Li XY Xia XB Yuan XT Liu MX Li DR 1999World Journal of Gastroenterology1999,5,3:6
15美国仔猪早期断奶技术显示文摘1早期断奶的概念早期断奶是指区别于传统的28~35早日龄或更大日龄断奶,一般称在21日龄以内断奶为早期断奶。如表一所示,早期断奶能有效提高母猪年产窝数及产仔数、提高产房设备利用率、降低设备成本。表1不同日龄断奶对产胎数、产仔数、产床利用的影响断奶日龄...Dr Fang Chi 计乔平 王津豫 1998当代畜牧1998,,2:6
16D-二聚体预测稳定型冠状动脉性心脏病患者的长期病因特异性死亡率、心血管事件和癌症显示文摘交联纤维蛋白的降解产物D-二聚体是高凝状态和血栓形成事件的标志。D-二聚体水平中度升高与血管疾病患者静脉和动脉事件的风险相关。在缺血性疾病长期普伐他汀干预(long-term intervention with pravastatin in ischemic disease,LIPID)试验中,研究者在存在其他危险因素的背景下,评估了D-二聚体水平在预测长期血管转归、病因特异性死亡率和新发癌症中的作用。刘青 叶鹏 Simes J Robledo KP White HD Espinoza D Stewart RA Sullivan DR Zeller T Hague W Nestel PJ Glasziou PP Keech AC Elliott J Blankenberg S Tonkin AM LIPID study investigators 2018中华高血压杂志2018,26,3:6
17Self-Healing Concrete with Crystalline Admixture——A Review显示文摘The scope of the present paper is to understand the effects of crystalline admixture on the selfhealing capacity of the cementitious composites. Previous studies were examined and a conclusion was drawn to the effect that different additives to crystalline admixture tend to improve self-healing of concrete for larger cracks. It is recommended that initial treatment with chemical admixture can stimulate and heal further cracks and it has the better repeatability trend in mixing with the concretes and mechanical recovery is possible even under repetitive preloading. Effective self-healing with chemical admixtures even under open-air exposure, leads to study the importance of a service ability design parameter including the maximum allowable crack width by repeatability analysis as a function of the exposure with the concept of sealable crack width.A Ravitheja Dr T Chandra Sekhara Reddy Dr C Sashidhar 2019Journal of Wuhan University of Technology(Materials Science)2019,34,5:6
18Ozone Profile Retrieval from Satellite Observation Using High Spectral Resolution Infrared Sounding Instrument显示文摘This paper presents a preliminary result on the retrieval of atmospheric ozone profiles using an im- proved regression technique and utilizing the data from the Atmospheric InfraRed Sounder (AIRS), a hyper-spectral Instrument expected to be flown on the EOS-AQUA platform in 20D2. Simulated AIRS spectra were used to study the sensitivity of AIRS radiance on the tropospheric and stratospheric ozone changes, and to study the impact of various channel combinations on the ozone profile retrieval. Sensitivity study results indicate that the AIRS high resolution spectral channels between the wavenumber 650- 800 cm-1 provide very useful information to accurately retrieve tropospheric and stratospheric ozone pro- files Eigenvector decomposition of AIRS spectra indicate that no more than 100 eigenvectors are needed to retrieve very accurate ozone profiles. The accuracy of the retrieved atmospheric ozone profile from the pres- ent technique and utilizing the AIRS data was compared with the accuracy obtained from current Advanced TIROS Operational Vertical Sounder (ATOVS) data aboard National Oceanic and Atmospheric Admini- stration (NOAA) satellites As expected, a comparison of retrieval results confirms that the ozone profile re- trieved with the AIRS data is superior to that ofYanni Qu, Mitchell D. Goldberg and Murty Divakarla Research and Data System Corporation, 7833 Walker Dr Greenbelt. MD 20770 National Eivironment Satellite Data and Information Service, Office of Research and Application, World Weather Building. 5200 Auth 2001Advances in Atmospheric Sciences2001,18,5:5
19语音压缩技术及其应用的进展显示文摘文中介绍了语音压缩技术的基本原理和算法,并着重分析了当前流行的几种语音压缩算法的优缺点,同时介绍了相应的一些语音压缩产品,最后对这门技术发展前景作了展望。郑洪英 郭东辉 纪安妮 刘瑞堂 Dr Gerard Parr 2000计算机与网络2000,,5:5
20Endoscopic transnasal craniotomy and the resection of craniopharyngioma显示文摘OBJECTIVES/HYPOTHESIS: To describe the utility of a large transnasal craniotomy and its reconstruction in the surgicalmanagement of patients with craniopharyngioma. STUDY DESIGN: Observational retrospective cohort study. METHODS:Retrospective review of patients treated in an academic neurosurgery/rhinology practice between 2000 and 2007.Stamm AC Vellutini E Harvey RJ Nogeira JF Herman DR 2008中国神经肿瘤杂志2008,6,3:5
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