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| 1 | 经活检证实心肌炎患者的存活情况:一项关于组织病理学、临床和血流动力学预测因素的长期回顾性分析显示文摘Objective: We hypothesized that histopathology predicts survival without cardiac transplantation in patients with biopsy- proven myocarditis. Background: The role of endomyocardial biopsy in diagnosing myocarditis remains controversial. Histopathology has been integrated with clinical and hemodynamic features to predict prognosis. However, the influence of histopathology on survival >5 years has not been explored. Methods: We retrospectively identified 112 consecutive patients with histopathologic confirmation of myocarditis. We examined these patients’ clinical presentation, hemodynamic assessment, hospital course, and treatment. We selected 14 variables that might influence survival without cardiac transplantation. Results: A total of 62(55% ) of 112 patients had lymphocytic myocarditis; 88(79% ) and 63(56% ) were alive without cardiac transplantation at 1 and 5 years, respectively. Median follow- up was a mean 95.5 months and median 74.5 months. Among the 55 with complete data of the 14 candidate predictor variables, age, sex, and clinical presentation with congestive heart failure and ventricular(ventricular tachycardia or fibrillation) or atrial arrhythmias(atrial fibrillation or flutter) did not predict the study end point of death or need for transplantation. In univariate analysis, pulmonary capillary wedge pressure ≥ 15 mm Hg significantly predicted the study end point. In multivariate analysis, pulmonary capillary wedge pressure ≥ 15 mm Hg and histopathology of lymphocytic, granulomatous, or giant cell myocarditis each significantly predicted mortality or transplant(P=.047, P=.013, and P=.054, respectively) on cumulative survival without cardiac transplantation. Conclusions: Histopathology predicts long- term survival in patients with myocarditis. Clinical presentation, including presentation with congestive heart failure, ventricular tachycardia/ ventricular fibrillation, or atrial fibrillation/atrial flutter, does not predict survival without transplantation. Endomyocardial biopsy can play a role in predicting transplant- free survival in patients with myocarditis. | Magnani J.W. Suk Danik H.J. Dec Jr. G.W. DiSalvo T.G. 高登峰 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，6： | 2 |
| 2 | Thermoelectric cooling and power generation 显示文摘 | Francis J DiSalvo | 1999 | Science1999，30，285： | 2 |
| 3 | Infection Caused by Penieillium Marneffei显示文摘 | Disalvo AF Fickling AM Ajello L | 1973 | AM J Clin Pathol1973，60，2： | 1 |
| 4 | Adenosine mediated relaxation and activation of cyclic AMP dependent protein kinase in coronary arterial smooth muscle显示文摘 | Walus K Disalvo J | 1984 | J Pharmacol Exp Ther1984，228，： | 1 |
| 5 | Vibrio anguillarum and larval mortality in a California coastal shellfish hatchery显示文摘 | DISALVO L H BLECKA J ZEBAL R | 1978 | ApplEnvironMicrobiol1978，35，： | 1 |
| 6 | Surface properties of bifidobacterial strains of human origin 显示文摘 | Pe'rez PF Minnaard Y Disalvo EA | 1998 | Applied and Environmental Microbiology1998，64，： | 1 |
| 7 | Infection case Penicillium marnrffei:description of first natural infection in man显示文摘 | Disalvo AF Fickling AM | 1973 | Am J Clin Pathol1973，60，： | 1 |
| 8 | Thermoelectric Cooling and Power Genera- tion 显示文摘 | Disalvo F J | 1999 | Science1999，285，： | 1 |
| 9 | Thermoelectric cooling and power generation 显示文摘 | Disalvo F J | 1999 | Science1999，285，： | 1 |
| 10 | Purification and characterization of a naturally occurring vascular endothelial growth factor placenta growth factor heterodimer显示文摘 | Disalvo J Bayne M L Conn G | 1995 | J Biol Chem1995，270，13： | 1 |
| 11 | Thermoelectric cooling and power generation显示文摘 | DISALVO F J | 1999 | Science1999，285，： | 1 |
| 12 | Thermoelectric cooling and power generation 显示文摘 | Disalvo F J | 1999 | Science1999，285，： | 1 |
| 13 | Regulation of NIH3T3 cell G1 phase transit by ,serum during exponential growth显示文摘 | Disalvo C V Zhang D jacobberger J W | 1995 | Cells Prolif1995，28，6： | 1 |
| 14 | Dramatic impurity effects on the charge-density wave in potassium molybdenum bronze显示文摘 | SCHNEEMEYER L F DISALVO F J SPENGLER S E | 1984 | Phys Rev B1984，30，8： | 1 |
| 15 | Thermoelectric cooling and power generation 显示文摘 | DiSalvo FJ | 1999 | Science1999，285，： | 1 |
| 16 | Thermoelectric Cooling and Power Generating显示文摘 | DiSalvo F J | 1999 | Science1999，285，： | 1 |
| 17 | Thermoelectric cooling and power generation显示文摘 | DiSalvo F J | 1999 | Science1999，285，： | 1 |
| 18 | Lithium incorporation by V6O13 and related vanadium (+4, +5) oxide cathode materials显示文摘 | MURPHY D W CHRISTIAN P A DISALVO F J CARIDES J N WASZCZAK J V | 1981 | J Electrochemical Society1981，128，10： | 1 |
| 19 | Thermoelectric cooling and power generation显示文摘 | DISALVO F J | 1999 | Science1999，285，5428： | 1 |
| 20 | Intermetallics as novel supports for Pt monolayer 02 reduction electrocatalysts: potential for significantly improving properties 显示文摘 | GHOSH T VUKMIROVIC M B DISALVO F J | 2009 | Journal of the American Chemical Society2009，132，3： | 1 |
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