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| 1 | 非ST段抬高型急性冠状动脉综合征患者中的肥胖矛盾现象:来自CRUSADE(对不稳定型心绞痛患者进行快速风险分层能否减少早期实施ACC/AHA指南的不良预后)质量改进研究的结果显示文摘Background: Although obesity is a known risk factor for coronary artery disease, its impact on the presentation, treatment, and outcome of patients with acute coronary syndromes(ACS) has not been well studied. Methods: Using data from the CRUSADE Initiative, we compared inhospital treatments and clinical outcomes of 80 845 patients with high-risk non-ST-segment elevation(NSTE) ACS(positive cardiac markers and/or ischemic ST-segment changes) to determine whether there was an association with body mass index(BMI[kg/m2]). Patient weights were categorized according to World Health Organization classifications: Underweight(BMI< 18.5), Normal range(BMI 18.5-24.9), Overweight(BMI 25-29.9), Obese Class I(BMI 30-34.9), Obese Class Ⅱ(BMI 35-39.9), and Extremely Obese(BMI≥40). Results: Most(70.5%) of the CRUSADE patients were classified as overweight or obese; these patients were younger and more likely to present with comorbid conditions, including diabetes mellitus, hypertension, and hyperlipidemia. Medications given during the first 24 hours and invasive cardiac procedures recommended by the American College of Cardiology/American Heart Association guidelines for NSTE ACS were more commonly used in these patients. The incidence of death and death and reinfarction, adjusted for covariates, were generally lower in overweight and obese patients, compared with normal-weight patients, but higher in underweight and extremely obese patients. Conclusions: Most patients with NSTE ACS are overweight or obese. These patients receive more aggressive treatment, and, except for the extremely obese, have less adverse outcomes compared with underweight and normal-weight patients. Although obesity appears to be a risk factor for developing ACS at a younger age, it also appears to be associated with more aggressive ACS management and, ultimately, improved outcomes. | Diercks D.B. Roe M.T. Mulgund J. 罗亮 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，，12： | 2 |
| 2 | Optimizing treatment and outcomes in acute heart failure:beyond initial triage显示文摘 | SILVER M A PEACOCK W F 4th DIERCKS D B | 2006 | Congest Heart Fail2006，12，： | 1 |
| 3 | Gender differences in time to presentation for myocardial infarction before and after a national women's cardiovascular awareness campaign: a temporal analysis from the Can Rapid Risk Stratification of Unstable Angina Patients Suppress ADverse Outcomes with Early Implementation ( CRUSADE ) and the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network-Get with the Guidelines (NCDR ACTION Registry-GWTG)显示文摘 | Diercks DB Owen KP Kontos MC | 2010 | Am Heart J2010，160，1： | 1 |
| 4 | IL - 10 promotes secre-tion of S100A8/A9 from human monocytes trough an inclusionin plasma membranes 显示文摘 | Diercks BP Hauschildt I Stab F | 2013 | Scand J Immunol2013，77，2： | 1 |
| 5 | The importance of microbial as a cardiovascular risk indicator 显示文摘 | Diercks GF Van Boven AJ Hillege JL | 2002 | Can J Cardiol2002，18，5： | 1 |
| 6 | The JNK inhibitor XG- 102 protects against TNBS-induced colitis显示文摘 | Reinecke K Eminel S Dierck F | 2012 | PLoS One2012，7，30： | 1 |
| 7 | Gentle thawing of the frozen shoulder:a prospective study of supervised neglect versus intensive physicaltherapy in seventy seven patients with frozen shoulder syndromefollowed up for two years显示文摘 | Diercks RL Stevens M | 2004 | J Shoulder Elbow Surg2004，13，5： | 1 |
| 8 | Theimportance of microalbuminuria as a cardiovascular risk indicator 显示文摘 | Diercks GF Van Boven A J Hillege J L | 2002 | Can J Cardiol2002，18，5： | 1 |
| 9 | Journal of Nuclear Material显示文摘 | Smith D L Loomis B A Diercks D R | 1985 | 135:1251985，135，： | 1 |
| 10 | Identifying and Managing Troubled Bor- rowers in Asset- based- lending Scenarios 显示文摘 | Diercks L A | 2004 | Commercial Lending Review2004，19，3： | 1 |
| 11 | Superconductor Film growth on LaGaO3 Substrates by Liquid Phase epitaxy 显示文摘 | Belt R F Ings J Diercks G | 1990 | Applied Physics Letters1990，56，： | 1 |
| 12 | Utilization and impact of pre hospital electrocardiograms for patients with acute ST-segment elevation myocardial infarction: data from the NCDR (National Cardiovascular Data Registry) ACTION (A- cute Coronary Treatment and Intervention Outcomes Network) registry显示文摘 | Diercks DB Kontos MC Chen AY | 2009 | J Am Coil Cardiol2009，53，： | 1 |
| 13 | Urinary Albu rain Excretion Predicts Cardiovascular and Noneardiovaseular Mortality in General Population 显示文摘 | Hillege HL Fidler V Diercks GF | 2002 | Circulation2002，106，14： | 1 |
| 14 | Urinary albumin excre- tion predicts cardiovascular and noncardiovascular mortality in general population 显示文摘 | Hillege HL Fidler V Diercks GF | 2002 | Circulation2002，106，14： | 1 |
| 15 | Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population显示文摘 | Hillege HL Fidler V Diercks GFs | 2002 | Circulation2002，106，14： | 1 |
| 16 | Evaluation of chest pain suspicious for acute coronary syndrome: use of an accelerated diagnostic protocol in a chest pain evaluation unit显示文摘 | Kirk JD Diercks DB Turnipseed SD | 2000 | Am J Cardiol2000，85，： | 1 |
| 17 | Overview of steam generator tube degradation and integrity issues 显示文摘 | Diercks D R Shack W J Muscar J | 1999 | Nucl Engin Design1999，194，： | 1 |
| 18 | Cost-effectiveness ofLower Extremity Compression Ultrasound in Emergency Depart-ment Patients With a High Risk of Hemodynamically Stable Pul-monary Embolism显示文摘 | Ward MJ Sodickson A Diercks DB | 2011 | Academic Emergency Medicine2011，18，1： | 1 |
| 19 | Morphine and out- comes in acute decompensated heart failure : an ADHERE analysis 显示文摘 | Peacock WF Hollander JE Diercks DB | 2008 | Emerg Med J2008，25，4： | 1 |
| 20 | Generating the Bezier points of β-spline curve显示文摘 | Dierck P Tytgat B | 1989 | Computer Aided Geometric Design1989，6，2： | 1 |
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