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| 1 | Diffusion magnetic resonance imaging: A molecular imaging tool caught between hope, hype and the real world of “personalized oncology”显示文摘'Personalized oncology' is a multi-disciplinary science, which requires inputs from various streams for optimal patient management. Humongous progress in the treatment modalities available and the increasing need to provide functional information in addition to the morphological data; has led to leaping progress in the field of imaging. Magnetic resonance imaging has undergone tremendous progress with various newer MR techniques providing vital functional information and is becoming the cornerstone of 'radiomics/radiogenomics'. Diffusionweighted imaging is one such technique which capitalizes on the tendency of water protons to diffuse randomly in a given system. This technique has revolutionized oncological imaging, by giving vital qualitative and quantitative information regarding tumor biology which helps in detection, characterization and post treatment surveillance of the lesions and challenging the notion that 'one size fits all'. It has been applied at various sites with different clinical experience. We hereby present a brief review of this novel functional imaging tool, with its application in 'personalized oncology'. | Abhishek Mahajan Sneha S Deshpande Meenakshi H Thakur | 2017 | World Journal of Radiology2017，9，6： | 3 |
| 2 | Current scenario of traditional medicines in management of diabetic foot ulcers:A review显示文摘Diabetic foot infections and diabetic foot ulcers(DFU)cause significant suffering and are often recurring.DFU have three important pathogenic factors,namely,microangiopathy causing local tissue anoxia,neuropathy making the foot prone to injuries from trivial trauma,and local tissue hyperglycaemia favouring infection and delaying the wound healing.DFU have been the leading cause for non-traumatic amputations of part or whole of the limb.Western medicines focus mainly on euglycaemia,antimicrobials,debridement and wound cover with grafts,and off-loading techniques.Advances in euglycaemic control,foot care and footwear,systemic antimicrobial therapy,and overall health care access and delivery,have resulted in an overall decrease in amputations.However,the process of wound care after adequate debridement remains a major cost burden globally,especially in developing nations.This process revolves around two basic concerns regarding control/eradication of local infection and promotion of faster healing in a chronic DFU without recurrence.Wound modulation with various dressings and techniques are often a costly affair.Some aspects of the topical therapy with modern/Western medicines are frequently not addressed.Cost of and compliance to these therapies are important as both the wounds and their treatment are“chronic.”Naturally occurring agents/medications from traditional medicine systems have been used frequently in different cultures and nations,though without adequate clinical base/relevance.Traditional Chinese medicine involves restoring yin-yang balance,regulating the‘chi’,and promoting local blood circulation.Traditional medicines from India have been emphasizing on‘naturally’available products to control wound infection and promote all the aspects of wound healing.There is one more group of chemicals which are not pharmaceutical agents but can create acidic milieu in the wound to satisfy the above-mentioned basic concerns.Various natural and plant derived products(e.g.,honey,aloe vera,oils,and calendula)and maggots are also used for wound healing purposes.We believe that patients with a chronic wound are so tired physically,emotionally,and financially that they usually accept native traditional medicine which has the same cultural base,belief,and faith.Many of these products have never been tested in accordance to“evidence-based medicine.”There are usually case reports and experience-based reports about these products.Recently,there have been some trials(in vitro and in vivo)to verify the claims of usage of traditional medicines in management of DFU.Such studies show that these natural products enhance the healing process by controlling infection,stimulating granulation tissue,antimicrobial action,promoting fibroblastic activity and collagen deposition,etc.In this review,we attempt to study and analyse the available literature on results of topical traditional medicines,which are usually advocated in the management of DFU.An integrated and‘holistic’approach of both modern and traditional medicine may be more acceptable to the patient,cost effective,and easy to administer and monitor.This may also nevertheless lead to further improvement in quality of life and decrease in the rates of amputations for DFU. | Abhijit S Rayate Basavraj S Nagoba Sachin S Mumbre Hardi B Mavani Ajay M Gavkare Advait S Deshpande | 2023 | World Journal of Diabetes2023，14，1： | 3 |
| 3 | Molecular and industrial aspects of glucose isomerase 显示文摘 | Bhosale S H Rao M B Deshpande V V | 1996 | Microbiol Reveiw1996，60，： | 1 |
| 4 | Finite element analysis of the dynamic response of clamped sandwich beams subjected to loading显示文摘 | Qiu X Deshpande V S Fleck N A | 2003 | European Journal of Mechanics A: Solids2003，22，： | 1 |
| 5 | Aspects of positive ageing 显示文摘 | Kochar S C Singh H | 1986 | Journal of Applied Probability1986，23，： | 1 |
| 6 | Ethical Climate and Managerial Success in Russian Organizations 显示文摘 | Deshpande S P George E Joseph J | 2000 | Journal of Business Ethics2000，23，2： | 1 |
| 7 | Experimental and numerical characterization of the cyclic thermomechanical behavior of a high temperature forming tool alloy显示文摘 | LEEN S B DESHPANDE A HYDE T H | 2010 | Journal of Manufacturing Science and Engineering-Transaction of the ASME2010，132，05： | 1 |
| 8 | Direct conversion of cellulose/hemicellulose to ethanol by Neurospom crassa显示文摘 | Deshpande V Keskar S Mishra C & Rao M | 1985 | Enzyme Microb Technol1985，7，： | 1 |
| 9 | Effects of Pores and Interfaces on Effective Properties of Plasma Sprayed Zirconia Coatings显示文摘 | Wang Z Kulkarni A Deshpande S | 2003 | Acta Mater2003，51，： | 1 |
| 10 | Microwave - hydrothermal synthesis of equi - axed and submicron -sized BaTiO3 powders 显示文摘 | KHOLLAM Y B DESHPANDE A S | 2001 | Mater Chem Phys2001，71，： | 1 |
| 11 | Polymerization of styrene with VOC13-aluminum alkyls显示文摘 | Anand L C Deshpande A B Kapur S L | 1967 | J Poiym Sci Part A-11967，，5： | 1 |
| 12 | UHF wind profiler observations of monsoon low level jet over Pune显示文摘 | JOSHI R R NARENDRA S DESHPANDE S M | 2006 | Indian Journal of Radio & Space physics2006，35，： | 1 |
| 13 | CREB3L2- PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis 显示文摘 | Lui WO Zeng L Rehrmann V Deshpande S | 2008 | Cancer Res2008，68，17： | 1 |
| 14 | Synthesis of vanillin and 4-hydroxy benzaldehyde by a reaction scheme involving condensation of phenols with glyoxylic acid显示文摘 | Kalikar Rajendra G Deshpande Ramesh S | 1986 | Chemical Technology and Biotechnology1986，36，1： | 1 |
| 15 | Effect of Cu substitution on the magnetic and electrical properties of Ni-Zn Ferrite synthesized by soft chemical method 显示文摘 | Shrotri J J Kulkami S D Deshpande C E | 1999 | Mater Chem Phys1999，59，： | 1 |
| 16 | Size effects in uniaxial deformation of single and polycrystals: a discrete dislocation plasticity analysis显示文摘 | Balint D S Deshpande V S Needleman A | 2006 | Modeling and simulation in materials science and engineering2006，14，： | 1 |
| 17 | Catalytic Vapor Phase Reduction of Nitrobenzene to Aniline in Fluidized Beds显示文摘 | Deshpande P K Kuloor N R | 1963 | Chemical Age of India1963，14，： | 1 |
| 18 | The incidence of infectious complications of central venous catheters at the subclavian,internal jugular,and femoral sites in an intensive care unit population显示文摘 | Deshpande K S Hatem C Ulrich H L | 2005 | Crit Care Med2005，33，1： | 1 |
| 19 | Reversible lithium-ion insertion in molybdenum oxide nanoparticles显示文摘 | Lee S H Kim Y H Deshpande R | 2008 | Adv Mater2008，20，： | 1 |
| 20 | Invasive pulmonary aspergillosis : A study of 39 cases at autopsy 显示文摘 | Vaideeswar P Prasad S Deshpande JR | 2004 | J Postgrad Med2004，50，： | 1 |
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