|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 经活检证实心肌炎患者的存活情况:一项关于组织病理学、临床和血流动力学预测因素的长期回顾性分析显示文摘Objective: We hypothesized that histopathology predicts survival without cardiac transplantation in patients with biopsy- proven myocarditis. Background: The role of endomyocardial biopsy in diagnosing myocarditis remains controversial. Histopathology has been integrated with clinical and hemodynamic features to predict prognosis. However, the influence of histopathology on survival >5 years has not been explored. Methods: We retrospectively identified 112 consecutive patients with histopathologic confirmation of myocarditis. We examined these patients’ clinical presentation, hemodynamic assessment, hospital course, and treatment. We selected 14 variables that might influence survival without cardiac transplantation. Results: A total of 62(55% ) of 112 patients had lymphocytic myocarditis; 88(79% ) and 63(56% ) were alive without cardiac transplantation at 1 and 5 years, respectively. Median follow- up was a mean 95.5 months and median 74.5 months. Among the 55 with complete data of the 14 candidate predictor variables, age, sex, and clinical presentation with congestive heart failure and ventricular(ventricular tachycardia or fibrillation) or atrial arrhythmias(atrial fibrillation or flutter) did not predict the study end point of death or need for transplantation. In univariate analysis, pulmonary capillary wedge pressure ≥ 15 mm Hg significantly predicted the study end point. In multivariate analysis, pulmonary capillary wedge pressure ≥ 15 mm Hg and histopathology of lymphocytic, granulomatous, or giant cell myocarditis each significantly predicted mortality or transplant(P=.047, P=.013, and P=.054, respectively) on cumulative survival without cardiac transplantation. Conclusions: Histopathology predicts long- term survival in patients with myocarditis. Clinical presentation, including presentation with congestive heart failure, ventricular tachycardia/ ventricular fibrillation, or atrial fibrillation/atrial flutter, does not predict survival without transplantation. Endomyocardial biopsy can play a role in predicting transplant- free survival in patients with myocarditis. | Magnani J.W. Suk Danik H.J. Dec Jr. G.W. DiSalvo T.G. 高登峰 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，6： | 2 |
| 2 | Influence of genetic variation in the C-reactive protein gene on the inflammatory response during and after acute coronary ischemia显示文摘 | Suk Danik J Chasman DI Cannon CP | 2006 | Ann Hum Genet2006，70，6： | 1 |
| 3 | Modulation of cardiac gap junction expression and arrhythmic susceptibility显示文摘 | Danik SB Liu F Zhang J | 2004 | Circ Res2004，95，10： | 1 |
| 4 | Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABA ergic inhibition in hippocampal CA1 pyramidal neurons显示文摘 | Hellstrom IC Danik M Luheshi GN | 2005 | Hippocampus2005，15，5： | 1 |
| 5 | Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts显示文摘 | Danik SB Rosner G Lader J | 2008 | FASEB J2008，22，： | 1 |
| 6 | CMR quantifi- cation of myocardial scar provides additive prognostic informa- tion in nonischemic cardiomyopathy 显示文摘 | Neilan TG Coelho-Filho OR Danik SB | 2013 | JACC Cardiovascular imaging2013，6，： | 1 |
| 7 | Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons显示文摘 | Hellstrom IC Danik M Luheshi GN | 2005 | Hippocampus2005，15，： | 1 |
| 8 | Modulation of cardiac gap junctionexpression and arrhythmic susceptibility 显示文摘 | Danik SB Liu F Zhang J | 2004 | Circ Res2004，95，10： | 1 |
| 9 | Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-b-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons显示文摘 | Hellstrom IC Danik M Luheshi GN | 2005 | Hippocampus2005，15，5： | 1 |
| 10 | Focal gap junction uncoupling and spontaneous ventricular ectopy显示文摘 | Gutstein DE Danik SB Lewitton S | 2005 | Am J Physiol Heart Circ Physiol2005，289，： | 1 |
| 11 | Protitypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation显示文摘 | Bastianetto S Danik M Mennicken F | 2006 | BMCNeurosci2006，7，28： | 1 |
| 12 | Lipoprotein(a),Hormone Replacement Therapy,and Risk of Future Cardiovascular Events显示文摘 | Suk Danik J Rifai N Buring JE | 2008 | J Am Coll Cardiol2008，52，： | 1 |
| 13 | Novel loci,including those related to Crohn disease,psoriasis,and inflammation,identified in a genome-wide association study of fibrinogen in 17 686 women:the Women′s Genome Health Study显示文摘 | Danik J S Paré G Chasman D I | 2009 | Circ Cardiovasc Genet2009，2，2： | 1 |
| 14 | Modulation of cardiac gap junction expression and arrhythmic susceptibility显示文摘 | Danik SB Liu F Zhang J | 2004 | Circ Res2004，95，： | 1 |
| 15 | Influence of genetic variation in the C-reactive protein gene on the in- flammatory response during and after acute coronary is- chemia显示文摘 | Danik JS Chasman DI Cannon CP | 2006 | Ann Hum Genet2006，70，6： | 1 |
| 16 | Influence of genetic variation in the C - reactive p rotein gene on the in flammatory response during and af- ter acute coronary is ehemia显示文摘 | Danik JS Chasman D I | 2006 | Ann Hum Genet2006，70，6： | 1 |
| 17 | Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABAergic inhibition in hippocampal CA 1 pyramidal neurons显示文摘 | Hellstrom IC Danik M Luheshi GN | 2005 | Hippocampus2005，15，： | 1 |
| 18 | Localization of sulfated glycoprotein-2/clusterin mRNA in the rat brain by in situ hybridization显示文摘 | Danik M Chabot JG Hassan-Gonzalez D | 1993 | J Comp Neurol1993，334，2： | 1 |
| 19 | Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons显示文摘 | Hellstrom IC Danik M Luheshi GN | 2005 | Hippocampus2005，15，5： | 1 |
| 20 | Effects of temperature on fatigue and fracture 显示文摘 | Young D G Danik J A | 1994 | Rubber Chemistry and Technology1994，67，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员