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| 1 | ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer显示文摘 | Shunrong Ji Yi Qin Si Shi Xiangyuan Liu Hongli HU Hu Zhou Jing Gao Bo Zhang Wenyan Xu Jiang Liu Dingkong Liang Liang Liu Chen Liu Jiang Long Haijun Zhou Paul J Chiao Jin Xu Quanxing Ni Daming Gao Xianjun Yu | 2015 | Cell Research2015，25，5： | 19 |
| 2 | Effects of longitudinal range-gorge terrain on the eco-geographical pattern in Southwest China显示文摘在纵的高耸山和深山谷之间的平行安排在本地自然环境的区别上有重要效果的瓷器西南的特殊地面模式和在这个区域的 eco 地理的模式。 1:50,000 纵的范围峡区域( LRGR )的数字举起模型( DEM )数据,从车站建立的气象学的观察数据到 2010 ,水文学观察数据,规范的差别植被索引( NDVI )和网象 1:1,000,000 植被类型数据一样的 MOD13 和 MOD17 的主要生产率( NPP )产品被使用。包括大气的蒸汽内容,降水,干旱 / 湿度索引,表面流量,和温度索引包括的表面的潮湿索引平均温度,年度积累的温度,全部的太阳的放射被选择。在这个区域基于 ANUSPLIN 花键功能, GIS 空间分析,小浪分析和风景模式分析,地区性的区别特征和热水的模式,生态系统结构和功能的主要控制的因素被分析在 eco 地理的元素的地区性的区别上揭示地面模式的效果。结果显示出那:在 LRGR 由地面模式,潮湿,温度和热影响了作为断断续续的纬差别和连续经纱扩展显示出重要分发特征。纵的山和山谷不仅在主要表面材料和精力的转移上有纵贯的走廊功能和散开效果,而且有东方西方障碍功能和堵住的效果。特殊地志的模式在植被风景差异和生态系统结构和功能的空间模式上有重要影响,它是植被风景差异和生态系统的空间分发上的主要控制的因素。小浪变化分析反映环境因素, NDVI 和 NPP 的空间 anisotropy,当小浪一致性分析象与控制度的量的关系一样在 NDVI 和 NPP 的空间分发上揭示控制因素时。在 LRGR 的特殊地面模式是在这个区域的 eco 地理的地区性的区别上的主要影响因素。当在 LRGR 的 eco 地理的地区性的系统的主要典型、特殊空间特征被形成,在 zonality 和 non-zonality 的联合效果下面,有走廊障碍的法律工作。 | PAN Tao WU Shaohong HE Daming DAI Erfu LIU Yujie | 2012 | Journal of Geographical Sciences2012，22，5： | 13 |
| 3 | The variation and regional differences of precipitation in the Longitudinal Range-Gorge the Region显示文摘这份报纸基于记录在 36 个气象学的车站在 1960 ~ 2001 期间观察了的每日的降雨在纵的范围峡区域(LRGR ) 检验降水的地区性的差别。在不同空间、时间的规模的降水的地区性的差别被分析,在完成在 LRGR 的特殊走廊障碍功能下面。结果显示很靠近的连接在地区性的差别和走廊障碍功能之间存在:在北 LRGR 的大多数区域(> 26 湩? | HE DaMing LI ShaoJuan ZHANG YiPing | 2007 | Chinese Science Bulletin2007，52，A02： | 13 |
| 4 | Transboundary hydrological effects of hydropower dam construction on the Lancang River显示文摘 | HE Daming FENG Yan GAN Shu Darrin Magee YOU Weihong | 2006 | Chinese Science Bulletin2006，51，B11： | 13 |
| 5 | Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders显示文摘孤独性光谱混乱(ASD ) 是有异构的病原学的许多人的神经病学的混乱。E3 ubiquitin (Ub ) 的活动过度 ligase UBE3A,不完全地源自 15q11-q13 拷贝数字变化,为世界范围的 ASD 盒子的 1%-3% 的报道,而是内在的机制遗体描绘了。这里,我们报导 ALDH1A2 的功能, retinoic 酸(RA ) 的限制率的酶合成,被 UBE3A 否定地以一种 ubiquitylation 依赖的方式调整。过多的 UBE3A 剂量被发现损害调停 RA 的 neuronal homeostatic synaptic 粘性。象 ASD 一样症状被 overexpressing UBE3A 在前额的外皮或由一个 ALDH1A 对手的管理在老鼠概括,而 RA 补充显著地减轻了过多的 UBE3A 导致剂量的象 ASD 一样显型。由识别在 ASD 作为内在的机制发信号的减少的 RA,显型连接了到 UBE3A 活动过度,我们的调查结果介绍 ASD 病原学的新远景并且对这逐渐地流行的疾病便于治疗学的开发的一个模式。 | Xingxing Xu Chuanyin Li Xiaobo Gao Kun Xia Hui Guo Yali Li ZijianHao Lei Zhang Daming Gao Chenfan Xu Huatai Xu Zhi-Qi Xiong Zilong Qiu Ling Mei Xiaoduo Xie Kangcheng Ruan Ronggui Hu | 2018 | Cell Research2018，28，1： | 13 |
| 6 | Spatial and temporal variation of runoff of Red River Basin in Yunnan显示文摘这篇论文学习红河盆的流量的变化并且讨论“走廊障碍”的影响由基于每月的降水使用 GIS 和统计方法的流量的变化上的山谷和山的功能。 | LI Yungang HE Daming YE Changqing | 2008 | Journal of Geographical Sciences2008，18，3： | 12 |
| 7 | Effects of surface chemical properties of activated coke on selective catalytic reduction of NO with NH_3 over commercial coal-based activated coke显示文摘Surface chemical properties of typical commercial coal-based activated cokes were characterized by Xray photoelectron spectroscopy(XPS) and acid-base titration, and then the influence of surface chemical properties on catalytic performance of activated cokes of NO reduction with NH3 was investigated in a fixed-bed quartz micro reactor at 150 ℃. The results indicate that the selective catalytic reduction(SCR) activity of activated cokes with the increase of its surface acidic sites and oxygen content,obviously, a correlation between catalytic activity and surface acidic sites content by titration has higher linearity than catalytic activity and surface oxygen content by XPS. While basic sites content by acid-base titration have not correlation with SCR activity. It has been proposed that surface basic sites content measured by titration may not be on adjacent of acidic surface oxides and then cannot form of NO2-like species, thus the reaction of reduction of NO with NH3 have been retarded. | Xie Wei Sun Zhongchao Xiong Yinwu Li Lanting Wu Tao Liang Daming | 2014 | International Journal of Mining Science and Technology2014，24，4： | 12 |
| 8 | A direct position determination method with combined TDOA and FDOA based on particle filter显示文摘The localization of a stationary transmitter using moving receivers is considered.The original Direct Position Determination(DPD) methods, with combined Time Difference of Arrival(TDOA) and Frequency Difference of Arrival(FDOA), do not perform well under low Signal-toNoise Ratio(SNR), and worse still, the computation cost is difficult to accept when the computational capabilities are limited.To get better positioning performance, we present a new DPD algorithm that proves to be more computationally efficient and more precise for weak signals than the conventional approach.The algorithm partitions the signal received with the same receiver into multiple non-overlapping short-time signal segments, and then uses the TDOA, the FDOA and the coherency among the short-time signals to locate the target.The fast maximum likelihood estimation, one iterative method based on particle filter, is designed to solve the problem of high computation load.A secondary but important result is a derivation of closed-form expressions of the Cramer-Rao Lower Bound(CRLB).The simulation results show that the algorithm proposed in this paper outperforms the traditional DPD algorithms with more accurate results and higher computational efficiency, and especially at low SNR, it is more close to the CRLB. | Zhiyu LU Bin BA Jianhui WANG Wenchao LI Daming WANG | 2018 | Chinese Journal of Aeronautics2018，31，1： | 11 |
| 9 | Large eddy simulation and proper orthogonal decomposition analysis of turbulent flows in a direct injection spark ignition engine:Cyclic variation and effect of valve lift显示文摘Large eddy simulation(LES)is used to calculate the in-cylinder turbulent flow field in a direct injection spark ignition(DISI)engine.The computations are carried out for three different maximum valve lifts(MVL)and throughout 100 consecutive engine cycles.The simulated results as well as corresponding particle image velocimetry(PIV)measurement database are analyzed by the proper orthogonal decomposition(POD)method.Through a new developed POD quadruple decomposition the instantaneous in-cylinder flow fields are decomposed into four parts,named mean field,coherent field,transition field and turbulent field,respectively.Then the in-cylinder turbulent flow characteristics and cycle-to-cycle variations(CCV)are studied separately upon the four part flow fields.Results indicate that each part exhibits its specific characteristics and has close connection with others.The mean part contains more than 50%of the total kinetic energy and the energy cascade phenomenon occurs among the four part fields;the coherent field part possesses the highest CCV level which dominates CCV of the bulk flow.In addition,it is observed that a change in MVL affects significantly the in-cylinder flow behavior including CCV,especially for the coherent part.Furthermore,the POD analysis demonstrates that at least 25 sample cycles for the mean velocity and 50 sample cycles for the RMS velocity are necessary for obtaining converged and correct results in CCV. | QIN WenJin XIE MaoZhao JIA Ming WANG TianYou LIU DaMing | 2014 | Science China(Technological Sciences)2014，57，3： | 11 |
| 10 | Pollution assessment of heavy metals along the Mekong River and dam effects显示文摘在湄公河河盆的水文学政体,沉积和水质量的资源发展和变化吸引了大注意。这研究试图在这条国际河里在重金属的 transboundary 污染上提高学习。在这研究,八个采样地点被选择沿着湄公河河的主流收集床沙样品。另外, 5 个重金属元素的内容和他们沿着河的主流的空间可变性被分析。geoaccumulation 索引(Igeo ) 和潜在的生态的风险分析被采用在湄公河河的主流估计重金属污染地位。结果证明重金属元素 Zn 的平均内容是 91.43 mg/kg , Pb 是 41.85 mg/kg ,并且这是在上面的湄公河的床沙的 21.84 mg/kg 河,比那些高, Zn 68.17 mg/kg , Pb 28.22 mg/kg ,作为 14.97 mg/kg )在更低的湄公河。在更低的湄公河的 Cr 的平均内容是 418.86 mg/kg,比那高在上面的湄公河(42.19 mg/kg ) 。Luang Prabang 与 422.90 mg/kg 与 762.93 mg/kg 和 Pakse 有很高的 Cr 集中。8 个采样地点的在所有的 Cu 的集中是类似的,除了在有 11.70 mg/kg 的 Jiajiu 和有 7.00 mg/kg 的 Jiebei。当时, geoaccumulation 索引的结果表明污染由 Zn 和 Pb 引起了 Pb 并且这多于由在上面的湄公河的 Zn 的那些。Cr 是在更低的湄公河的主要污染物质,特别在 Luang Prabang 和 Pakse。细微污染与作为也发生在 Pakse。潜在的生态的风险索引显示在湄公河河的主流的重金属的潜在的生态的风险是低的。我们主张水质量的污染和在床沉积的重金属的污染在湄公河由矿物质资源或 geochemical 背景价值的采矿引起了没被播送从对更低的湄公河上面因为沿着河的水库沉积和冲淡。 | FU Kaidao SU Bin HE Daming LU Xixi SONG Jingyi HUANG Jiangcheng | 2012 | Journal of Geographical Sciences2012，22，5： | 10 |
| 11 | Ferrites boosting photocatalytic hydrogen evolution over graphitic carbon nitride: a case study of(Co, Ni)Fe_2O_4 modification显示文摘The charge carrier separation and surface catalytic redox reactions are of primary importance as elementary steps in photocatalytic hydrogen evolution. In this study, both of these two processes in photocatalytic hydrogen evolution over graphitic carbon nitride(g-C_3N_4) were greatly promoted with the earth-abundant ferrites(Co,Ni)Fe_2O_4modification. Co Fe_2O_4 was further demonstrated to be a better modifier for g-C_3N_4 as compared to Ni Fe_2O_4,due to the more efficient charge carrier transfer as well as superior surface oxidative catalytic activity. When together loading Co Fe_2O_4 and reductive hydrogen production electrocatalyst Pt onto g-C_3N_4, the obtained Pt/g-C_3N_4/Co Fe_2O_4 photocatalyst achieved visible-light(λ>420 nm) hydrogen production rate 3.5 times as high as Pt/g-C_3N_4, with the apparent quantum yield reaching 3.35 % at 420 nm. | Jie Chen Daming Zhao Zhidan Diao Miao Wang Shaohua Shen | 2016 | Science Bulletin2016，61，4： | 10 |
| 12 | Toxicity detection of sodium nitrite,borax and aluminum potassium sulfate using electrochemical method显示文摘Based on the inhibition effect on the respiratory chain activity of microorganisms by toxicants,an electrochemical method has been developed to measure the current variation of a mediator in the presence of microorganisms contacted with a toxicant.Microelectrode arrays were adopted in this study,which can accelerate the mass transfer rate of an analyte to the electrode and also increase the total current signal,resulting in an improvement in detection sensitivity.We selected Escherichia coli as the testee and the standard glucoseglutamic acid as an exogenous material.Under oxygen restriction,the experiments in the presence of toxicant were performed at optimum conditions(solution pH 7.0,37°C and reaction for 3 hr).The resulting solution was then separated from the suspended microorganisms and was measured by an electrochemical method,using ferricyanide as a mediator.The current signal obtained represents the reoxidation of ferrocyanide,which was transformed to inhibiting efficiency,IC 50,as a quantitative measure of toxicity.The IC 50 values measured were 410,570 and 830mg/L for sodium nitrite,borax and aluminum potassium sulfate,respectively.The results show that the toxicity sequence for these three food additives is consistent with the value reported by other methods.Furthermore,the order of damage degree to the microorganism was also observed to be:sodium nitrite > borax > aluminum potassium sulfate > blank,according to the atomic force microscopy images of E.coli after being incubated for 3 hr with the toxic compound in buffer solutions.The electrochemical method is expected to be a sensitive and simple alternative to toxicity screening for chemical food additives. | Dengbin Yu Daming Yong Shaojun Dong | 2013 | Journal of Environmental Sciences2013，25，4： | 9 |
| 13 | Trends in precipitation over the low latitude highlands of Yunnan, China显示文摘在西南中国的云南的低纬度高地的降水政体服从于在东方亚洲夏天季风和印度夏天之间的相互作用表面山志学的季风,和影响。在它的空间、时间的模式的变化的理解着急地为气候变化设计,水文学影响建模,和地区性、下游的水资源管理被需要。用在最后几十年( 1950s2007 )的低纬度高地的每日的 降水记录, 降水的一个时间系列索引,包括年度 降水,多雨的天的数字,吝啬的年度 降水紧张,雨季的发作的日期, 降水的度和时期季节的集中,最高1天、3天、7天的 降水,和 降水在不同紧张上面为 降水多雨的天总计并且数(例如 10 公里, 25 公里一没有趋势的预先增白的 Mann-Kendall 趋势测试然后被用来检测时间系列数据的趋势。结果证明在年度降水和越过低纬度高地的降水趋势的强壮的季节的区别没有重要趋势。弹簧和冬季正在变得更湿,夏天正在变得更干燥。秋天在东方正在变得更干燥并且在西方更湿。作为后果,降水的 seasonality 稍微正在变弱。雨季和最高的降水的时期的开始趋于更早。同时,低纬度高地也见证不太多雨的天,更强烈的降水,稍微更长中等、重的降水事件,和更经常的极端降水事件。另外,降水趋势的地区性的区别是显著的。这些变化可以与东方亚洲夏天季风变弱并且南方亚洲人夏天季风,以及特殊多山的地面的走廊障碍效果加强被联系。然而,包含的物理机制仍然需要以后被揭开。 | FAN Hui | 2013 | Journal of Geographical Sciences2013，23，6： | 9 |
| 14 | Analysis and prediction of sediment trapping efficiencies of the reservoirs in the mainstream of the Lancang River显示文摘存储的水和水库套住的沉积在下游的水路环境上导致物理、化学、生态的效果。关于水库沉积的量的研究是钥匙估计它的环境影响。在位于 Manwan 水库的 upstream 和 downstream 的计量车站在 39 年获得的沉积负担数据被用来估计 Manwan 水坝的套住的效率(TE ) 。TE 价值当时与用修改 Brune 和 Siyam 模型的估计相比。结果显示那:(1 ) 计量数据估计的 Manwan 水坝的 TE 是 60.48% ,并且两个都, TE 值由修改 Brune 计算了, Siyam 模型是 60.03% 。近似 TE 价值显示修改 Brune 和 Siyam 模型能被用来在 Lancang 河的主流作为 Manwan 水库与类似的存储能力预报另外的水库的 TE;(2 ) Gongguoqiao, Dachaoshan 和 Jinghong 水坝的 TE 价值是大约 30.23% , 66.05% 和 63.50% 由修改 Brune 模型估计了,并且 38.81% , 63.97% 和 62.30% 由修改 Siyam 当模特儿。在论文采用的结果和方法论能也被用来在西南的中国在另外的河盆估计 TE。 | FU KaiDao HE DaMing | 2007 | Chinese Science Bulletin2007，52，A02： | 9 |
| 15 | Climatic control of plant species richness along elevation gradients in the Longitudinal Range-Gorge Region显示文摘在纵的范围峡区域(LRGR ) 在种类丰富探索举起坡度并且评估气候的变量和区域怎么可以解释种类丰富的模式, 5 座山被选择。根据举起,山,种类丰富,区域的价值和气候的变量的维的坡度在每 100 m 地区被计算。在沿着举起坡度的种子工厂种类丰富和气候的变量和区域之间的关系被分析。结果显示出那:(1 ) 种类丰富的 Elevational 模式不是制服并且能被划分在到二种类型。种类丰富的价值在低地是更高的然后与在热带山增加举起 monotonically 减少。种类丰富在副热带的山在举起坡度的更低的一半向高价值与偏爱有单峰的模式。(2 ) 种类密度的模式在沿着举起坡度的种类丰富与那一样。(3 ) 在气候变量之中,实际土壤水分蒸发蒸腾损失总量(AET ) 与种类丰富作为水精力平衡的大小有强壮的关系。在种类丰富的衰落在副热带的山的低地由于更高的温度和更少的降水。 | LIU Yang ZHANG YiPing HE DaMing CAO Min ZHU Hua | 2007 | Chinese Science Bulletin2007，52，A02： | 9 |
| 16 | Surface chemical properties and pore structure of the activated coke and their effects on the denitrification activity of selective catalytic reduction显示文摘In order to study the mechanism of selective catalytic reduction of activated coke to remove NO in low-temperature flue gas and provide some theoretical basis for the development of related technologies.The pore sizedistribution and BET specific surface area of AC were obtain by data analyzing of N2 adsorption/desorption isotherm at -196 ℃ and carbon matrix and surface chemistry of virgin activated coke samples were characterized by acid-base titration and XPS.The process of selective catalytic reduction of activated coke (AC) samples with NH3 as reducing agent was studied in a fixed bed reactor at 150 ℃.The result shows that pore size distribution or BET specific surface of activated cokes have not correlation with denitrification activity for SCR.The NO reduction activities of the activated cokes are apparent to increase with their surface oxygen element content and total amount of acidic sites.Obviously there is good linear relationship between the NH3 adsorption capacity and activity for SCR with linear correlation coefficient 0.943.It has been presented that adsorption of NH3 on acidic functional groups in the edge of large polycyclic aromatic ring of activated coke is key rate controlling step in the SCR heterogeneous catalytic reaction. | Wei Xie Daming Liang Lanting Li Sijian Qu Wu Tao | 2019 | International Journal of Coal Science & Technology2019，6，4： | 8 |
| 17 | Water Cooperation Priorities in the Lancang-Mekong River Basin Based on Cooperative Events Since the Mekong River Commission Establishment显示文摘The Lancang-Mekong River has attracted much attention from researchers, but the cooperation on water issues in this river basin has been limited, even after the establishment of the Mekong River Commission(MRC). Cooperation on water resources has been determined as one of the key priority areas in the Lancang-Mekong Cooperation Mechanism, but there are no details of targets. In order to establish the priorities of water cooperation under the mechanism, we adopted nine categories to classify the objectives of 87 water cooperation events based on the ‘Lancang-Mekong Water Cooperative Events Database' from 1995 to 2015. Based on the occurrence of cooperative events, cooperative objectives, cooperative scales, and approaches to cooperation, we conducted statistical, correlation, and text analyses. Our analyses indicated the following results: under the impact of economic conditions inside and outside the river basin, full cooperation appeared more difficult than bilateral and multilateral cooperation. Each of the partners adopted different preferences for cooperation targets. Cooperation with more definite objectives was easier to establish than cooperation with broader and more complex objectives. The potential objectives for water cooperation were navigation, hydropower, joint management, data sharing, flood control and water use. Because hydropower development is controversial, and because water cooperation is avoided by most existing regional cooperation mechanisms due to its complexity, we suggest the following priority areas for water cooperation in the Lancang-Mekong River Basin. 1) Navigation and flood control/drought relief are attractive objectives for all the riparian countries across the whole watershed. 2) Data sharing should be a priority for cooperation in the watershed due to its laying the foundation for the equitable and reasonable utilization of transboundary waters. 3) Hydropower is an objective best implemented mainly through bilateral cooperation, and on tributaries. | FENG Yan WANG Wenling SUMAN Daniel YU Shiwei HE Daming | 2019 | Chinese Geographical Science2019，29，1： | 8 |
| 18 | Validation of dynamic cavitation model for unsteady cavitating flow on NACA66显示文摘Unsteady cavitating flow is extremely complicated and brings more serious damages and unignorable problems compared with steady cavitating flow.CFD has become a practical way to model cavitation;however,the popularly used full cavitation model cannot reflect the pressure-change that the bubble experiences during its life path in the highly unsteady flow like cloud cavitating.Thus a dynamic cavitation model(DCM)is proposed and it has been considered to have not only the first-order pressure effects but also zero-order effect and can provide greater insight into the physical process of bubble producing,developing and collapsing compared to the traditional cavitation model.DCM has already been validated for steady cavitating flow,and the results were reported.Furthermore,DCM is designed and supposed to be more accurate and efficient in modeling unsteady cavitating flow,which is also the purpose of this paper.The basic characteristic of the unsteady cavitating flow,such as the vapor volume fraction distribution and the evolution of pressure amplitude and frequency at different locations of the hydrofoil,are carefully studied to validate DCM.It is found that not only these characteristics mentioned above accord well with the experimental results,but also some detailed transient flow information is depicted,including the re-entrant jet flow that caused the shedding of the cavity,and the phenomenon of two-peak pressure fluctuation in the vicinity of the cavity closure in a cycle.The numerical results validate the capability of DCM for the application of modeling the complicated unsteady cavitating flow. | ZHANG XiaoBin ZHANG Wei CHEN JianYe QIU LiMin SUN DaMing | 2014 | Science China(Technological Sciences)2014，57，4： | 8 |
| 19 | Investigation on regenerator temperature inhomogeneity in Stirling-type pulse tube cooler显示文摘Regenerator is one of the most crucial components to pulse tube cooler (PTC) and thermoacoustic engine. As such regenerator is scaled up to high-power, the thermal and hydrodynamic communication transverse to the acoustic axis gets weaker and weaker. Under this condition, any unsymmetric factor could cause serious instability to the cooler or engine, which degrades their performance. Investigation has been carried out on a high-power two-stage thermal-coupled U-shape Stirling-type PTC. By detailed circumferential temperature measurements along the middle heat exchanger and second stage regen-erator, a kind of temperature inhomogeneity caused by unsymmetric pre-cooling effect of inter-stage thermal bridge was found in the lower part of the regenerator of the PTC. The temperature inhomoge-neity originating from the middle heat exchanger of the second stage regenerator amplified itself in the lower part of the regenerator and then internal streaming formed. The maximal radial temperature dif-ference could reach 30―40 K. Experimental results show that the temperature inhomogeneity intensi-fies with increased pre-cooling power and its direction can be reversed by changing the pre-cooling effect of the first stage PTC to heating effect by using external thermal load. This research shows that it is important to maintain the heating or cooling effects of heat exchangers uniform in high-power re-generative coolers and engines. | SUN DaMing MARC Dietrich GUENTER Thummes Qiu LiMin | 2009 | Chinese Science Bulletin2009，54，6： | 7 |
| 20 | Climatic difference in dry and wet season under effect of the Longitudinal Range-Gorge and its influence on transboundary river runoff显示文摘 | YOU Weihong DUAN Changchun HE Daming | 2006 | Chinese Science Bulletin2006，51，B11： | 7 |
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