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| 1 | Non-coding RNAs and other determinants of neuroinflammation and endothelial dysfunction:regulation of gene expression in the acute phase of ischemic stroke and possible therapeutic applications显示文摘Ischemic stroke occurs under a variety of clinical conditions and has different pathogeneses,resulting in necrosis of brain parenchyma.Stroke pathogenesis is characterized by neuroinflammation and endothelial dysfunction.Some of the main processes triggered in the early stages of ischemic damage are the rapid activation of resident inflammatory cells(microglia,astrocytes and endothelial cells),inflammatory cytokines,and translocation of intercellular nuclear factors.Inflammation in stroke includes all the processes mentioned above,and it consists of either protective or detrimental effects concerning the“polarization”of these processes.This polarization comes out from the interaction of all the molecular pathways that regulate genome expression:the epigenetic factors.In recent years,new regulation mechanisms have been cleared,and these include non-coding RNAs,adenosine receptors,and the activity of mesenchymal stem/stromal cells and microglia.We reviewed how long non-coding RNA and microRNA have emerged as an essential mediator of some neurological diseases.We also clarified that their roles in cerebral ischemic injury may provide novel targets for the treatment of ischemic stroke.To date,we do not have adequate tools to control pathophysiological processes associated with stroke.Our goal is to review the role of non-coding RNAs and innate immune cells(such as microglia and mesenchymal stem/stromal cells)and the possible therapeutic effects of their modulation in patients with acute ischemic stroke.A better understanding of the mechanisms that influence the“polarization”of the inflammatory response after the acute event seems to be the way to change the natural history of the disease. | Mario Daidone Marco Cataldi Antonio Pinto Antonino Tuttolomondo | 2021 | Neural Regeneration Research2021，16，11： | 9 |
| 2 | Survivin as a target for new anticancer interventions 显示文摘 | ZAFFARONI N PENNATI M DAIDONE M G | 2005 | J Cell Mol Med2005，9，2： | 1 |
| 3 | Survivin expression and resistance to anticancer treatments: perspectives for new therapeutic interven- tions显示文摘 | Zaffaroni N Daidone M G | 2002 | Drug Resist Updat2002，5，2： | 1 |
| 4 | Survivin as a target for new anticancer interventions显示文摘 | Pennati M Daidone MG | 2005 | Cell Mol Med2005，9，： | 1 |
| 5 | Survivin as a target for new anticancerinterventions显示文摘 | Zaffaroni N Pennati M Daidone MG | 2005 | Cell Mol Med2005，9，2： | 1 |
| 6 | Survivin expression and resistance to anticancer treatment:perspectives for new therapeutic interventions显示文摘 | Zaffaroni N Daidone MG | 2002 | Drug Resist Updat2002，5，2： | 1 |
| 7 | Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer显示文摘 | Daidone MG Costa A Frattini M | 2004 | Cancer Res2004，64，2： | 1 |
| 8 | survivin as a target for new anticancer interventions显示文摘 | Nadia Zaffaroni Marzia Pennati Maria Grazia Daidone | 2005 | J Cell Mol Med2005，9，2： | 1 |
| 9 | Modulation of angiogenesis-related proteins synthesis by sodium butyrate in colon cancer cell line HT29显示文摘 | Pellizzaro C Coradini D Daidone MG | 2002 | Carcinogenesis2002，23，5： | 1 |
| 10 | The Bcl-2 protein:a prognostic indicator strongly related to p53 protein in lymph node-negative breast cancer patients显示文摘 | Venereoni S Daidone M G | 1994 | J Natl Cancer Inst1994，86，7： | 1 |
| 11 | The Bcl-2 protein:a prognostic indicator strongly related to p53 protein in lymph node-negative breast cancer patients显示文摘 | Silvestrini R Veneroni S Daidone MG | | 0，，： | 1 |
| 12 | Survivin expression and resistance to anticancer treatments: perspectives for new therapeutic intervention显示文摘 | Zaffaroni N Daidone MG | 2002 | Drug Resist Updat2002，5，2： | 1 |
| 13 | Investigating the accessibility of the closed domain conformation of citrate synthase using essential dynamics sampling显示文摘 | Daidone I Roccatano D Hayward S | 2004 | J Mol Biol2004，339，： | 1 |
| 14 | Survivin as a target for new anticancer interventions 显示文摘 | Zaffaroni N Pennati M Daidone MG | 2005 | Cell Mol Med2005，9，： | 1 |
| 15 | Survivin as a target for new anticancer interventions显示文摘 | Zaffaroni N Pennati M Daidone MG | 2005 | J Cell Mol Med2005，9，2： | 1 |
| 16 | The Bcl-2 protein:a prognostic indicator strongly related to p53 protein in lymph node-negative breast cancer patients 显示文摘 | Silvestrini R Veneroni S Daidone MG | 1994 | J Natl Cancer Inst1994，86，7： | 1 |
| 17 | Introduction to can- cer biobanking : why, where, how? 显示文摘 | Paradiso A Daidone MG Riegman P | 2011 | Biopreserv Biobank2011，9，2： | 1 |
| 18 | Survivin as a target for new anticancer interventions显示文摘 | Zaffaroni N Pennati M Daidone M G | 2005 | J Cell Mol Med2005，9，2： | 1 |
| 19 | Survivin as a target for new anticancer interventions 显示文摘 | Zaffaroni N Pennati M Daidone MG | 2005 | J Cell Mol Med2005，9，2： | 1 |
| 20 | Survivin as a target for new anticancer interventions 显示文摘 | Zaffaroni N Pennati M Daidone MG | 2005 | J Cell Mol Med2005，9，2： | 1 |
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