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| 1 | Endoscopic retrograde cholangiography for pediatric choledocholithiasis: Assessing the need for endoscopic intervention显示文摘AIM:To assess pediatric patients for choledocholithiasis.We applied current adult guidelines to identify predictivefactors in children.METHODS:A single-center retrospective analysis was performed at a tertiary children's hospital.We evaluated 44 consecutive pediatric patients who underwent endoscopic retrograde cholangiography(ERCP) for suspected choledocholithiasis.Patients were stratified into those with common bile duct stones(CBDS) at ERCP vs those that did not using the American Society of Gastrointestinal Endoscopy(ASGE) guidelines(Very Strong and Strong criteria) for suspected CBDS.RESULTS:CBDS were identified in 84% at the time of ERCP.Abdominal ultrasound identified CBDS in 36% of patients.Conjugated bilirubin ≥ 0.5 mg/d L was an independent risk factor for CBDS(P = 0.003).The Very Strong(59.5%) and Strong(48.6%) ASGE criteria identified the majority of patients(P = 0.0001).A modified score using conjugated bilirubin had a higher sensitivity(81.2% vs 59.5%) and more likely to identify a stone than the standard criteria,odds ratio of 25.7 compared to 8.8.Alanine aminotransferase and gamma-glutamyl transferase values identified significant differences in a subset of patients with odds ratio of 4.1 and 3.25,respectively.CONCLUSION:Current adult guidelines identified the majority of pediatric patients with CBDS,but specific pediatric guidelines may improve detection,thus decreasing risks and unnecessary procedures. | Douglas S Fishman Bruno P Chumpitazi Isaac Raijman Cynthia Man-Wai Tsai E O’Brian Smith Mark V Mazziotti Mark A Gilger | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，11： | 6 |
| 2 | Efficacy of pancreatoscopy for pancreatic duct stones:A systematic review and meta-analysis显示文摘BACKGROUND Pancreatic duct stones can lead to significant abdominal pain for patients.Per oral pancreatoscopy(POP)-guided intracorporal lithotripsy is being increasingly used for the management of main pancreatic duct calculi(PDC)in chronic pancreatitis.POP uses two techniques:Electrohydraulic lithotripsy(EHL)and laser lithotripsy(LL).Data on the safety and efficacy are limited for this procedure.We performed a systematic review and meta-analysis with a primary aim to calculate the pooled technical and clinical success rates of POP.The secondary aim was to assess pooled rates of technical success,clinical success for the two individual techniques,and adverse event rates.AIM To perform a systematic review and meta-analysis of POP,EHL and LL for management of PDC in chronic pancreatitis.METHODS We conducted a comprehensive search of multiple electronic databases and conference proceedings including PubMed,EMBASE,Cochrane,Google Scholar and Web of Science databases(from 1999 to October 2019)to identify studies with patient age greater than 17 and any gender that reported on outcomes of POP,EHL and LL.The primary outcome assessed involved the pooled technical success and clinical success rate of POP.The secondary outcome included the pooled technical success and clinical success rate for EHL and LL.We also assessed the pooled rate of adverse events for POP,EHL and LL including a subgroup analysis for the rate of adverse event subtypes for POP:Hemorrhage,post-endoscopic retrograde cholangiopancreatography pancreatitis(PEP),perforation,abdominal pain,fever and infections.Technical success was defined as the rate of clearing pancreatic duct stones and clinical success as the improvement in pain.Randomeffects model was used for analysis.Heterogeneity between study-specific estimates was calculated using the Cochran Q statistical test and I2 statistics.Publication bias was ascertained,qualitatively by visual inspection of funnel plot and quantitatively by the Egger test.RESULTS A total of 16 studies including 383 patients met the inclusion criteria.The technical success rate of POP was 76.4%(95%CI:65.9-84.5;I2=64%)and clinical success rate was 76.8%(95%CI:65.2-85.4;I2=66%).The technical success rate of EHL was 70.3%(95%CI:57.8-80.3;I2=36%)and clinical success rate of EHL was 66.5%(95%CI:55.2-76.2;I2=19%).The technical success rate of LL was 89.3%(95%CI:70.5-96.7;I2=70%)and clinical success rate of LL was 88.2%(95%CI:66.4-96.6;I2=77%).The incidence of pooled adverse events for POP was 14.9%(95%CI:9.2-23.2;I2=49%),for EHL was 11.2%(95%CI:5.9-20.3;I2=15%)and for LL was 13.1%(95%CI:6.3-25.4;I2=31%).Subgroup analysis of adverse events showed rates of PEP at 7%(95%CI:3.5-13.6;I2=38%),fever at 3.7%(95%CI:2-6.9;I2=0),abdominal pain at 4.7%(95%CI:2.7-7.8;I2=0),perforation at 4.3%(95%CI:2.1-8.4;I2=0),hemorrhage at 3.4%(95%CI:1.7-6.6;I2=0)and no mortality.There was evidence of publication bias based on funnel plot analysis and Egger’s test.CONCLUSION Our study highlights the high technical and clinical success rates for POP,EHL and LL.POP-guided lithotripsy could be a viable option for management of chronic pancreatitis with PDC. | Syed M Saghir Harmeet S Mashiana Babu P Mohan Banreet S Dhindsa Amaninder Dhaliwal Saurabh Chandan Neil Bhogal Ishfaq Bhat Shailender Singh Douglas G Adler | 2020 | World Journal of Gastroenterology2020，26，34： | 5 |
| 3 | Miniature reeonfigurable three-dimensional fractal tree antennas 显示文摘 | Joshua S P Douglas H W | 2004 | IEEE Trans on Antennas Propagat2004，52，8： | 1 |
| 4 | Increased subclinical atherosc-lerosis in young adults with metabolic syndrome:the bogalusa heart study显示文摘 | Tzou W Douglas P Srinivasan S | 2005 | J Am Coll Cardiol2005，46，3： | 1 |
| 5 | Assessing the impact of country of origin on product evaluations: A new methodological perspective 显示文摘 | Johansson J K Douglas S P Nonaka I | 1985 | Journal of Marketing Research1985，22，4： | 1 |
| 6 | The relationship between atopy and chronic rhinosinusitis显示文摘 | Robinson S Douglas R Wormald P J | 2006 | Am J Rhinol2006，20，6： | 1 |
| 7 | Glucagon-like peptide 2:A nutrientresponsive gut growth factor显示文摘 | Douglas G B Yvette P Barbara S | 2001 | The Journal of Nutrition Bethesda2001，131，3： | 1 |
| 8 | Complex hygrothermal effects on the glass transition of an epoxy amine thermoset 显示文摘 | Choi S Douglas E P | 2010 | ACS Appl Mater Inter2010，2，3： | 1 |
| 9 | Introducing Food Fraud including translation and interpretation to Russian Korean,and Chinese languages显示文摘 | John S Douglas C M Hyeonho P | 2015 | Food Chemistry2015，189，12： | 1 |
| 10 | Membrane transport and cytokinin action in root hairs of Medicago sativa 显示文摘 | Silverman F P Assiamah A A Douglas S B | 1998 | Planta1998，205，： | 1 |
| 11 | Exaggerated heart rate oscillations during two meditation techniques 显示文摘 | Peng C-K and Mietus J E and Liu Y and Khalsa G and Douglas P S and Benson H and Goldberger A L | 1999 | Int J Cardiol:1999，70，： | 1 |
| 12 | Trend and variability of shoreline position显示文摘 | Galgano F A Douglas B C Leatherman S P | 1998 | Journal of Coastal Research1998，，26： | 1 |
| 13 | Consumer world-mindedness and attitudes toward product positioning in advertising:an examination of global versus foreign versus local positioning显示文摘 | Nijssen E J Douglas S P | 2011 | Journal of International Marketing2011，19，3： | 1 |
| 14 | Auditory distance perception in humans:a summary of past and present research显示文摘 | ZAHORIK P DOUGLAS S B ADELBERT W B | 2005 | Acustica2005，91，3： | 1 |
| 15 | A novel parsley 4CL1 cis-element is required for developmentally regulated expression and protein-DNA complex formation 显示文摘 | Neutaedter D A Lee S P Douglas C J | 1999 | Plant J1999，18，： | 1 |
| 16 | Sensor for transient heat flux at a surface with throughflow 显示文摘 | Polat S Heiningen A R P V Douglas W J M | 1991 | International Journal of Heat and Mass Transfer1991，34，6： | 1 |
| 17 | Transgenic ex- pression of green fluorescence protein can cause dilated cardimyophthy显示文摘 | Huang W Y Aramburu J Douglas P S | 2000 | Nat Med2000，6，5： | 1 |
| 18 | Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy显示文摘 | Huang W Aramburu J Douglas P S | | 0，，05： | 1 |
| 19 | Extraction of nimbin form neem seed using supercritical CO2 and supercritical CO2-methanol mixtture显示文摘 | Tonthubthimthong P Douglas P L Douglas S | 2004 | J of Supercritical Fluids2004，30，： | 1 |
| 20 | Human lymphocytes express substance P and its receptor 显示文摘 | Lai J P Douglas S D Ho W Z | 1998 | J Neuroimmunol1998，86，： | 1 |
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