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| 1 | Effectiveness of Helicobacter pylori eradication in the treatment of early-stage gastric mucosa-associated lymphoid tissue lymphoma:An up-to-date meta-analysis显示文摘BACKGROUND Gastric mucosa-associated lymphoid tissue(MALT)lymphoma(GML)is usually a low-grade B-cell neoplasia strongly associated with Helicobacter pylori(H.pylori)-induced chronic gastritis.Clinical practice guidelines currently recommend H.pylori eradication as the preferred initial treatment for early-stage GML.To determine the practical effect of bacterial eradication as the sole initial therapy for early-stage GML,an updated analysis and review of available evidence is imperative.AIM To perform a meta-analysis to assess the rate of complete remission(CR)of H.pylori-positive early-stage GML following bacterial eradication.METHODS We performed independent,computer-assisted literature searches using the PubMed/MEDLINE,Embase,and Cochrane Central databases through September 2022.Prospective and retrospective observational studies evaluating the CR of early-stage GML following bacterial eradication in H.pylori-positive patients.The risk of bias was assessed using Joanna Briggs Institute(JBI)Critical Appraisal Tools.The pooled estimate of the complete histopathological remission rate and respective confidence intervals(95%CI)were calculated following the random-effects model.Heterogeneity and inconsistency were assessed using Cochran’s Q test and I2 statistic,and heterogeneity was defined as P<0.01 and I²>50%,respectively.Subgroup and meta-regression analyses were conducted to explore potential sources of heterogeneity.RESULTS The titles and abstracts of 1576 studies were screened;96 articles were retrieved and selected for full-text reading.Finally,61 studies were included in the proportional meta-analysis(P-MA).Forty-six were prospective and fifteen were retrospective uncontrolled,single-arm,observational studies.The overall risk of bias was low to moderate in all but a single report,with an average critical appraisal score across all studies of 79.02%.A total of 2936 H.pylori-positive early-stage GML patients,in whom H.pylori was successfully eradicated,were included in the analysis.The pooled CR of H.pylori-positive early-stage GML after bacterial eradication was 75.18%(95%CI:70.45%-79.91%).P-MA indicated the substantial heterogeneity in CR reported across studies(I2=92%;P<0.01).Meta-regression analysis identified statistically significant effect modifiers,including the proportion of patients with t(11;18)(q21;q21)-positive GML and the risk of bias in each study.CONCLUSION Comprehensive synthesis of available evidence suggests that H.pylori eradication is effective as the sole initial therapy for early-stage GML.Although the substantial heterogeneity observed across studies limits the interpretation of the pooled overall CR,the present study is a relevant to informing clinical practice. | Fabian Fellipe Bueno Lemos Caroline Tianeze de Castro Mariana Santos Calmon Marcel Silva Luz Samuel Luca Rocha Pinheiro Clara Faria Souza Mendes dos Santos Gabriel Lima Correa Santos Hanna Santos Marques Henrique Affonso Delgado Kádima Nayara Teixeira Cláudio Lima Souza Márcio Vasconcelos Oliveira Fabrício Freire de Melo | 2023 | World Journal of Gastroenterology2023，29，14： | 2 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | In vitro hepatic differentiation of human bone mam-w mesenchymal stem cells under differential exposure to liver-specific factors显示文摘 | Chivu M Dima SO Stancu CI | 2009 | Transl Res2009，154，3： | 1 |
| 4 | Modeling out of plane behavior of URM walls retrofitted with fiber composites 显示文摘 | Velazquez Dimas J Ehsani M R | 2000 | Joumal of Composites for Con- struction2000，4，4： | 1 |
| 5 | Bilat- eral blindness in endogenous endophthalmitis with fulmi- nant course--a clinical case 显示文摘 | Puianu M Stefnescu -Dima A Rdulescu M et af | 2013 | Oftalmologia2013，57，1： | 1 |
| 6 | In vitro hepatic differentiation of human hone marrow mesenchymal stem cells under differential exposure to liver-specific factors显示文摘 | Chivu M Dima SO Stancu CI | 2009 | Transl Res2009，154，3： | 1 |
| 7 | Reduction of vertical tail buffet response using active control 显示文摘 | Hauch R M Jacobs J H Dima C | 1996 | Journal of Aircraft1996，35，3： | 1 |
| 8 | Spectrophotometic Determination of Cysteine and/or Carbocysteine in a Mixture of Amino Acid,Shampoo,and Pharmaceutical Product Using p-Benzoquinone显示文摘 | Dimas A M Kelly C L Cassia T B V | 1999 | Talanta1999，50，5： | 1 |
| 9 | Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal adenocarcinoma显示文摘 | Tanase CP Dima S Mihai M | 2009 | J Mol Histol2009，40，1： | 1 |
| 10 | Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors显示文摘 | Antico Arciuch VG Russo MA Dima M | 2011 | Oncotarget2011，2，12： | 1 |
| 11 | High periostin expression correlates with aggressiveness in papillary thyroid carcinomas显示文摘 | Puppin C Fabbro D Dima M | 2008 | J Endocrinol2008，197，2： | 1 |
| 12 | Unconventional techniques for the extraction of bioactive compounds from various plants显示文摘 | GITIN L STOICA M DIMA C | 2013 | Journal of Agroalimentary Processes and Technologies2013，19，2： | 1 |
| 13 | In vitro hepatic differentiation of human bone marrow mesenchymal stem cells under differential exposure to liver-specific factors 显示文摘 | Chivu M Dima SO Stancu CI | 2009 | Transl Res2009，154，3： | 1 |
| 14 | Identification of a new transcriptional activity of mammalian Id proteins 显示文摘 | Bounphening M A Meinikova I N Dimas J | 1999 | Nucleic Acids Research1999，27，7： | 1 |
| 15 | 查看详情显示文摘 | Saroglou V Karioti A Rancic A Dimas K Koukoulitsa C Zervou M Skaltsa H | | 0，，： | 1 |
| 16 | Ion pair formation as a possible mechanism for the enhancement effect of Lauric acid on the transdermal permeation of ondansetron显示文摘 | DIMAS D A DALLAS P P REKKS D M | 2004 | Pharm Dev Technol2004，9，3： | 1 |
| 17 | Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal sdenocarcinoma显示文摘 | Tanase CP Dima S Mihai M | 2009 | J Mol Histol2009，40，1： | 1 |
| 18 | Reduction ofvertical tail buffet response using active control 显示文摘 | Hauch R M Jacobs J H Dima C | 1996 | Journal of Aircraft1996，33，3： | 1 |
| 19 | Immunohistochemical study of p185 HER2 and DF3 in primary breast cancer and correlation with CA-15-3 serum tumor marker显示文摘 | Dimas C Frangos-Plemenos M Kouskouni E | 2002 | Int J Gynecol Cancer2002，12，： | 1 |
| 20 | Immunohistochemical study of p185 HER2 and DF3 in primary breast cancer and correlation with CA--15--3 serum tumor marker显示文摘 | Dimas C Frangos-Plemenos M Kouskouni E | 2002 | Int J Gynecol Cancer2002，12，1： | 1 |
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