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| 1 | Efficacy of Gold Nanoparticles against Nephrotoxicity Induced by Schistosoma mansoni Infection in Mice显示文摘Objective In this study, the ameliorative effects of gold nanoparticles(gold NP) on the renal tissue damage in Schistosoma mansoni(S. mansoni)-infected mice was investigated. Methods High-resolution transmission electron microscopy was used for the characterization of NP. The gold NP at concentrations of 250, 500, and 1000 μg/kg body weight were inoculated into S. mansoni-infected mice. Results The parasite caused alterations in the histological architecture. Furthermore, it induced a significant reduction in the renal glutathione levels; however, the levels of nitric oxide and malondialdehyde were significantly elevated. The parasite also managed to downregulate KIM-1, NGAL, MCP-1, and TGF-β mR NA expression in infected animals. Notably, gold NP treatment in mice reduced the extent of histological impairment and renal oxidative damage. Gold NP were able to regulate gene expression impaired by S. Mansoni infection. Conclusion The curative effect of gold NP against renal toxicity in S. mansoni-infected mice is associated with their role as free radical scavengers. | Mohamed A Dkhil Mona F Khalil2 Amira A Bauom Marwa SM Dia Saleh A1-Qura | 2016 | Biomedical and Environmental Sciences2016，29，11： | 2 |
| 2 | Trends in polymer electrolytes for secondary batteries 显示文摘 | L Plomp J B J Veldhuis | 2000 | J Power Sources2000，88，： | 1 |
| 3 | Mineralogy and geochemistry of hydrothermal sediments from the serpentinite-hosted Saldanha hydrothermal field ( 36°34' N ; 33 ° 26' W) at MAR 显示文摘 | Dias A S Barriga F J | 2006 | Marine Geology2006，225，： | 1 |
| 4 | 显示文摘 | Portela M F | 1995 | J Catal1995，157，： | 1 |
| 5 | Availability of phosphorus in a Brazilian Oxisol cultivated with Eucalyptus after nine years as influenced by phosphorus-fertilizer source,rate and placement显示文摘 | DIAS L E FERNANDEZ J Q P BARROS N F | 2001 | Communications in soil science and plant analysis2001，32，78： | 1 |
| 6 | Cytotoxic flavone analogues of vitexicarpiu, a constituent of the leaves of Vitex negundo 显示文摘 | Dia F Chavez D Lee D | 2003 | J Nat Prod2003，66，6： | 1 |
| 7 | Effect of experimental conditions on cogasification of coal,biomass and plastics wastes with air/steam mixtures in a fluidized-bed system显示文摘 | PINTO F FRANCO C ANDRE R TAVARES C DIAS M GULYURTLU I CABRITA I | 2003 | Fuel2003，82，1517： | 1 |
| 8 | The effect of stirring and seeding on the AcPheLeuNH2 synthesis and crystallization in a reversed micellar system显示文摘 | FELICIANO A S DIAS A I PRAZERES D M F | 2000 | Enzy & Microb Tech2000，27，： | 1 |
| 9 | The coat-mix procedure using carbon fillers 显示文摘 | LUHLEICH H DIAS F J NICKEL H | 1997 | Carbon1997，35，： | 1 |
| 10 | Glucose overload in yolk has little effect on the long-term modulation of carbohydrate metabolic genes in zebrafish(Danio rerio)显示文摘 | Rocha F Dias J Engrola S | 2014 | The Journal of Experimental Biology2014，217，7： | 1 |
| 11 | 显示文摘 | Silva T F Dias J A C Maciel C G | 2013 | Catal Sci Technol2013，3，： | 1 |
| 12 | Enzymatic kinetic of cel- lulose hydrolysis-Inhibition by ethanol and cellobiose 显示文摘 | BEZERRA R M F DIAS A A | 2005 | Applied Biochemistry and Biotechnology2005，126，1： | 1 |
| 13 | Properties of Ni/YSZ porous cermets for SOFC by tape casting and coat-mix process 显示文摘 | SIMWONIS D THULEN H DIAS F J | 1999 | J Mater Proc Tech1999，92，93： | 1 |
| 14 | Intracardiac chocardiography guided device closore of atrial septal defects显示文摘 | Mullen M J Dias B F Walker F | 2003 | J Am Coll Cardiol2003，41，2： | 1 |
| 15 | Prognostic factors and out- come for nasopharyngeal carcinoma 显示文摘 | Farias T P Dias F L Lima R A | 2003 | Arch Otolalyngol Head Neek Surg2003，129，7： | 1 |
| 16 | 显示文摘 | Pavan F A Dias S L P Lima E C | 2008 | Dyes Pigments2008，76，： | 1 |
| 17 | Risk factors associated with sero-positivity to Toxoplasma gondii in captive neotropical felids from Brazil显示文摘 | Ramossilva J C Marvulo M F Dias R A | 2007 | Prey Vet Med2007，78，34： | 1 |
| 18 | Multiohjective genetic algorithms applied to solve optimization problems显示文摘 | Dias'A H F De vasconcelos J A | 2002 | IEEE Transactions on Magnetics2002，38，2： | 1 |
| 19 | Immobilization of Fe, Mn and Co tetraphenylporphyrin complexes in MCM-41 and their catalytic activity in cyclohexene oxidation reaction by hydrogen peroxide 显示文摘 | COSTA A A GHESTI G F MACEDO J L BRAGA V S SANTOS M M DIAS J A DIAS S C L | 2008 | J Mol Catal A: Chem2008，282，： | 1 |
| 20 | Vulnerability to stress, anxiety and depressive symptoms and metabolic control intype 2 dia- betes显示文摘 | Gois C Dias V V Raposo J F | 2012 | BMC Res Notes2012，5，： | 1 |
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