|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | AFP level and histologic differentiation predict the survival of patients with liver transplantation for hepatocellular carcinoma显示文摘BACKGROUND: In liver transplantation or resection for hepatocellular carcinoma (HCC), patient selection depends on morphological features. In patients with HCC, we performed a clinicopathological analysis of risk factors that affected survival after liver transplantation. METHODS: In 389 liver transplantations performed from 2004 to 2010, 102 were for HCC patients. Data were collected retrospectively from the Organ Transplantation Center Database. Variables were as follows: age, gender, preoperative alpha-fetoprotein (AFP) levels, Child-Pugh and MELD scores, prognostic staging criteria (Milan and UCSF), etiology, number of tumors, the largest tumor size, total tumor size, multifocality, intrahepatic portal vein tumor thrombosis, bilobarity, and histological differentiation. RESULTS: One hundred and two patients were evaluated. The 5-year overall survival rate was 56.5%. According to the UCSF criteria, 63% of the patients were within and 37% were beyond UCSF (P=0.03). Ten patients were excluded (one with fibrolamellary HCC and 9 because of early postoperative death without HCC recurrence), and 92 patients were assessed. The mean age of the patients was 56.5±6.9 years. Sixty-two patients underwent living donor liver transplantations. The mean follow-up time was 29.4±22.6 months. Fifteen patients (16.3%) died in the follow-up period due to HCC recurrence. Univariate analysis showed that AFP level, intrahepatic portal vein tumor thrombosis, histologic differentiation and UCSF criteria were significant factors related to survival and tumor recurrence. The 5-year estimated overall survival rate was 62.2% in allpatients. According to the UCSF criteria, and the 5-year overall survival rate was 66.7% within and 52.7% beyond the criteria (P=0.04). Multivariate analysis showed that AFP level and poor differentiation were independent factors. CONCLUSIONS: For proper patient selection in liver trans- plantation for HCC, prognostic criteria related to tumor biology (especially AFP level and histological differentiation) should be considered. Poor differentiation and higher AFP levels are indicators of poor prognosis after liver transplantation. | Onur Yaprak Murat Akyildiz Murat Dayangac Baha Tolga Demirbas Necdet Guler Gulen Bulbul Dogusoy Yildiray Yuzer Yaman Tokat | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 15 |
| 2 | 中英中小企业技术创新支持体系比较显示文摘比较中英两国中小企业技术创新的支持体系,可以看到中英两国都已经初步建立了财税和金融支持体系,但英国的体系更完善,支持的力度更大,覆盖面更宽,操作性更强,形式更丰富,效果更明显;在协同创新支持体系建设方面,英国的显著特点是以项目为载体,促进大学与企业的合作,中国主要通过行政机制来实现产学研的结合,缺乏自主合作、市场化推进的协作机制;在社会化服务体系建设方面,英国建立了从政府服务机构、社会中介服务机构到高校创新服务机构在内的联系紧密的服务体系,而中国相关的社会化服务体系尚未真正建立。 | 葛峙中 Dilek Demirbas | 2007 | 社会科学辑刊2007，，5： | 4 |
| 3 | Living donor liver hilar variations: surgical approaches and implications显示文摘BACKGROUND: Varied vascular and biliary anatomies are common in the liver. Living donor hepatectomy requires precise recognition of the hilar anatomy. This study was undertaken to study donor vascular and biliary tract variations, surgical approaches and implications in living liver transplant patients. METHODS: Two hundred living donor liver transplantations were performed at our institution between 2004 and 2009. All donors were evaluated by volumetric computerized tomography (CT), CT angiography and magnetic resonance cholangiography in the preoperative period. Intraoperative ultrasonography and cholangiography were carried out. Arterial, portal and biliary anatomies were classified according to the Michels, Cheng and Huang criteria. RESULTS: Classical hepatic arterial anatomy was observed in 129 (64.5%) of the 200 donors. Fifteen percent of the donors had variation in the portal vein. Normal biliary anatomy was found in 126 (63%) donors, and biliary tract variation in 70% of donors with portal vein variations. In recipients with single duct biliary anastomosis, 16 (14.4%) developed biliary leak, and 9 (8.1%) developed biliary stricture; however more than one biliary anastomosis increased recipient biliary complications. Donor vascular variations did not increase recipient vascular complications. Variant anatomy was not associated with an increase in donor morbidity. CONCLUSIONS: Living donor liver transplantation provides information about variant hilar anatomy. The success of the procedure depends on a careful approach to anatomical variations. When the deceased donor supply is inadequate living donor transplantation is a life-saving alternative and is safe for the donor and recipient, even if the donor has variant hilar anatomy. | Onur Yaprak Tolga Demirbas Cihan Duran Murat Dayangac Murat Akyildiz Yaman Tokat Yildiray Yuzer | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，5： | 2 |
| 4 | A case study report of acute renal failure associated with Nigella sativa in a diabetic patient显示文摘1 Introduction Nigella sativa, known as black seed, has analgesic, anti-inflammatory, antioxidant and anticancer effects [1-3] . It has been shown to reduce the development of kidney failure when given prior to the use of nephrotoxic drugs particularly due to its antioxidant action [4-7] . However, as far as the authors could ascertain, there is no human study in literature showing these effects. Here we present a case of acute renal failure after the use of N. sativa, | Erol Arslan Selim Sayin Seref Demirbas Mustafa akar Nazire Gke Somak Sirzat Yesilkaya Kenan Saglam | 2013 | Journal of Integrative Medicine2013，11，1： | 2 |
| 5 | Progress and recent trends in biofuels 显示文摘 | Demirbas A | 2007 | Progress in Energy and Combustion Science2007，33，： | 1 |
| 6 | Mechanisms of liquefaction and pyrolysis reactions of biomass显示文摘 | DEMIRBAS A | 2000 | Energy Conversion and Management2000，41，6： | 1 |
| 7 | Potential contribution of biomass to the sustainable energy development显示文摘 | DEMIRBAS M F BALAT M BALAT H | 2009 | Energy Conversion and Management2009，50，7： | 1 |
| 8 | Biodiesel production via non-catalytic SCF method and biodiesel fuel characteristics显示文摘 | | 2006 | Energy Conversion and Management2006，47，： | 1 |
| 9 | Adsorption of heavy metal ions from aqueous solutions by activated carbon prepared from apricot stone显示文摘 | KOBYA M DEMIRBAS E SENTURK E | 2005 | B ioresource Technology2005，96，13： | 1 |
| 10 | Potential evolution of Turkish agricultural residues as bio-gas, bio-char and bio-oil sources显示文摘 | DEMIRBAS A PEHLIVAN E ALTUN T | 2006 | International Journal of Hydrogen Energy2006，31，： | 1 |
| 11 | Mechanisms of liquefaction and pyrolysis reactions of biomass 显示文摘 | DEMIRBAS A | 2000 | Energy Convers Manage2000，41，6： | 1 |
| 12 | Biodiesel production from vegetable oils via catalytic and non catalytic supercritical methanol transersterification methods 显示文摘 | DEMIRBAS A | 2005 | Prog Energy Combast Sci2005，31，56： | 1 |
| 13 | Removal of heavy metal ions from aqueous solu-tions via adsorption onto modi?ed lignin from pulping wastes显示文摘 | CELIK A DEMIRBAS A | 2005 | EnergySources2005，27，12： | 1 |
| 14 | Biodiesel fuels from vegetables oils via catalytic and non-catalytic supercritical alcohol transesterifications and other method: A curvey显示文摘 | Demirbas Ayhan | 2003 | Energy and Management2003，44，13： | 1 |
| 15 | Gaseous products from biomass by py rolysis and gasification: Effects of catalyst on hydro gen yield 显示文摘 | Demirbas A | 2002 | Energy Conversion and Management2002，43，7： | 1 |
| 16 | Optimization of electrocoagulation process for the treatment of metal cutting wastewaters with response surface methodology显示文摘 | Kobya M Demirbas E Bayramoglu M | 2011 | Water A ir Soil Pollut2011，215，： | 1 |
| 17 | Effects of temperature and particle size on bio-char yield from pyrolysis of agricultural residues显示文摘 | Ayhan Demirbas | 2004 | Journal of Analytical and Applied Pyrolysis2004，72，： | 1 |
| 18 | Biomass resource facilities and biomass conversion processing for fuels and chemicals 显示文摘 | Demirbas A | 2001 | Energy Conversion and Management2001，42，11： | 1 |
| 19 | Kinetics for low temperature pyrolysis of black liquor显示文摘 | Demirbas A Kueenek M M Erdogan Y | 1992 | Fuel Science & Technology International1992，10，2： | 1 |
| 20 | Physical properties of briquettes from waste paper and wheat straw mixtures 显示文摘 | Demirbas A | 1999 | Energy Conwersion and Management1999，40，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员