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| 1 | Concurrent use of aromatase inhibitors and hypofractionated radiation therapy显示文摘AIM: To retrospectively assess the acute and long-term toxicity using aromatase inhibitors (AI) therapy concurrently with hypofractionated radiotherapy (HFRT) in breast cancer patients. METHODS: From November 1999 to October 2007, 66 patients were treated with breast HFRT and concurrent AI. In 63 patients (95.5%), HFRT delivered a total dose of 32.5 Gy to the whole breast within 5 wk (five fractions, one fraction per week). Other fractionations were chosen in three patients for the patients' personal convenience. A subsequent boost to the tumor bed was delivered in 35 patients (53.0%). Acute toxicities were scored according to the Common Toxicity Criteria for Adverse Events v3. Late toxicity was defined as any toxicity occurring more than 6 mo after completion of HFRT and was scored according to the Late Effects Normal Tissue Task Force-Subjective, Objective, Management and Analytic scale. RESULTS: At the end of the HFRT course, 19 patients (28.8%) had no irradiation-related toxicity. Acute grade 1-2 epithelitis was observed in 46 patients (69.7%). One grade 3 toxicity (1.5%) was observed. With a median follow-up of 34 mo (range: 12-94 mo), 31 patients (47%) had no toxicity, and 35 patients (53%) presented with grade 1-2 fibrosis. No grade 3 or greater delayed toxicity was observed. CONCLUSION: We found that AI was well tolerated when given concurrently with HFRT. All toxicities were mild to moderate, and no treatment disruption was necessary. Further prospective assessment is warranted. | Cyrus Chargari Pablo Castro-Pena Ivan Toledano Marc A Bollet Alexia Savignoni Paul Cottu Fatima Laki Franois Campana Patricia De Cremoux Alain Fourquet Youlia M Kirova | 2012 | World Journal of Radiology2012，4，7： | 2 |
| 2 | Oxaliplatin plus vinorelbine in advanced non-small cell lung cancer:final results of a multicenter phase Ⅱ study显示文摘 | Monnet I de Cremoux H Soulie P | 2002 | Ann Oncol2002，13，1： | 1 |
| 3 | Phase Ⅰ/Ⅱ study of escalating doses of vinorelbine in combination with oxaliplatin in patients with advanced non-small-cell lung cancer 显示文摘 | Monnet I Soulie P de Cremoux H | 2001 | J Clin Oncol2001，19，2： | 1 |
| 4 | Cross sec- tional study of conventional cervical smear, monolayer cy-tology, and human papillomavirus DNA testing for cervical cancer screening显示文摘 | Coste J Cochand-Priollet B de Cremoux P | 2003 | BMJ2003，326，7392： | 1 |
| 5 | Different outcome of invasive cervical cancer associated with high-risk versus intermediate-risk HPV genotype显示文摘 | de Cremoux P de la Rochefordi e re A Savignoni A | 2009 | Int J Cancer2009，124，4： | 1 |
| 6 | Cost-effectiveness of liquid- based cytology with or without hybrid-capture II HPV test compared with conventional Pap smears:a study by the French Society of Clinical Cytology显示文摘 | Cochand-Priollet B Cartier I De Cremoux P | 2005 | Diagn Cytopathol2005，33，5： | 1 |
| 7 | Cost-effectiveness of liquid-based cytology with or without hybrid-capture I1 HPV test compared with conventional pap smears: a study by the french society of clinical cytology 显示文摘 | Cochand-Priollet B Cartier I De Cremoux P | 2005 | Diagn Cytopathol2005，33，5： | 1 |
| 8 | Oxaliplatin Plus Vinorelbine in advanced non-small-cell lung caner:final results of a multicenter phase II study 显示文摘 | Monnet H Cremoux P Souli S | 2002 | Ann Orcol2002，13，1： | 1 |
| 9 | The photo-crys- tallization of amorphous selenium thin films显示文摘 | Clement R Carballes J C De Cremoux B | 1974 | J Non Cryst Sol- ids1974，15，3： | 1 |
| 10 | Estrogen receptor negative and progesterone receptor positive primary breast cancer:Pathological characteristics and clinical outcome显示文摘 | Bernoux A de Cremoux P Laine-Bidron C | 1998 | Breast Cancer Res Treat1998，49，3： | 1 |
| 11 | Distinctive potentiating effects of cisplatin and/or ifosfamide combined with etoposide in human small cell lung carcinoma xenografts显示文摘 | Nemati F Livartowski A De Cremoux P | 2000 | Clinical Cancer Research2000，6，5： | 1 |
| 12 | Efficiency of the hybrid capture 2 HPV DNA test in cervical cancer screening: A study by the French Society of Clinical Cytology显示文摘 | De Cremoux P Coste J Sastre G X | 2003 | Am J Clin Pathol2003，120，4： | 1 |
| 13 | Phase I /II study of escalating doses of vinorelbine in combination with oxaliplatin in patients with advanced non-small-cell lung cancer显示文摘 | Monnet I Soulié P de Cremoux H | | 0，，： | 1 |
| 14 | Cross sectional study of conventional cervical smear, monolayer cytology, and human papillomavirus DNA testing for cervical cancer screening 显示文摘 | Coste J Cochand-Priollet B de Cremoux P | 2003 | BMJ2003，326，7392： | 1 |
| 15 | Cross sectional study of conventional cervical smear,monolayer cytology,and human papil lomavirus DNA testing for cervical cancer screening显示文摘 | Priollet J De Cremoux P Le Vcecile VLC | 2003 | British Medical Journal2003，4，： | 1 |
| 16 | Different outcome of invasive cervical cancer assoc iatedwith high-risk versus intermediate-risk HPV genotype 显示文摘 | de Cremoux P de la Roehefordiere A Savignoni k | 2009 | Int J Cancer2009，124，4： | 1 |
| 17 | Different outcome of invasive cervical cancer associated with high-risk versus intermediate-risk HPV genotype 显示文摘 | de Cremoux P de la Rochefordiere A Savignoni A | 2009 | Int J Cancer2009，124，4： | 1 |
| 18 | Costeffectiveness of liquid-based cytology with or without hybrid-capture Ⅱ HPV test compared with conventional pap smears : A study by the French Society of Clinical Cytology显示文摘 | Cochand-Priollet B Cartier I de Cremoux P | 2005 | Diagn Cytopathol2005，33，5： | 1 |
| 19 | No evidence ofhuman papillomavirus DNA sequences in invasive breastcarcinoma显示文摘 | de Cremoux P Thioux M Lebigot I | 2008 | Breast Cancer Res Treat2008，109，1： | 1 |
| 20 | Oxaliplatin plus vinorelbine in advanced non-small-cell lung cancer: final results of a multicenter phase Ⅱ study显示文摘 | Monnet H Cremoux P Souli S | 2002 | Ann Oncol2002，13，1： | 1 |
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