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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 2 | Predictive control in power electronics and drives显示文摘 | Cortes P Kazmierkowski M P Kennel R M | 2008 | IEEE Transactions on Industrial Electronics2008，55，12： | 1 |
| 3 | Suitability of SRM and CN glasses as neutron fluence monitors in FT dating显示文摘 | Bellemans F De Corte F Van den Haute P | 1993 | Nuclear Tracks and Radiation Measurements1993，21，4： | 1 |
| 4 | Predictive control of a three-phase neutral-point-clamped inverter显示文摘 | Vargas R Cortes P Ammarm U | 2007 | IEEE Transactions on Industrial Electronics2007，54，5： | 1 |
| 5 | Long - term follow - up of pa- tients with hypereosinophilic syndrome treated with Alemtuzum- ab,an anti- CD52 antibody 显示文摘 | Strati P Cortes J Faded S | 2013 | Clinical lymphoma Myeloma Leuke2013，13，3： | 1 |
| 6 | Identification and proteolytic processing of procardosin A显示文摘 | Ramalho-Santos M Verissimo P Cortes L | 1998 | Eur J Biochem1998，255，1： | 1 |
| 7 | Shallow tunnels in cohesionless soil:Stability of tunnel face显示文摘 | CHAMBON P CORTE J F | 1994 | Journal of Geotechnical Engineering1994，120，7： | 1 |
| 8 | The role retinoid defi- ciency and estrogens as cofactors in cervical cancer显示文摘 | GARIGLIO P GUTIERREZ J CORTES E | 2009 | Arch Med Res2009，40，6： | 1 |
| 9 | The recombination signal sequence -binding protein RBP- 2N functions as a transcriptional repressor 显示文摘 | Dou S Zeng X Cortes P | 1994 | Mol Cell Biol1994，14，5： | 1 |
| 10 | control of a three-phase neutral-point- inverter 显示文摘 | VARGAS Predictive clamped Electronic R CORTES P AMMANN U | 2007 | IEEE Trans on Industrial s2007，54，5： | 1 |
| 11 | Improvements to the Analysis of Floorbeams with Additional Web Cutouts for Orthotropic Plated Decks with Closed Continuous Ribs 显示文摘 | De Corte W Van Bogaert P | 2007 | Steel and Composite Structures2007，7，3： | 1 |
| 12 | Predictive control of a three-phase neutral point clamped inverter显示文摘 | RODRIGUEZ J PONTT J CORTES P | | 0，，05： | 1 |
| 13 | Model predictive control of multilevel cascaded H-bridge inverters显示文摘 | Cortes P Wilson A Kouro S | 2010 | IEEE Transactions on Industrial Electronics2010，57，8： | 1 |
| 14 | Com-parison of idarubicin+ara-C,fludarabine+ara-C,andtopotecan+ara-C-based regimens in treatment ofnewly diagnosed acute myeloid leukemia,refractory a-nemia with excess blasts in transformation,or refrac-tory anemia with excess blasts显示文摘 | ESTEY E H THALL P F CORTES J E | 2001 | Blood2001，98，： | 1 |
| 15 | The effects of imatinib on pregnancy outcome显示文摘 | Pye SM Cortes J Ault P | 2008 | Blood2008，111，： | 1 |
| 16 | Predictive torque control of induction machines based on statespace model显示文摘 | MIRANDA H CORTES P YUz J I | | 0，，06： | 1 |
| 17 | Reproductive cycle of Manila clam Ruditapes philippinarum (Adams and Reeve 1850) ,in Ria of Vigo ( NW Spain ) 显示文摘 | Rodriguez M E Pazo J P Cortes F F | 1992 | Scientian Marina1992，56，1： | 1 |
| 18 | Chronic myeloid leukemia:overview of new agents and comparative analysis显示文摘 | Jain P Kantarjian H Cortes J | 2013 | Curr Treat Options Oncol2013，14，2： | 1 |
| 19 | Amputation and adriamycin in primary osteosarcoma显示文摘 | Cortes E P Holland J F Wang J J | 1974 | N Engl J Med1974，291，19： | 1 |
| 20 | Fracture properties of a fibermetal laminates based on magnesium alloy显示文摘 | W J CANTWELL | 2004 | Journal of Materials Science2004，39，： | 1 |
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