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| 1 | 颅内出血患者抗栓药逆转指南美国神经重症监护学会和美国重症医学会对医疗卫生专业人员的声明显示文摘背景抗栓药的使用,包括抗凝药、抗血小板药和溶栓药,在过去10年中日益增多并且预计将继续上升。虽然抗栓药相关性颅内出血可能是灾难性的,但快速逆转凝血功能障碍可能有助于限制血肿增大和改善转归。方法美国神经重症监护学会联合美国重症医学会组建了一个国际性多机构委员会,涉及的专业领域包括神经重症监护、神经内科、神经外科、卒中、血液学、血液病理学、急诊医学、药学、护理和指南制定,目的是进行文献评价并制定一份循证实践指南。该委员会进行了正式的文献检索,并对符合标准的研究进行了评价。结果利用GRADE方法学,委员会提出了在颅内出血情况下逆转维生素K拮抗药、直接Xa因子拮抗药、直接凝血酶抑制药、普通肝素、低分子肝素、类肝素、戊多糖、溶栓药和抗血小板药的推荐意见。结论该指南提供了及时和循证的抗栓药逆转策略以协助临床医生治疗抗栓药相关性颅内出血。 | Jennifer A. Frontera John J. Lewin Ⅲ Alejandro A. Rabinstein Imo P. Aisiku Anne W. Alexandrov Aaron M. Cook Gregory J. del Zoppo Monisha A. Kumar Ellinor I. B. Peerschke Michael F. Stiefel Jeanne S Teitelbaum Katja E. Wartenberg Cindy L. Zerfoss 杨一萍 谢丽丽 宁小金 季宇腾 柯开富 | 2016 | 国际脑血管病杂志2016，24，11： | 24 |
| 2 | A20 is dynamically regulated in the heart and inhibits the hypertrophic response显示文摘 | Cook S A Novikov M S Ahn Y | 2003 | Circulation2003，108，6： | 8 |
| 3 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 4 | 显示文摘 | Jahan M S Cooke D W Hults W L | 1990 | J Luminesc1990，47，： | 2 |
| 5 | 相对于男性,女性进行冠状动脉造影产生的额外的心血管病风险与严重受损的冠状动脉血流储备,而非阻塞性疾病相关显示文摘与男性相比,女性的心血管病死亡率更高,但是阻塞性冠状动脉疾病(coronary artery disease,CAD)在女性中不太普遍。冠状动脉血流储备(coronary flow reserve,CFR)是大、小血管CAD和心肌缺血的综合测量指标,可识别出具有心血管病死亡风险的患者,但其在临床实践中不是常规测量的指标。该研究试图调查性别、CFR和血管造影CAD严重程度对不良心血管事件的影响。 | 刘莉 叶鹏 Taqueti VR Shaw LJ Cook NR Murthy VL Shah NR Foster CR Hainer J Blankstein R Dorbala S Di Carli MF | 2016 | 中华高血压杂志2016，24，11： | 2 |
| 6 | 99Tcmlabeled HL91 to identify tumor hypoxia:correlation with fluorine-18 FDG显示文摘 | Cook GJ Houston S Barrington SF | 1998 | J Nucl Med1998，39，1： | 2 |
| 7 | Application of times-series analysis techniques for freeway incldent显示文摘 | Ahmed S A Cook A R | 1989 | Transportation Research1989，，2： | 1 |
| 8 | Evidence-based clinical practice guideline for the prevention of ventilator-associated pneumonia显示文摘 | Dodek P Keenan S Cook D | 2004 | Ann Intern Med2004，141，4： | 1 |
| 9 | Short term evaluation of carbon coated and uncoated porous titanium implants clin显示文摘 | COOK S D HADDAD R J | 1989 | Clin Mater1989，4，： | 1 |
| 10 | Thyroid hormone regulates earnitine pahnitoyl transferase I a gene expression through elements in the promoter and first intron 显示文摘 | Jansen M S Cook G A Song S L | 2000 | J Biol Chem2000，275，34： | 1 |
| 11 | Assessment of management alternatives on a small agricultural watershed 显示文摘 | Mostaghimi S Park S W Cooke R A | 1997 | Water Research1997，31，8： | 1 |
| 12 | Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity 显示文摘 | Wang Z Cook T Alber S | 2004 | Cancer Res2004，64，4： | 1 |
| 13 | A study of 4-substituted 5,5-diaryl oxazolidin-2-ones as efficacious chiral auxiliaries显示文摘 | Gibson C L Gillon K Cook S | 1998 | Tetrahedron Lett1998，39，： | 1 |
| 14 | Internal migration and health in China 显示文摘 | Hu X Cook S Salazar M A | 2008 | The Lancet2008，372，9651： | 1 |
| 15 | Nitric oxide regula- tion of gonadotrophin seeretion in prepubertal heifers显示文摘 | Honaramooz A Cook S J Beard A P et ol | 1999 | J Neu- roendoerinol1999，11，9： | 1 |
| 16 | Analysis of compressive fracture in rock using statistical techniques : Part II : effect of mi- croscale heterogeneity on macroscopic deformation 显示文摘 | Blair S C Cook N G | 1998 | International Journal of Rock Mechanics and Mining Sciences 8< Geomechanics Abstracts1998，35，7： | 1 |
| 17 | Analysis of freeway traffic time- series data by using Box-Jenkins technique 显示文摘 | Ahmaed M S Cook A R | 1979 | Trans- portation Research Board1979，，722： | 1 |
| 18 | Telephone nursecounseling for medication adherence in ulcerative colitis : apreliminary study 显示文摘 | Cook PF Emiliozzi S El-Hajj D | 2010 | Patient Educ Couns2010，81，2： | 1 |
| 19 | Consonant identification in N-talker babble is a nonmonotonic function of N(L)显示文摘 | Simpson S Cooke M | | 0，，05： | 1 |
| 20 | Recognizing speech under a processing load:Dissociatting energetic from informational factors显示文摘 | Mattys S L Brooks J Cooke M | | 0，，03： | 1 |
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