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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 高羊茅干草部分替代玉米和紫花苜蓿青贮饲料对奶牛消化、泌乳性能的影响显示文摘试验旨在研究高羊茅干草替代玉米或紫花苜蓿青贮对奶牛中性洗涤纤维(NDF)消化率、泌乳性能的影响。选取初产哺乳荷斯坦奶牛(产奶75±35 d)24头,经产荷斯坦奶牛(产奶68±19 d)40头,随机分成4组,共设置32个进料闸门,记录采食量。每组8个进料阀门,以1头牛为1个试验单位,每头牛试验过程中可接触8个进料闸门。试验用高羊茅干草(TF)取代玉米青贮饲料(CS)或紫花苜蓿青贮饲料(AS),试验设计为:33%AS和67%CS(空白组)、60%TF和40%AS(试验1组)、60%TF和40%CS(试验2组)、33%TF和67%CS(试验3组)。试验进行7周,前2周进行预饲。试验结果表明,各组间牛奶产量无显著差异,平均值为40.4 kg·d^(-1)。各组间牛奶中脂肪含量和浓度、蛋白质含量和浓度均无显著差异,平均值为1.58 kg·d^(-1)和3.94%、1.28 kg·d^(-1)和3.15%。与试验1组(22.1 kg·d^(-1))、试验3组(22.7 kg·d^(-1))相比,空白组的干物质摄入量最高,为24.5kg·d^(-1)。各组间总的干物质消化率无显著差异,平均值为66.2%。与试验2组(44.4%)、试验3组(45.3%)相比,空白组的NDF消化率较低,为37.8%,与试验1组(42.4%)相近。各组间奶牛体内NDF消化率(42.3%)与预估的NDF消化率(42.6%)相近。试验结果表明,饲喂高羊茅干草可提高饲料中NDF消化率,部分替代玉米和紫花苜蓿时对产奶量无显著影响,在市场价格较低时,可作为经济实用的奶牛饲料。 | Bender R W Lopes F Cook D E Combs D K | 2016 | 饲料博览2016，0，8： | 2 |
| 3 | Assessment of management alternatives on a small agricultural watershed 显示文摘 | Mostaghimi S Park S W Cooke R A | 1997 | Water Research1997，31，8： | 1 |
| 4 | Fracture characteristics of three metals subjected to carious strains, strains rates, temper- atures and pressures 显示文摘 | Johnson G R Cook W H | 1985 | Eng Fract Mech1985，21，1： | 1 |
| 5 | Effects of T-2 mycotoxin on gastrointestinal tissues : a review of in vivo and in vitro models 显示文摘 | WORRELL N R MALLETT A K COOK W M | 1989 | Environ Toxicol1989，18，1： | 1 |
| 6 | Jacked piles in London Clay:a study of load transfer and settlement under working conditions 显示文摘 | Cooke R W Price G Tarr K | 1979 | Geotechnique1979，29，2： | 1 |
| 7 | Construction and testing of micmsatellite database containing more than 500 tomoto varieties 显示文摘 | BREDEMEIJER G M M COOK R J GANAL M W | 2002 | Theor Appl Genet2002，105，： | 1 |
| 8 | Fiber Optic Lever Displacement Transducer显示文摘 | Cook R O Hamm C W | 1979 | Applied Optics1979，18，19： | 1 |
| 9 | A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus显示文摘 | BAYLISS C D PETERS R W COOK J K A | 1991 | Arch Virol1991，120，： | 1 |
| 10 | The deuterium to hydrogen ratios of sap in trees: implications for water sources and tree ring deuterium to hydrogen ratios显示文摘 | White J W C Cook E R Lawrence J R | 1985 | Geochimica Et Cosmochimiea Aeta1985，49，： | 1 |
| 11 | Assessment of the uniformity of wheat and tomato varieties at DNA microsatel- lite loci 显示文摘 | Cooke R J Bredemeijer G M M Ganal M W el al | 2003 | 132 : 33 ! -3412003，132，： | 1 |
| 12 | Using groundwater levels to esti- mate recharge显示文摘 | Healy R W Cook P G | 2002 | Hydrogeology Journal2002，10，1： | 1 |
| 13 | Toxic equivalency factors of polychlorinated dibenzo-p-dioxin, dibenzofuran and biphenyl congeners based on early life stage mortality in rainbow trout ( Oncorhynchus mykiss) 显示文摘 | Zabel E W Cook P M Peterson R E | 1995 | Aquatic Toxicology1995，31，： | 1 |
| 14 | A model for case assessment and interpretation显示文摘 | Cook R Evett W Jackson G | 1998 | Science and Justice1998，38，： | 1 |
| 15 | Choosing appropriate techniques for quantifying groundwater recharge显示文摘 | SCANLON B R HEALY R W COOK P G | 2002 | Hydrogeology Journal2002，，10： | 1 |
| 16 | Curly bare (cub) ,a new mouse mutation on chromosome 11 cau- sing skin and hair abnormalities, and a modifies gene( mcub) on chromosome 5 显示文摘 | Johnson K R Lane P W Cook S A | 2003 | Genomics2003，81，1： | 1 |
| 17 | Endoscopic partial inferior turbinoplasty显示文摘 | DELDEN M R COOK P R DAVIS W E | 1999 | Otolaryngol Head Neck Surg1999，121，： | 1 |
| 18 | Fracture characteristics of three metals subjected to various strains, strains rates, temperatures and pressures显示文摘 | Johnson G R Cook W H | 1985 | Engineering Fracture Mechanics1985，21，1： | 1 |
| 19 | A hierarchy of propositions: deciding which level to address in casework显示文摘 | Cook R Evett W Jackson G | 1998 | Science & Justice1998，38，： | 1 |
| 20 | Second-Generation RISC Floating Point with Multiply-Add Fused显示文摘 | E Hokenek R K Montoye P W Cook | 1990 | IEEE Journal of Solid-State Circuits1990，25，5： | 1 |
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