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| 1 | Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis显示文摘BACKGROUND Rotator cuff pathology is a very common source of shoulder pain.Similarly,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar symptoms.Surgical management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RCR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RCR in the setting of GHOA.AIM To evaluate if a relationship exists between outcomes of RCR in the setting of GHOA.METHODS This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between 2010-2017.Patients were stratified based on rotator cuff tear size and glenohumeral osteoarthritis severity.Cohorts were paired 1:1 with patients without glenohumeral osteoarthritis.Patients included had a minimum two year follow-up.Rate of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were collected.RESULTS A total of 142 patients were included.The number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without GHOA.Following rotator cuff repair,both groups showed favorable patientreported outcomes.CONCLUSION Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis. | Ian S Hong Allison J Rao Tyler L CarlLee Joshua D Meade Daniel J Hurwit Gregory Scarola David P Trofa Shadley C Schiffern Nady Hamid Patrick M Connor James E Fleischli Bryan Michael Saltzman | 2022 | World Journal of Orthopedics2022，13，7： | 2 |
| 2 | Personalising pancreas cancer treatment:When tissue is the issue显示文摘The treatment of advanced pancreatic cancer has not moved much beyond single agent gemcitabine until recently when protocols such as FOLFIRINOX(fluorouracil,leucovorin,irinotecan and oxaliplatin)and nab-paclitaxelgemcitabine have demonstrated some improved outcomes.Advances in technology especially in massively parallel genome sequencing has progressed our understanding of the biology of pancreatic cancer especially the candidate signalling pathways that are involved in tumourogenesis and disease course.This has allowed identification of potentially actionable mutations that may be targeted by new biological agents.The heterogeneity of pancreatic cancer makes tumour tissue collection important with the aim of being able to personalise therapies for the individual as opposed to a one size fits all approach to treatment of the condition.This paper reviews the developments in this area of translational research and the ongoing clinical studies that will attempt to move this into the everyday oncology practice. | Katrin M Sjoquist Venessa T Chin Lorraine A Chantrill Chelsie O'Connor Chris Hemmings David K Chang Angela Chou Marina Pajic Amber L Johns Adnan M Nagrial Andrew V Biankin Desmond Yip | 2014 | World Journal of Gastroenterology2014，20，24： | 2 |
| 3 | : Identification of cytogenetic subgroups and karyotypic pathways of clonal evolution in follicular lymphomas 显示文摘 | Hoglund M Sehn L Connors JM | 2004 | Genes Chromosomes Cancer2004，39，： | 1 |
| 4 | A novel Gastrokine,Gkn3,marks gastric atrophy and shows evidence of adaptive gene loss in humans显示文摘 | Menheniott TR Peterson AJ O'Connor L | 2010 | Gastroenterology2010，138，5： | 1 |
| 5 | Heavy metal sequential extraction methods-A modification for tropical soils显示文摘 | SILVEIRA M L ALLEONI L R F O' CONNOR G A | 2006 | Chemosphere2006，64，： | 1 |
| 6 | Effects of residual and reapplied biosolids on performance and mineral status of grazing beef steers显示文摘 | Tiffany M E Me Dowell L R O'connor G A etal | 2002 | Journal of Animal Science2002，80，： | 1 |
| 7 | The cytosolic subunit p67^phax contains an NADPH-binding site that participates in catalysis by the leukocyte NADPH oxidase 显示文摘 | SMITH R M CONNOR J A CHEN L M | 1996 | J Clin Invest1996，，98： | 1 |
| 8 | Enteric coated HPMC capsules designed to achieve intestinal targeting显示文摘 | Ewart T Cole Robert A Scott Alyson L Connor Ian R Wilding Hans-U Petereit Carsten Schminke Thomas Beckert Dominique Cadé | 2002 | International Journal of Pharmaceutics2002，，1： | 1 |
| 9 | A histochemical study of iron,transferrin,and ferritin in Alzheimer’s diseased brains显示文摘 | Connor J R Menzies S L St Martin S M | 1992 | J Neurosci Res1992，31，1： | 1 |
| 10 | Opportunities for im- proving milk production efficiency in dairy cattle: triennial lactation symposium 显示文摘 | Connor E E Hutchison J L Olson K M | 2011 | J Anim Sci2011，90，： | 1 |
| 11 | A standardized definition of ischemic cardiomyopathy for use in clinical research显示文摘 | Felker G M Shaw L K O'Connor C M | 2002 | J Am Coil Cardiol2002，39，2： | 1 |
| 12 | Evaluation of performance characteristics of the medicinal leech(hirudo medicinalis) for the treatment of venous congestion显示文摘 | CONNOR N P HEISEY D M | 2002 | Plast Reconstr Surg2002，109，1： | 1 |
| 13 | The chromogranin secretogranin family显示文摘 | Taupenot L Harper KL O'Connor DT | 2003 | N Engl J Med2003，348，12： | 1 |
| 14 | Intra-organizational networking for innovation-based corporate entrepreneur- ship 显示文摘 | Kelley D Peters L O'Connor G C | 2009 | Journal of Business Venturing2009，24，3： | 1 |
| 15 | Mantle cell lymphoma: a clinicopathologic study of 80 cases 显示文摘 | Argatoff L H Connors J M Klasa R J | 1997 | Blood1997，89，6： | 1 |
| 16 | Apoptosis signaling显示文摘 | Strasser A O'Connor L Dixit V M | 2000 | Annu Rev Biochem2000，69，1： | 1 |
| 17 | Vasopressin: a new target for the treatment of heart failure显示文摘 | Craig R Lee Michael L Watkins J.Herbert Patterson Wendy Gattis Christopher M O'Connor Mihai Gheorghiade Kirkwood F Adams | 2003 | American Heart Journal2003，，1： | 1 |
| 18 | The acromio- humeral and eoraeohumeral intervals are abnormal in rotator cuff tears with muscle fatty degeneration 显示文摘 | Nove-Josserand L Edwards TB O'Connor DP | 2005 | Clin Orthop Relat Res2005，，433： | 1 |
| 19 | Recent Advances in the Liquid-Phase Syntheses of Inorganic Nanoparticles显示文摘 | CUSHING B L KOLESNICHENKO V L O'CONNOR C J | 2004 | Chem Rev2004，104，： | 1 |
| 20 | Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders 显示文摘 | Presta L G Chen H Connor S J | 1997 | Cancer Res1997，57，20： | 1 |
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