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| 1 | Prognostic factors and time-related changes influence results of colorectal liver metastases surgical treatment:A single-center analysis显示文摘AIM:To analyze the prognostic factors involved in survival and cancer recurrence in patients undergoing surgical treatment for colorectal liver metastases(CLM) and to describe the effects of time-related changes on survival and recurrence in these patients.METHODS:From January 1994 to January 2006,236 patients with CLM underwent surgery with the aim of performing curative resection of neoplastic disease at our institution and 189(80%) of these patients underwent resection of CLM with curative intention.Preoperative,intraoperative and postoperative data,including primary tumor and CLM pathology results,were retrospectively reviewed.Patients were divided into two time periods:a first period from January 1994 to January 2000(n = 93),and a second period from February 2000 to January 2006(n = 143).RESULTS:Global survival at 1,3 and 5 years in patients undergoing hepatic resection was 91%,54% and 47%,respectively.Patients with preoperative extrahepatic disease,carcinoembryonic antigen(CEA) levels over 20 ng/dL,more than four nodules or extrahepatic invasion at pathological analysis had worse survival.Tumor recurrence rate at 1 year was 48.3%,being more frequent in patients with preoperative and pathological extrahepatic disease and CEA levels over 20 ng/dL.Although patients in the second time period had more adverse prognostic factors,no differences in overall survival and recurrence were observed between the two periods.CONCLUSION:Despite advances in surgical technique and better adjuvant treatments and preoperative imaging,careful patient staging and selection is crucial to continue offering a chance of cure to patients with CLM. | Josep Martí María Marta Modolo Josep Fuster Jaume Comas Rebeca Cosa Joana Ferrer Victor Molina Juan Romero Constantino Fondevila Ramón Charco Juan Carlos García-Valdecasas | 2009 | World Journal of Gastroenterology2009,15,21: | 9 |
| 2 | Radiation and concomitant chemotherapy for patients with glioblastoma multiforme显示文摘Postoperative external beam radiotherapy was considered the standard adjuvant treatment for patients with glioblastoma multiforme until the advent of using the drug temozolomide(TMZ) in addition to radiotherapy. High-dose volume should be focal, minimizing whole brain irradiation. Modern imaging, using several magnetic resonance sequences, has improved the planning target volume definition. The total dose delivered should be in the range of 60 Gy in fraction sizes of 1.8-2.0 Gy. Currently, TMZ concomitant and adjuvant to radiotherapy has become the standard of care for glioblastoma multiforme patients. Radiotherapy dose-intensification and radiosensitizer approaches have not improved the outcome. In spite of the lack of high quality evidence, stereotactic radiotherapy can be considered for a selected group of patients. For elderly patients, data suggest that the same survival benefit can be achieved with similar morbidity using a shorter course of radiotherapy(hypofractionation). Elderly patients with tumors that exhibit methylation of the O-6-methylguanine-DNA methyltransferase promoter can benefit from TMZ alone. | Salvador Villà Carme Balaà Sílvia Comas | 2014 | Chinese Journal of Cancer2014,33,1: | 6 |
| 3 | Time lag characteristics of sap flow in seed-maize and their implications for modeling transpiration in an arid region of Northwest China显示文摘Plant capacity for water storage leads to time lags between basal stem sap flow and transpiration in various woody plants. Internal water storage depends on the sizes of woody plants. However, the changes and its influencing factors in time lags of basal stem flow during the development of herbaceous plants including crops remain unclear. A field experiment was conducted in an arid region of Northwest China to examine the time lag characteristics of sap flow in seed-maize and to calibrate the transpiration modeling. Cross-correlation analysis was used to estimate the time lags between stem sap flow and meteorological driving factors including solar radiation(R_s) and vapor pressure deficit of the air(VPD_(air)). Results indicate that the changes in seed-maize stem sap flow consistently lagged behind the changes in R_s and preceded the changes in VPD_(air) both on hourly and daily scales, suggesting that light-mediated stomatal closures drove sap flow responses. The time lag in the maize's sap flow differed significantly during different growth stages and the difference was potentially due to developmental changes in capacitance tissue and/or xylem during ontogenesis. The time lags between stem sap flow and R_s in both female plants and male plants corresponded to plant use of stored water and were independent of total plant water use. Time lags of sap flow were always longer in male plants than in female plants. Theoretically, dry soil may decrease the speed by which sap flow adjusts ahead of shifts in VPD_(air) in comparison with wet soil and also increase the speed by which sap flow adjusts to R_s. However, sap flow lags that were associated with R_s before irrigation and after irrigation in female plants did not shift. Time series analysis method provided better results for simulating seed-maize sap flow with advantages of allowing for fewer variables to be included. This approach would be helpful in improving the accuracy of estimation for canopy transpiration and conductance using meteorological measurements. | BO Xiaodong DU Taisheng DING Risheng Louise COMAS | 2017 | Journal of Arid Land2017,9,4: | 4 |
| 4 | Use of Dobutamine stress echocardiography in diagnosing coronary artery disease显示文摘 | COMA C ARI M | 1986 | Circulation1986,73,2: | 2 |
| 5 | Edible anti- microbial films based on chitosan matrix 显示文摘 | Coma V Martial-Gros A Garreau S | 2002 | Journal of Food Science2002,67,3: | 1 |
| 6 | Chem Rev 显示文摘 | Avelino Coma | 1997 | 97(6): 2373-24201997,,: | 1 |
| 7 | Creaming stability of oil in water (O/W) emulsions: Influence of pH on soybean protein-lecithin interaction显示文摘 | Comas DI Wagner JR Tom:s MC | 2006 | FoodHydrocol2006,20,7: | 1 |
| 8 | Adding a statin to a combina- tion of ACE inhibitor and ARB normalizes proteinuria in experi- mental diabetes, which translates into full renoprotection 显示文摘 | Zoja C Coma D Gagliardini E | 2010 | Am J Physiol Renal Physiol2010,299,5: | 1 |
| 9 | Effects of MCP-1 inhibition by bindarit therapy in a rat model of polycystic kidney disease显示文摘 | Zoja C Coma D Locatelli M | 2015 | Nephron2015,129,1: | 1 |
| 10 | Multiple risk factors in root survivorship:a 4-year study in concord grape显示文摘 | Anderson L J Comas L H Lakso A N | 2003 | New Phytologist2003,158,3: | 1 |
| 11 | Cyclone pressure drop and efficiency with and without an inlet vane显示文摘 | M Comas J Comas C Chetrit J Casal | 1991 | Powder Technology1991,66,: | 1 |
| 12 | Overexpression of FABP 7 in Down Syndrome Fetal Brain Is Associated with PKNOX1 Gene-dosage Imbalance 显示文摘 | Sanchez Font M F Bosch Comas A Marfany G | 2003 | Nuclei Acids Res2003,31,11: | 1 |
| 13 | Routine use of the Pneumonia Severity Index for guiding the site-of-treatment decision of patients with pneumonia in the emergency department:a muhicenter,prospective,observational, controlled cohort study 显示文摘 | Renaud B Coma E Labarere J | 2007 | Clin Infect Dis2007,44,1: | 1 |
| 14 | One-step reverse transcription polymerase chain reaction for semiquantitative analysis of mRNA expression显示文摘 | Fuster G Vicente R Coma M | 2002 | Methods Find Exp Clin Pharmaco12002,24,5: | 1 |
| 15 | Effects of ultraviolet light(315nm),temperature and relative humidity on the degradation of polylactic acid plastic films显示文摘 | Alain Copinet Celine Bertrand Stephanie Govindin Veronique Coma Yves Couturier | 2004 | Chemosphere2004,55,: | 1 |
| 16 | Abnormal first-trimester ductus venosus blood flow:a marker of cardiac defects in fetuses with normal karyotype and nuchal translucency显示文摘 | Martinez JM Comas M Borrell A | 2010 | Ultrasound Obstet Gynecol2010,35,3: | 1 |
| 17 | 饲养与肉质显示文摘营养对肉质的某些方面可产生显著影响 ,同时我们也不能忘记肉质与其它因素之间的关系 ,比如与遗传的关系。 | 梁文雁 刘逸 Jaume Coma | 2001 | 国外畜牧学(猪与禽)2001,,3: | 1 |
| 18 | Designing and building real environmental decision support systems显示文摘 | Poch M Comas J Rodriguez-Roda I | 2004 | Environmental Modelling & Software2004,19,: | 1 |
| 19 | Use of plasma urea nitrogen as a rapid response criterion to determine the lysine requirement of pigs 显示文摘 | Coma J Carrion D Zimmerman D R | 1995 | Journal of Animal Science1995,73,2: | 1 |
| 20 | Use of siRNAs and antisense oligonucleotides against survivin RNA to inhibit steps leading to tumorangiogenesis显示文摘 | Noe V Lavarino C | 2004 | Oligonucleotides2004,14,2: | 1 |