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| 1 | New eolian red clay sequence on the western Chinese Loess Plateau linked to onset of Asian desertification about 25 Ma ago显示文摘The expansion of inland Asia deserts has considerably influenced the environmental, social and economic activities in Asia. Aridification of inland Asia, especially timing of the initiation of Asian desertification, is a contentious topic in paleoclimatology. Late Cenozoic eolian loess-red clay sequences on the Chinese Loess Plateau, which possess abundant paleoclimatic and paleo-environmental information, can be regarded as an indicator of inland Asia desertification. Here we present a detailed magnetostratigraphic investigation of a new red clay sequence about 654 m in Zhuanglang located at the western Chinese Loess Plateau. Sedimentological, geochemical, mineralogical, and quartz morphological lines of evidence show that the red clay is of eolian origin. Magnetostratigraphic correlations indicate that this core sequence spans from 25.6 to 4.8 Ma, and typical eolian red clay appears as early as 25 Ma. This extends the lower limit of the red clay on the Chinese Loess Plateau from the previously thought early Miocene back into the late Oligocene. This new red clay record further implies that the inland Asia desertification was initiated at least by the late Oligocene. This sequence provides a unique high-resolution geological record for understanding the inland Asia desertification process since the late Oligocene. | QIANG XiaoKe AN ZhiSheng SONG YouGui CHANG Hong SUN YouBin LIU WeiGuo AO Hong DONG JiBao FU ChaoFeng WU Feng LU FengYan CAI YanJun ZHOU WeiJian CAO JunJi XU XinWen AI Li | 2011 | Science China Earth Sciences2011，54，1： | 73 |
| 2 | Mesozoic subduction-accretion zone in northeastern South China Sea inferred from geophysical interpretations显示文摘A segment of Mesozoic subduction-accretion zone was inferred across the northeastern South China Sea at approximately NE45° orientation. Basic evidence includes the following: A belt of peek gross horizontal Bouguer gravity gradient (PGHGBA) is comparable in size and intensity to that of the Manila subduction-accretion zone. A belt of high positive magnetic anomalies appears to the north and sub-parallel to the PGHGBA, representing the volcanic arc associated to the subduction zone. The PGHGBA crosses obliquely both Cenozoic structures and present seafloor topography, indicating a pre-Cenozoic age. The segment is offset left-laterally by NW-running strike-slip faults, in concord with the Mesozoic stress field of South China. In addition, the existence of the subduction zone is supported by wide-angle seismic data obtained in different years by different institutions. At approximate localities, a north-dipping ramp of Moho surface is indicated by records of ocean-bottom seismometers, and a strong reflector about 8 km beneath the Moho reflector is indicated by both OBS and long-cable seismic records. The identification of a segment of Mesozoic subduction zone in NE South China Sea fills nicely the gap of the Great Late Mesozoic Circum SE Asia Subduction-acrretion Zone, which extended from Sumatra, Java, SE Kalimantan to N Palawan, and from Taiwan, Ryukyu to SW Japan. | ZHOU Di1, WANG Wanyin2, WANG Jialin3, PANG Xiong4, CAI Dongsheng5 & SUN Zhen1 1. Key Laboratory of Marginal Sea Geology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guang- zhou 510301, China 2. College of Geological and Topographical Engineering, Chang’an University, Xi’an 710054, China 3. Key Laboratory of Marine Geology, Tongji University, Shanghai 200092, China 4. China National Offshore Oil Co. Limited – Shenzhen Branch, Shenzhen 518067, China 5. China National Offshore Oil Co. Limited – Research Center, Beijing 100027, China | 2006 | Science China Earth Sciences2006，49，5： | 52 |
| 3 | Ultrahigh pressure (>7 GPa) gneissic K-feldspar (-bearing) garnet clinopyroxenite in the Altyn Tagh, NW China: Evi- dence from clinopyroxene exsolution in garnet显示文摘The exsolution of clinopyroxene and rutile in coarse-grain garnet is found in the gneissic K-feldspar(-bearing) garnet clinopyroxenite from Yinggelisayi in the Altyn Tagh, NW China. The maximum content of the exsolved clinopyroxene in the garnet is up to >5% by volume. The reconstructed precursor garnet (Grt1) before exsolution has a maximum Si content of 3.061 per formula uint, being of supersilicic or majoritic garnet. The peak-stage metamorphic pressure of >7 GPa is estimated using the geobarometer for volume percentage of exsolved pyroxene in garnet and the Si-(Al+Cr) geobarometer for majoritic garnet, and the temperature of about 1000℃ using the ternary alkali-feldspar geothermometer and the experimental data of ilmen- ite-magnetite solid solution. The protoliths of the rocks are intra-plate basic and intermediate ig- neous rocks, of which the geochemical features indicate that they are probably the products of the evolution of basic magma deriving from the continental lithosphere mantle. The rocks are in outcrops associated with ultrahigh pressure garnet-bearing lherzolite and ultrahigh pressure garnet granitoid gneiss. All of these data suggest that the ultrahigh pressure metamorphic rocks in the Altyn Tagh are the products of deep-subduction of the continental crust, and such deep- subduction probably reaches to >200 km in depth. This may provide new evidence for further discussion of the dynamic mechanism of the formation and evolvement of the Altyn Tagh and the other collision orogenic belts in western China. | LIU Liang1,3, CHEN Danling1, ZHANG Anda1, SUN Yong1, WANG Yan1, YANG Jiaxi1,2 & LUO Jinhai1 1. Key Laboratory of Continental Dynamics of the Ministry of Education of China, Northwest University, Xi’an 710069, China 2. College of Earth Science and Land Resources, Chang’an University, Xi’an 710054, China 3. The Laboratory of Orogen and Basin of the Ministry of Education, Peking University, Beijing 100871, China | 2005 | Science China Earth Sciences2005，48，7： | 38 |
| 4 | 西安相家巷遗址秦封泥的发掘显示文摘西安相家巷遗址(简称“CH相”)位于西安市未央区六村堡乡相家巷村南的东西向公路以南500米处,其东邻一条南北向的干渠,南靠一条东西向的土路。该遗址地处汉长安城桂宫遗址东北角外侧(图一;图二)。1996年,相家巷村村民在此地挖积肥坑时,发现了大量封泥。 | Han Chang’an City Archaeological Team,IA,CASS | 2001 | 考古学报2001，，4： | 36 |
| 5 | Magnetism parameters characteristics of drilling deposits in Jianghan Plain and indication for forming of the Yangtze River Three Gorges显示文摘The forming time of the Yangtze River Three Gorges is considered as one of keys in the research on the Yangtze River,also is one of the most disputed hotspots.In order to solve the difficult problem,the authors adopt the internationally recognized thoughts and methods of substance tracing from source to sink.The lithologic characteristics,magnetic parameters and magnetic mineral characteristics of deposits in 2 bores are analyzed,which are both sampled from the sedimentary center of the Jianghan Plain.The results are as follows:At about 110 m depth of the core,the contents of coarse materials and stable magnetic mineral both increase significantly.Meanwhile,the magnetic susceptibility of sediment,saturation isothermal remanent magnetization and magnetic susceptibility values of anhysteretic remanent magnetism increase suddenly,which all reflect that at about 110 m depth,the important adjustment has appeared in water system of the Jianghan Plain,and the sedimentary environment and material composition have changed greatly.And it may be the horizon where the Yangtze River Three Gorges formed,its forming time reflected by the paleomagnetic dating is between 1.17 and 1.12Ma B.P. | ZHANG YuFen LI Chang'An WANG QiuLiang CHEN Liang Ma YongFa KANG ChunGuo | 2008 | Chinese Science Bulletin2008，53，4： | 34 |
| 6 | Compound Danshen injection improves endotoxin-induced microcirculatory disturbance in rat mesentery显示文摘AIM: To investigate the effect of compound Danshen injection on lipopolysaccharide (LPS)-induced rat mesenteric microcirculatory dysfunctions and the underlying possible mechanism by an inverted intravital microscope and high-speed video camera system. METHODS: LPS was continuously infused through the jugular artery of male Wistar rats at the dose of 2 mg/kg per hour. Changes in mesenteric microcirculation,such as diameters of arterioles and venules,velocity of RBCs in venules,leukocyte rolling,adhesion and emigration,free radicals released from post-capillary venules,FITC- albumin leakage and mast cell degranulation,were observed through an inverted intravital microscope assisted with CCD camera and SIT camera. Meanwhile,the expression of adhesion molecules CD11b/CD18 and the production of free radical in neutrophils,and the expression of intercellular adhesion molecule 1 (ICAM-1) in human umbilical vein endothelial cells (HUVECs) were quantified by flow cytometry (FACS) in vitro. RESULTS: The continuous infusion with LPS resulted in a number of responses in microcirculation,including a significant increase in the positive region of venulestained with Monastral blue B,rolling and adhesion of leukocytes,production of oxygen radical in venular wall,albumin efflux and enhanced mast cell degranulation in vivo,all of which,except for the leukocyte rolling,were attenuated by the treatment with compound Danshen injection. Experiments performed in vitro further revealed that the expression of CD11b/CD18 and the production of oxygen free radical in neutrophils,and the expression of ICAM-1 in HUVECs were increased by exposure to LPS,and they were attenuated by compound Danshen injection. CONCLUSION: These results suggest that compound Danshen injection is an efficient drug with multi-targeting potential for improving the microcirculatory disturbance. | Jing-Yan Han Yoshinori Horie Soichiro Miura, Yasutada Akiba Jun Guo Dan Li Jing-Yu Fan Yu-Ying Liu Bai-He Hu Li-Hua An Xin Chang Man Xu De-An Guo Kai Sun Ji-Ying Yang Shu-Ping Fang Ming-Ji Xian Masahiro Kizaki Hiroshi Nagata Toshifumi Hibi | 2007 | World Journal of Gastroenterology2007，13，26： | 26 |
| 7 | Treatment strategies using adefovir dipivoxil for individuals with lamivudine-resistant chronic hepatitis B显示文摘AIM:To investigate retrospectively the long-term efficacy of various treatment strategies using adefovir dipivoxil(adefovir) in patients with lamivudine-resistant chronic hepatitis B.METHODS:We included 154 consecutive patients in two treatment groups:the 'add-on' group(n = 79),in which adefovir was added to ongoing lamivudine treatment due to lamivudine resistance,and the 'switch/combination' group(n = 75),in which lamivudine was first switched to adefovir and then re-added later as needed.The 'switch/combination' group was then divided into two subgroups depending on whether participants followed(group A,n = 30) or violated(group B,n = 45) a proposed treatment strategy that determined whether to add lamivudine based on the serum hepatitis B virus(HBV) DNA levels(< 60 IU/mL or not) after 6 mo of treatment(roadmap concept).RESULTS:The cumulative probability of virologic response(HBV DNA < 60 IU/mL) was higher in group A than in the 'add-on' group and in group B(P < 0.001).In contrast,the cumulative probability of virologic breakthrough was lower in the 'add-on' group than in group B(P = 0.002).Furthermore,the risk of virologic breakthrough in the multivariate analysis was significantly lower in the 'add-on' group than in group A(hazard ratio = 0.096;95%CI,0.015-0.629;P = 0.015).CONCLUSION:The selective combination of adefovir with lamivudine based upon early treatment responses increased the odds of virologic breakthrough relative to the use of uniform combination therapy from the beginning of treatment. | Tae Jung Yun Jin Yong Jung Chang Ha Kim Soon Ho Um Hyonggin An Yeon Seok Seo Jin Dong Kim Hyung Joon Yim Bora Keum Yong Sik Kim Yoon Tae Jeen Hong Sik Lee Hoon Jai Chun Chang Duck Kim Ho Sang Ryu | 2012 | World Journal of Gastroenterology2012，18，47： | 19 |
| 8 | Modeling the climate effects of different subregional uplifts within the Himalaya-Tibetan Plateau on Asian summer monsoon evolution显示文摘Considering the different uplifting time of different subregions of the Himalaya-Tibetan Plateau(TP),a series of numerical simulations have been conducted with the Community Atmosphere Model(CAM4) developed at the National Center for Atmospheric Research to explore the effects of the phased tectonic uplift of the Himalaya-TP on the evolution of Asian summer monsoons.The results show that the uplifts of the Himalaya and northern TP significantly affect the evolutions of South Asian summer monsoon and northern East Asian summer monsoon respectively.That is,the tectonic uplift of the Himalaya intensifies the South Asian summer monsoon circulation and increases the precipitation in South Asia,whereas the uplift of the northern TP intensifies the northern East Asian summer monsoon circulation and increases the precipitation in northern East Asia.Compared with previous simulations,current comparative analyses of modeling results for different subregional uplifts within the Himalaya-TP help deepen our understanding of the evolutionary history of Asian monsoons. | ZHANG Ran 1,JIANG DaBang 1,2,3,LIU XiaoDong 4 & TIAN ZhiPing 2,5 1 Climate Change Research Center,Chinese Academy of Sciences,Beijing 100029,China 2 Nansen-Zhu International Research Centre,Institute of Atmospheric Physics,Chinese Academy of Sciences,Beijing 100029,China 3 Key Laboratory of Regional Climate-Environment Research for Temperate East Asia,Chinese Academy of Sciences,Beijing 100029,China 4 State Key Laboratory of Loess and Quaternary Geology,Institute of Earth Environment,Chinese Academy of Sciences,Xi’an 710075,China 5 Graduate University of Chinese Academy of Sciences,Beijing 100049,China | 2012 | Chinese Science Bulletin2012，57，35： | 14 |
| 9 | Acceptance of Chemo-prophylaxis for Latent Tuberculosis Infection among High School/College Student Contacts of Tuberculosis Patients in Shanghai, China显示文摘Student contacts of tuberculosis(TB)cases are susceptible to latent tuberculosis infection(LTBI),and chemo-prophylaxis can reduce the risk of active TB among them.This study aimed to assess | LI Yang ZHENG Yi Hui LU Li Ping YANG Mei Xia ZHOU Chang Ming YUAN Zheng An HU Yi XU Biao | 2018 | Biomedical and Environmental Sciences2018，31，4： | 12 |
| 10 | A Putative Calcium-Permeable Cyclic Nucleotide-Gated Channel,CNGC18,Regulates Polarized Pollen Tube Growth显示文摘一个集中尖端的 Ca^(2+) 坡度紧被联合到极化的花粉管生长,并且细胞外的 Ca^(2+) 的尖端局部性的流入为这个过程被要求。潜在的 Ca^(2+) 隧道的 Howeverthe 分子的身份和规定留下逃犯。现在的学习含有在极化的花粉管生长的 CNGC18 (周期的核苷酸门隧道 18 ) ,因为它的过去导致的表示更宽、更短的花粉管。而且,花粉管生长的 CNGC18 overexpressioninduced 去极被更低的细胞外的钙压制([Ca^(2+)]_( 前)) 。CNGC18 黄的荧光蛋白质(YFP ) 在花粉管的顶对明显的 post-Golgi 泡和质膜(下午) 优先地局部性。PMlocalization 被尖端局部性的 ROP1 发信号影响。野生型 ROP1 的表示或到下午的顶端的区域的 ROP1enhanced CNGC18-YFP 本地化的一种活跃形式,而表示 ofRopGAPI (ROP1 deactivator ) 堵住了下午本地化。这些结果支持一个角色在通过它在钙流入的调整的潜在的功能的极化的花粉管生长的规定的 forPM 局部性的 CNGC18。 | Fang Chang | 2007 | Journal of Integrative Plant Biology2007，49，8： | 12 |
| 11 | Distinct characteristics and new prognostic scoring system for Chinese patients with Waldenstr(o)m macroglobulinemia显示文摘 | Yi Shuhua Cui Rui Li Zengjun An Gang Qi Junyuan Zou Dehui Zhang Peihong Chen Huishu Wang Jianxiang Chang Hong Qiu Lugui | 2014 | Chinese Medical Journal2014，，12： | 12 |
| 12 | Primary scientific results of Chang'E-1 lunar mission显示文摘The strategic plan for the development of the unmanned Chinese Lunar Exploration Program is characterized by three distinct stages: 'orbiting around', 'landing on' and 'returning from' the Moon. The first Chinese lunar probe, Chang'E-1, which was successfully launched on October 24th, 2007 at Xichang Satellite Launch Center, and guided to crash on the Moon on March 1st, 2009, at 52.36°E, 1.50°S, in the north of Mare Fecunditatis, is the first step towards the 'orbiting around' stage. The Chang'E-1 mission lasted 495 days, exceeding the expected life-span by about four months. A total of 1.37 TB raw data was received from Chang'E-1. It was then processed into 4 TB scientific data products at various levels. Many scientific results have been obtained by analyzing these data, including especially the 'global lunar image from the first Chinese lunar explora- tion mission'. All scientific goals of Chang'E-1 have been achieved. It provides much useful materials for further advances of lunar sciences and planetary chemistry. Meanwhile, these results will serve as a firm basis for future Chinese lunar missions. | OUYANG ZiYuan1,2, LI ChunLai1, ZOU YongLiao1, ZHANG HongBo1, Lü Chang1, LIU JianZhong1, LIU JianJun1, ZUO Wei1, SU Yan1, WEN WeiBin1, BIAN Wei1, ZHAO BaoChang3, WANG JianYu4, YANG JianFeng3, CHANG Jin5, WANG HuanYu6, ZHANG XiaoHui7, WANG ShiJin7, WANG Min1, REN Xin1, MU LingLi1, KONG DeQing1, WANG XiaoQian1, WANG Fang1, GENG Liang1, ZHANG ZhouBin1, ZHENG Lei1, ZHU XinYing1, ZHENG YongChun1, LI JunDuo1, ZOU XiaoDuan1, XU Chun1, SHI ShuoBiao1, GAO YiFei1 & GAO GuanNan1 1 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China 2 Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China 3 Xi’an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi’an 710119, China 4 Shanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai 200083, China 5 Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008, China 6 Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China 7 Center for Space Science and Applied Research, Chinese Academy of Sciences, Beijing 100190, China | 2010 | Science China Earth Sciences2010，53，11： | 11 |
| 13 | Pb isotope geochemistry of lead, zinc, gold and silver deposit clustered region, Liaodong rift zone,northeastern China显示文摘Pb isotopic analyses were reported for sulfide and hydrothermal carbonate minerals and marble of the Xiquegou lead-zinc, the Zhenzigou zinc-lead and the Gaojiapuzi silver deposits from the Qingchengzi ore field and the Beiwagou zinc-lead deposit in the west, Proterozoic Liaodong rift zone. Pb isotopic ratios of the marble from the Qingchengzi ore field range from 18.24 to 30.63 for 206 Pb/204Pb, 15.59 to 17.05 for207Pb/204Pb and 37.43 to 38.63 for 208Pb/204Pb. The marble gives a Pb-Pb isochron age of 1822±92 Ma, which is interpreted as the age of the metamorphism of the marble. Ore Pb, including Pb of sulfide and hydrothermal car- bonate minerals, from the Qingchengzi ore field shows limited variation with 206 Pb/204Pb=17.66- 17.96, 207 Pb/204Pb=15.60-15.74 and 208Pb/204Pb=37.94-38.60. In contrast, ore Pb from the Beiwagou deposit gives different Pb isotopic ratios with 206Pb/204Pb=15.68-15.81, 207 Pb/204Pb= 15.34-15.45 and 208Pb/204Pb=35.30-35.68. Pb of all deposits from the Liaodong rift zone is derived from the upper crust. Ore Pb of the Qingchengzi deposits is derived from a young upper crust. The model Th/U ratios of 4.40 to 4.74 for ore Pb are significantly different from that of 1.7 to 4.4 given by the marble of the Qingchengzi ore field, suggesting that marble is not the source of the ore Pb. Ore Pb of the Beiwagou deposit is extracted from its source and the deposit is formed at the Paleoproterozoic era. Different Pb isotopic ratios of the Qingchengzi ore field and the Beiwagou deposit are due to different ages of the deposits and suggest that the two types of deposits are derived from different sources and are possibly formed by different ore-forming processes. | CHEN Jiangfeng1, YU Gang1, XUE Chunji2, QIAN Hui1, HE Jianfeng1, XING Zhi1 & ZHANG Xun1 1. School of Earth and Space Sciences, University of Science and Technology of China, Hefei 230026, China 2. Department of Geology, Chang’an University, Xi’an 710054, China | 2005 | Science China Earth Sciences2005，48，4： | 11 |
| 14 | 第四纪洞庭盆地临澧凹陷构造-沉积特征与环境演化显示文摘临澧凹陷为第四纪洞庭盆地西部的一个次级构造单元,居于武陵隆起和太阳山隆起之间。通过地表地质调查和钻孔资料对临澧凹陷第四纪构造-沉积特征与环境演化进行了研究。凹陷呈SN向,全长约55km,宽5~10km。受SN向雷公庙断裂和渐水断裂控制,凹陷中央形成断槽。凹陷分为南、北两段,其间前第四纪基底上凸。在凹陷北段,中央断槽内为最厚达270m的中更新世洞庭湖组,其主体为含砾粘土与粘土互层,顶部为粘土、含粉砂质粘土;断槽东面自西往东依次为中更新世中期白沙井组(含粉砂质)湖相粘土和更新世残坡积层;断槽西面依次为白沙井组(含粉砂质)湖相粘土和中更新世早期新开铺组砾石层,后者组成基座阶地。在凹陷南段,中央断槽内中更新世早期-中期沉积厚100m左右,顶部为湖相粘土,往下为冲积层;断槽东面发育白沙井组冲积砂砾层;断槽西面依次发育白沙井组和新开铺组,前者自下而上分别为冲积含砾砂层和湖相粘土,后者为冲积砂砾层并组成堆积阶地。根据地貌、沉积和断裂特征,重塑临澧凹陷构造活动与环境演化过程:中更新世早期渐水由西部进入临澧凹陷区后向南汇入沅水,于凹陷南段形成冲积层;同时来自西面山地的次级水系于凹陷西缘形成砾石层。中更新世中期受两侧正断裂控制中央断槽开始形成并接受沉积,其中北段断槽形成相对封闭的湖泊,南段断槽为河流环境;与此同时,断槽西面相对抬升并遭受剥蚀,稍后南段尚形成白沙井组冲积层。中更新世中后期临澧凹陷南、北段均产生扩张并处于湖泊环境,于中央断槽和两侧边缘形成泥质沉积。中更新世晚期构造反转,临澧凹陷整体抬升、遭受剥蚀且地表粘土发生网纹化,同时具有自西向东的掀斜,造成凹陷西侧水系更为发育。晚更新世因切割和剥蚀而形成丘岗地貌,并形成改造型或坡积型的褐色铁锰裂隙土。临澧凹陷的形成受控于区域伸展断陷背景,并可能与断裂走滑拉分有关。 | 柏道远 刘波 李长安 马铁球 王先辉 彭云益 Chang'an | 2010 | 山地学报2010，28，6： | 11 |
| 15 | Influence of differential settlement on pavement structure of widened roads based on large-scale model test显示文摘This study introduced at first the background of numerous highway widening projects that have been developed in recent years in China.Using a large ground settlement simulator and a fiber Bragg grating (FBG) strain sensor network system,a large-scale model test,with a similarity ratio of 1:2,was performed to analyze the influence of differential settlement between new and old subgrades on pavement structure under loading condition.The result shows that excessive differential settlement can cause considerable tensile strain in the pavement structure of a widened road,for which a maximum value (S) of 6 cm is recommended.Under the repetitive load,the top layers of pavement structure are subjected to the alternate action of tensile and compressive strains,which would eventually lead to a fatigue failure of the pavement.However,application of geogrid to the splice between the new and the old roads can reduce differential settlement to a limited extent.The new subgrade of a widened road is vulnerable to the influence of dynamic load transferred from the above pavement structures.While for the old subgrade,due to its comparatively high stiffness,it can well spread the load on the pavement statically or dynamically.The test also shows that application of geogrid can effectively prevent or defer the failure of pavement structure.With geogrid,the modulus of resilience of the subgrade is increased and inhomogeneous deformation can be reduced;therefore,the stress/strain distribution in pavement structure under loading condition becomes uniform.The results obtained in this context are expected to provide a helpful reference for structural design and maintenance strategy for future highway widening projects. | Xiaolin Weng1,2,Wei Wang3 1 Key Laboratory for Special Area Highway Engineering of Ministry of Education,Chang’an University,Xi’an,710064,China 2 CCCC First Highway Consultants Co.,Ltd.,Xi’an,710068,China 3 Henan Vocational and Technical College of Communications,Zhengzhou,450005,China | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011，3，1： | 11 |
| 16 | Deep-learning-based phase control method for tiled aperture coherent beam combining systems显示文摘We incorporate deep learning(DL)into tiled aperture coherent beam combining(CBC)systems for the first time,to the best of our knowledge.By using a well-trained convolutional neural network DL model,which has been constructed at a non-focal-plane to avoid the data collision problem,the relative phase of each beamlet could be accurately estimated,and then the phase error in the CBC system could be compensated directly by a servo phase control system.The feasibility and extensibility of the phase control method have been demonstrated by simulating the coherent combining of different hexagonal arrays.This DL-based phase control method offers a new way of eliminating dynamic phase noise in tiled aperture CBC systems,and it could provide a valuable reference on alleviating the long-standing problem that the phase control bandwidth decreases as the number of array elements increases. | Tianyue Hou Yi An Qi Chang Pengfei Ma Jun Li Dong Zhi Liangjin Huang Rongtao Su Jian Wu Yanxing Ma Pu Zhou | 2019 | High Power Laser Science and Engineering2019，7，4： | 10 |
| 17 | Rules of Meridians and Acupoints Selection in Treatment of Parkinson’s Disease Based on Data Mining Techniques显示文摘Objective:To help selecting appropriate meridians and acupoints in clinical practice and experimental study for Parkinson’s disease(PD),the rules of meridians and acupoints selection of acupuncture and moxibustion were analyzed in domestic and foreign clinical treatment for PD based on data mining techniques.Methods:Literature about PD treated by acupuncture and moxibustion in China and abroad was searched and selected from China National Knowledge Infrastructure and MEDLINE.Then the data from all eligible articles were extracted to establish the database of acupuncture-moxibustion for PD.The association rules of data mining techniques were used to analyze the rules of meridians and acupoints selection.Results:Totally,168 eligible articles were included and 184 acupoints were applied.The total frequency of acupoints application was 1,090 times.Those acupoints were mainly distributed in head and neck and extremities.Among all,Taichong(LR 3),Baihui(DU 20),Fengchi(GB 20),Hegu(LI 4)and Chorea-tremor Controlled Zone were the top five acupoints that had been used.Superior-inferior acupoints matching was utilized the most.As to involved meridians,Du Meridian,Dan(Gallbladder)Meridian,Dachang(Large Intestine)Meridian,and Gan(Liver)Meridian were the most popular meridians.Conclusions:The application of meridians and acupoints for PD treatment lay emphasis on the acupoints on the head,attach importance to extinguishing Gan wind,tonifying qi and blood,and nourishing sinews,and make good use of superior-inferior acupoints matching. | LI Zhe HU Ying-yu ZHENG Chun-ye SU Qiao-zhen AN Chang LUO Xiao-dong LIU Mao-cai | 2020 | Chinese Journal of Integrative Medicine2020，26，8： | 9 |
| 18 | Effect of Optimized Concentrations of Basic Fibroblast Growth Factor and Epidermal Growth Factor on Proliferation of Fibroblasts and Expression of Collagen: Related to Pelvic Floor Tissue Regeneration显示文摘 | Yuan-Yuan Jia Jing-Yi Zhou Yue Chang Fang An Xiao-Wei Li Xiao-Yue Xu Xiu-Li Sun Chun-Yang Xiong Jian-Liu Wang | 2018 | Chinese Medical Journal2018，，17： | 9 |
| 19 | Efficient one-pot synthesis of n-butyl levulinate from carbohydrates catalyzed by Fe_2(SO_4)_3显示文摘Butyl levulinate(BL) is a promising new candidate as diesel fuel and fuel additive. In this study, an efficient process for a one-pot synthesis of BL from biomass-derived carbohydrates in butanol medium with the catalysis of metal sulfates was developed. The catalytic activity of a series of metal sulfates for the synthesis of BL from fructose was investigated. Among various metal sulfates, ferric sulfate Fe_2(SO_4)_3 was found to be the most efficient catalyst, which gave a remarkably high BL yield of 62.8 mol% under the conditions of 463 K, 3 h, a catalyst dosage of 5.0 g/L, and fructose concentration of 25 g/L. Different carbohydrates including glucose, cellulose, inulin and sucrose were also used for one-pot synthesis of BL with the catalysis of Fe_2(SO_4)_3, showing the yields of 39.6, 30.5, 56.6 and 50.1 mol%, respectively. In addition,the recycling and reuse of Fe_2(SO_4)_3 was studied by characterizing them using powder X-ray diffraction(XRD), scanning electron microscope(SEM), X-ray photoelectron spectroscopy(XPS). A plausible reaction pathway for the one-pot synthesis of BL from fructose was proposed. This study provides a facile and feasible way for the synthesis of BL from biomass. | Ran An Guizhuan Xu Chun Chang Jing Bai Shuqi Fang | 2017 | Journal of Energy Chemistry2017，26，3： | 8 |
| 20 | Effects of bile acids on proliferation and ultrastructural alteration of pancreatic cancer cell lines显示文摘AIM: Pancreatic cancer in the head is frequently accompanied by jaundice and high bile acid level in serum. This study focused on the direct effects of bile acids on proliferation and ultrastructural alteration of pancreatic cancer.METHODS: Pancreatic cancer cell lines PANC-1, MIA PaCa2 and PGHAM-1 were explored in this study. The cell lines were cultured in media supplemented with certain bile acids,CA, DCA, LCA, TCDC, TDCA and GCA. Their influence on cell growth was measured with MTT assay after 72 h of incubation. Cell cycles of PANC-1 cells in 40 μM of bile acids media were analyzed by flow cytometry. Ultrastructural alteration of PANC-1 cells induced by DCA was observed using scanning and transmission electron microscope (SEM and TEM).RESULTS: At various concentrations of bile acids and incubation time, no enhanced effects of bile acids on cell proliferation were observed. Significant inhibitory effects were obtained in almost all media with bile acids. DCA and CA increased the percentage of G0+G1 phase cells, while GCA and TDCA elevated the S phase cell number. After 48 h of incubation in DCA medium, PANC-1 cells showed some structural damages such as loss of their microvilli and vacuolization of organelles in cytoplasm.CONCLUSION: Bile acids can reduce proliferation of pancreatic cancer cells due to their direct cytotoxicity. This result implies that elevation of bile acids in jaundiced serum may inhibit pancreatic cancer progression. | Zheng Wu Yi Lü Bo Wang Chang Liu Zuo-Ren Wang Department of Hepatobiliary Surgery,The First Hospital of Xi’an Jiaotong University,Xi’an 710061,Shaanxi Province,China | 2003 | World Journal of Gastroenterology2003，9，12： | 8 |
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