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| 1 | Management of oligometastatic non-small cell lung cancer patients:Current controversies and future directions显示文摘Oligometastatic non-small cell lung cancer(NSCLC)describes an intermediate stage of NSCLC between localized and widely-disseminated disease.This stage of NSCLC is characterized by a limited number of metastases and a more indolent tumor biology.Currently,the management of oligometastatic NSCLC involves radical treatment(radiotherapy or surgery)that targets the metastatic lesions and the primary tumor to achieve disease control.This approach offers the potential to achieve prolonged survival in patients who,in the past,would have only received palliative measures.The optimal therapeutic strategies for the different scenarios of oligometastatic disease(intracranial vs extracranial disease,synchronous vs metachronous)remain undefined.Given the lack of head-to-head studies comparing radiotherapy to surgery in these patients,the decision to apply surgery or radiotherapy(with or without systemic treatment)must be based on prognostic factors that allow us to classify patients.This classification will allow us to select the most appropriate therapeutic strategy on an individualized basis.In the future,the molecular or microRNA profiles will likely improve the treatment selection process.The objective of the present article is to review the most relevant scientific evidence on the management of patients with oligometastatic NSCLC,focusing on the role of radiotherapy and surgery.We also discuss areas of controversy and future directions. | Felipe Counago Javier Luna Luis Leonardo Guerrero Blanca Vaquero María Cecilia Guillén-Sacoto Teresa González-Merino Begona Taboada Verónica Díaz Belén Rubio-Viqueira Ana Aurora Díaz-Gavela Francisco JoséMarcos Elia del Cerro | 2019 | World Journal of Clinical Oncology2019，10，10： | 5 |
| 2 | Magnetic resonance imaging for prostate cancer before radical and salvage radiotherapy: What radiation oncologists need to know显示文摘External beam radiotherapy(EBRT) is one of the principal curative treatments for patients with prostate cancer(PCa). Risk group classification is based on prostate-specific antigen(PSA) level, Gleason score, and T-stage. After risk group determination, the treatment volume and dose are defined and androgen deprivation therapy is prescribed, if appropriate. Traditionally, imaging has played only a minor role in T-staging due to the low diagnostic accuracy of conventional imaging strategies such as transrectal ultrasound, computed tomography, and morphologic magnetic resonance imaging(MRI). As a result, a notable percentage of tumours are understaged, leading to inappropriate and imprecise EBRT. The development of multiparametric MRI(mp MRI), an imaging technique that combines morphologic studies with functional diffusion-weighted sequences and dynamic contrastenhanced imaging, has revolutionized the diagnosis and management of PCa. As a result, mpM RI is now used in staging PCa prior to EBRT, with possible implications for both risk group classification and treatment decisionmaking for EBRT. mpM RI is also being used in salvageradiotherapy(SRT), the treatment of choice for patients who develop biochemical recurrence after radical prostatectomy. In the clinical context of biochemical relapse, it is essential to accurately determine the site of recurrence-pelvic(local, nodal, or bone) or distant-in order to select the optimal therapeutic management approach. Studies have demonstrated the value of mpM RI in detecting local recurrences-even in patients with low PSA levels(0.3-0.5 ng/m L)-and in diagnosing bone and nodal metastasis. The main objective of this review is to update the role of mpM RI prior to radical EBRT or SRT. We also consider future directions for the use and development of MRI in the field of radiation oncology. | Felipe Cou?ago Gemma Sancho Violeta Catalá Diana Hernández Manuel Recio Sara Montemui?o Jhonathan Alejandro Hernández Antonio Maldonado Elia del Cerro | 2017 | World Journal of Clinical Oncology2017，8，4： | 4 |
| 3 | Clinical features and radiological manifestations of COVID-19 disease显示文摘Coronavirus disease 2019(COVID-19)was discovered after unusual cases of severe pneumonia emerged in December 2019 in Wuhan Province(China).Coronavirus is a family of single-stranded RNA viruses.Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is transmitted from person to person.Although asymptomatic individuals can transmit the virus,symptomatic patients are more contagious.The incubation period ranges from 3-7 d and symptoms are mainly respiratory,including pneumonia or pulmonary embolism in severe cases.Elevated serum levels of interleukins(IL)-2,IL-6,IL-7 indicate the presence of cytokine release syndrome,which is associated with disease severity.The disease has three main phases:Viral infection,pulmonary involvement,and hyperinflammation.To date,no treatment has proved to be safe or effective.Chest X-ray and computed tomography(CT)are the primary imaging tests for diagnosis of SARS-CoV-2 pneumonia,follow-up,and detection of complications.The main radiological findings are ground-glass opacification and areas of consolidation.The long-term clinical course is unknown,although some patients may develop pulmonary fibrosis.Positron emission tomography-computed tomography(PETCT)is useful to assess pulmonary involvement,to define the affected areas,and to assess treatment response.The pathophysiology and clinical course of COVID-19 infection remain poorly understood.However,patterns detected on CT and PETCT may help to diagnose and guide treatment.In this mini review,we analyze the clinical manifestations and radiological findings of COVID-19 infection. | Pedro Landete Carlos Andres Quezada Loaiza Beatriz Aldave-Orzaiz Susana Hernandez Muniz Antonio Maldonado Enrique Zamora Allan Charles Sam Cerna Elia del Cerro Raquel Cano Alonso Felipe Counago | 2020 | World Journal of Radiology2020，12，11： | 2 |
| 4 | Effect of gap size and forest type on mineral nitrogen forms under different soil properties显示文摘Gaps play a key role in forest ecosystem development and result from either natural processes or targeted forest management activities.The aim of this study was to investigate the interrelationships of soil properties in each of three forest types and two treatments,and to identify factors that influence levels of soil mineral nitrogen forms.The relation between mineral nitrogen and factors of soil parameters and stand type(European beech,Norway spruce,mixed stand)categories were investigated.The spruce forest type stored significant nitrogen in both mineral forms of nitrogen.Moreover,there was a significant linear dependence between N-NO3^-(nitrate anion)concentrations and cation exchange capacity(CEC)parameters such as base cation contents(S-CEC)and potential ureolytic activities(UreasePot),as well as between N-NH4^+(ammonium cation)concentrations and both hydrolytic acidities(Ha-CEC)and ureolytic activities.The dependence of N-NO3^-concentrations on S-CEC contents and UreasePot was negative,especially in adjacent stand.The dependence of N-NH4^+concentrations on Ha-CEC and UreasePot was week in the beech and mixed forest types while it was significantly positive in the spruce forest type. | Ales Kucera Ladislav Holik Elena Munoz Cerro Jan Petricek | 2020 | Journal of Forestry Research2020，31，2： | 2 |
| 5 | A new procedure for obtaining photoreceptor cells for transplantation显示文摘 | Liang FQ Bassage SD del Cerro C | 1994 | Invest Ophthalmol Vis Sci1994，，： | 1 |
| 6 | Simultaneous detection of Aeromonas salmonicida , Flavobacterium psychrophilum , and Yersinia ruckeri , three major fish pathogens, by multiplex PCR显示文摘 | del Cerro A Marquez I Guijarro J A | 2002 | Appl Environ Microbiol2002，68，10： | 1 |
| 7 | Balloon angioplasty for native coarctation in children:immediate and medium-term results显示文摘 | Cerro D Aurora FR Benito F | 2005 | Rev Esp Cardiol2005，58，： | 1 |
| 8 | Interpersonal Aggression and the Type A Coronary-Prone Behavior Pattern:A Theoretical Distinction and Practical Implications显示文摘 | Strube M J Turner D W Cerro D Stevens J & Hinchey F | 1984 | Journal of Personality and Social Psychology1984，47，： | 1 |
| 9 | Sonographic diagnosis of intusus- scep-tions in adults 显示文摘 | Cerro P Macrini L Poreari P | 2000 | Abdominal Imaging2000，25，： | 1 |
| 10 | A new procedure for evaluating smoothness of corneal surface following 193-nanometer excimer laser ablation显示文摘 | Liang FQ Geasey SD del Cerro M | 1992 | Refract Corneal Surg1992，8，6： | 1 |
| 11 | Chem Eng显示文摘 | Boeys C del Cerro M C Pyle D L | 1987 | (65): 218-2231987，，65： | 1 |
| 12 | Effects of thalidomide on HIV - associated wasting syndrome; a randomized, double - blind, placebo - controlled clinical trial显示文摘 | Sierra Madero JG Martinez del Cerro V | 1996 | AIDS1996，10，： | 1 |
| 13 | Computed tomography enteroclysis in comparison with ileoscopy in patients with Crohn's disease显示文摘 | Cerro P Zullo A | 2003 | Int J Colorectal Dis2003，18，2： | 1 |
| 14 | Immune thrombocytopenic purpura as presenting form of miliary tuberculosis显示文摘 | Perez de Llano LA Soilan del Cerro JL Garcia Pais MJ | 1998 | Arch Bronconeumol1998，34，8： | 1 |
| 15 | A new procedure for obtaining photoreceptor cells for transplantation显示文摘 | Liang FQ Bassage SD del Cerro C | 1994 | Invest Ophthalmol Vis Sci1994，，： | 1 |
| 16 | The monolith froth reac- tor:residence time modeling and analysis显示文摘 | Thulasidas T C Cerro R L Abraham M A | 1995 | Chem Eng Res Des1995，73，3： | 1 |
| 17 | Modelling the daily reference evapotranspiration in semi-arid region of South India: A case study comparing ANFIS and empirical models显示文摘The estimation of evapotranspiration(ETo)is one of the main tools for the control of crop growth and to make a rational use of water resources.To estimate this parameter accurately,it is necessary to have a daily measurement of four meteorological variables,these are:temperature,solar radiation,relative humidity and wind speed.It is not always possible to count on all the variables,that is why there are empirical methods that use a limited number of variables that make an approximate estimate of the ETo value.Each of these models are applicable to different regions with completely different climates.In this paper,a study has been carried out to define the model of ETo estimation that best adapts to the semi-arid region in South India.Two different datasets for the same period from different meteorological stations were used.In addition to the empirical methods for estimating ETo,computer models ANFIS(Adaptive Neuro-Fuzzy Inference System)were implemented.These models consist in the future estimation of a certain parameter by using current variables and a history of variables and past results.The results of this work show that ANFIS 11 model makes the best estimate with RMSD=0.002 and r=0.999.The RITCHIE method is the most suitable empirical model for this region,which reaches RMSD=0.507 and r=0.851.In addition,ranking of equations is elaborated for both datasets for daily estimates of ETo.Finally,comparison is made with the results for each case and thus confirm or reject the convenience of one model over the rest.To achieve this,a series of statistical indicators were used:Index of agreement(d),MAE(Mean absolute error),SEE(Standard error of estimate)and RMSD(Root mean square difference).Moreover,a sensitivity analysis was performed in order to compare and show the stability of the best models when an error is introduced within the input parameters.In this case,the empirical models demonstrate a better performance than the ANFIS models.This work demonstrates that the Ritchie method is a good estimator of the ETo value for a semi-arid region in southern India.In addition,the results of the ANFIS models are promising and could be used as estimation methods. | Ramiro T.Gonzalez del Cerro M.S.P Subathra Nallapaneni Manoj Kumar Sebastian Verrastro S.Thomas George | 2021 | Information Processing in Agriculture2021，8，1： | 1 |
| 18 | Virulence and antimicrobial-resistance gene profiles determined by PCR- based procedures for Salmonella isolated from samples of animal origin显示文摘 | Del Cerro A Soto S M Mendoza M C | 2003 | Food Microbiol2003，20，4： | 1 |
| 19 | Cerro Negro bitumen degradation by a consortium of marine benthic microorganisms 显示文摘 | POTTER T L CERRO D B | 2001 | Environmental Science & Technology2001，35，1： | 1 |
| 20 | Pathology, isolation and molecular characterization of a ranavirus from the common mid- wife toad Alytes obstetricans on the Iberian Peninsula显示文摘 | Balseiro A Dalton K P Cerro A | 2009 | Dis Aquat Org2009，84，： | 1 |
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