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| 1 | JNKs,insulin resistance and inflammation:A possible link between NAFLD and coronary artery disease显示文摘The incidence of obesity has dramatically increased in recent years.Consequently,obesity and associated disorders such as nonalcoholic fatty liver disease constitute a serious problem.Therefore,the contribution of adipose tissue to metabolic homeostasis has become a focus of interest.In this review,we discuss the latest discoveries that support the role of lipids in nonalcoholic fatty liver disease.We describe the common mechanisms(cJun aminoterminal kinases,endoplasmic reticulum stress,unfolded protein response,ceramide,lowgrade chronic inflammation)by which lipids and their derivatives impair insulin responsiveness and contribute to inflammatory liver and promote plaque instability in the arterial wall.Presenting the molecular mechanism of lipid activation of proinflammatory pathways,we attempt to find a link between nonalcoholic fatty liver disease,metabolic syndrome and cardiovascular diseases.Describing the common mechanisms by which lipid derivatives,through modulation of macrophage function,promote plaque instability in the arterial wall,impair insulin responsiveness and contribute to inflammatory liver and discussing the molecular mechanism of lipid activation of proinflammatory pathways,the key roles played by the proliferatoractivated receptor and liver X receptorα,nuclear receptorslipid sensors that link lipid metabolism and inflammation,should be emphasized.Further studies are warranted of antiinflammatory drugs such as aspirin,antiinterleukin6 receptors,immunemodulators(calcineurin inhibitors),substances enhancing the expression of heat shock proteins(which protect cells from endoplasmic reticulum stressinduced apoptosis),and anticJun aminoterminal kinases in welldesigned trials to try to minimize the high impact of these illnesses,and the different expressions of the diseases,on the whole population. | Giovanni Tarantino Armando Caputi | 2011 | World Journal of Gastroenterology2011，17，33： | 21 |
| 2 | Longitudinal effects of theory of mind on later peer relations: The role of prosocial behavior 显示文摘 | Caputi M Lecce S Pagnin A | 2012 | Developmental Psychology2012，48，1： | 1 |
| 3 | Ca2 -- buffer saturation underlies paired pulse facilitation in calbindin- D28k-containing terminals显示文摘 | Blatow M Caputi A Burnashev N | 2003 | Neuron2003，38，： | 1 |
| 4 | Influ- ence of surface treatments on the flexural properties of fiber posts显示文摘 | D'Arcangelo C D'Amario M Vadini M De Angelis F Caputi S | 2007 | J Endod2007，33，7： | 1 |
| 5 | Endoscopic implant evaluation and capsulotomy显示文摘 | Flowers RS | 1994 | Plast Reconstr Surg1994，93，5： | 1 |
| 6 | Allele and genotype fre- quencies of CYP2Cg, CYtr2C19 and CYtr2D6 in an Italian population 显示文摘 | Seordo MG Caputi A_P D' Arrigo C | 2004 | Pharmaeol Rea2004，50，2： | 1 |
| 7 | Bacterial adhesion on commercially pure titanium and zirconium oxide disks:an in vivo human study显示文摘 | Scarano A Piattelli M Caputi S | 2004 | J Periodontol2004，75，2： | 1 |
| 8 | Ethanol induces epigenetic modulation of prodynorphin and pronociceptin gene expression in the rat amygdala complex显示文摘 | D′addario C Caputi FF Ekstr?m TJ Di Benedetto M Maccarrone M Romualdi P | 2013 | J Mol Neurosci2013，49，2： | 1 |
| 9 | Residual shunt after patent foramen ovale closure:preliminary results from italian patent foramen ovalesurvey显示文摘 | Caputi L Butera G Anzola G P | 2013 | J Stroke Cerebrovasc Dis2013，22，7： | 1 |
| 10 | Antioxidant Therapy:A New Pharmacological Approach in Stroke,Inflammation and Ischemia-reperfusion Injury显示文摘 | CUZZOCREA S RILEY DP CAPUTI AP | 2001 | Pharmacol Rev(S0031-6979)2001，53，： | 1 |
| 11 | CaMKII-dependent phosphorylation of NR2A and NR2B is decreased in animals characterized by hippocampal damage and impaired LTP显示文摘 | Gardoni F Cimino M | 1999 | Eur J Neurosci1999，11，1： | 1 |
| 12 | 5-lipoxygenase modulates the alteration of paracellular barrier function in mice ileum during experimental colitis显示文摘 | Mazzon E Sautebin L Caputi A P | 2006 | Shock2006，25，4： | 1 |
| 13 | Tailored anteromedial lobectomy in the treatment of refractory epilepsy of the temporal lobe : long term surgical outcome and predictive factors 显示文摘 | Roberti F Potolicchio SJ Caputy AJ | 2007 | Clin Neurol Neurosurg2007，109，2： | 1 |
| 14 | hnRNP A1:the Swiss army knife of gene expression 显示文摘 | Jean-Philippe J Paz S Caputi M | 2013 | International journal of molecular sciences2013，14，18： | 1 |
| 15 | Relationships between self-rated health,quality of life and sleep duration in middle aged and elderly Australians显示文摘 | Magee CA Caputi P Iverson DC | 2011 | Sleep Medicine2011，，4： | 1 |
| 16 | The experience of recovery fromschizophrenia:Towards an empirically validated stage model显示文摘 | Andresen R Oades L Caputi P | 2003 | Australia and New Zealand Journal of Psychiatry2003，37，5： | 1 |
| 17 | Determination of the RNA binding specificity of the heterogeneous nuclear ribonucleoprotein (hnRNP) H/H'/F/2H9 family显示文摘 | CAPUTI M ZAHLER A Z | 2001 | J Biol Chcm2001，276，47： | 1 |
| 18 | Therapeutic blockade of greater occipital and supraorbital nerves in migraine patients显示文摘 | Caputi CA Firetto V | 1997 | Headache1997，37，： | 1 |
| 19 | Exploring the relationship between work stress, years of experience and emotional competency using a sample of Australian mental health nurses 显示文摘 | Humpel N Caputi P Dip G | 2001 | Journal of Psychiatric and Mental Health Nursing2001，8，5： | 1 |
| 20 | Prognostic role of cyclin DI in lung cancer, relationship to proliferating cell nuclear antigen显示文摘 | Caputi M Groeger AM Esposito V | 1999 | Am J Respir Cell Mol Biol1999，20，4： | 1 |
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