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	题名	作者	年代	出处	被引量
1	Evidence for altered thiamine metabolism in diabetes: Is there a potential to oppose gluco- and lipotoxicity by rational supplementation?显示文摘Growing prevalence of diabetes(type 2 as well as type 1) and its related morbidity due to vascular complications creates a large burden on medical care worldwide. Understanding the molecular pathogenesis of chronic micro-, macro- and avascular complications mediated by hyperglycemia is of crucial importance since novel therapeutic targets can be identified and tested. Thiamine(vitamin B1) is an essential cofactor of several enzymes involved in carbohydrate metabolism and published data suggest that thiamine metabolism in diabetes is deficient. This review aims to point out the physiological role of thiamine in metabolism of glucose and amino acids, to present overview of thiamine metabolism and to describe the consequences of thiamine deficiency(either clinically manifest or latent). Furthermore, we want to explain why thiamine demands are increased in diabetes and to summarise data indicating thiamine mishandling in diabetics(by review of the studies mapping the prevalence and the degree ofthiamine deficiency in diabetics). Finally, we would like to summarise the evidence for the beneficial effect of thiamine supplementation in progression of hyperglycemia-related pathology and, therefore, to justify its importance in determining the harmful impact of hyperglycemia in diabetes. Based on the data presented it could be concluded that although experimental studies mostly resulted in beneficial effects, clinical studies of appropriate size and duration focusing on the effect of thiamine supplementation/therapy on hard endpoints are missing at present. Moreover, it is not currently clear which mechanisms contribute to the deficient action of thiamine in diabetes most. Experimental studies on the molecular mechanisms of thiamine deficiency in diabetes are critically needed before clear answer to diabetes community could be given.	Luká? Pácal Katarína Kuricová Katerina Kaňková	2014	World Journal of Diabetes2014，5，3：	3
2	Scanning electron microsco- py evaluation of the bonding mechanism of a self - etching primer on enamel显示文摘	Cal -Neto J P Mendes -Miguel J A	2006	Angle Orthod2006，76，1：	1
3	Solid substrate pro-duction of Epicoccum nigrum conidia for biologicalcontrol of brown rot on stone fruits显示文摘	Larena I De Cal A Melgarejo P	2004	InternationalJournal of Food Microbiology2004，94，2：	1
4	Accumulation of specific dissolved and colloidal substances during white water recycling affect paper properties显示文摘	Zhang X Beatson R P Cal Y J	1999	JPPS1999，25，6：	1
5	Segmentalhyperperfusion in lobar pneumonia visualized withrespiratory-gated four-dimensional pulmonary perfusionpositron emission tomography-computed tomography显示文摘	Hofman MS Cal lahan J Eu P	2014	AmJ Respir Crit Care Med2014，189，1：	1
6	A human homologue of the D10 - sophila Toll protein signals activation of adaptive im- munity 显示文摘	Medzhitov R Preston -Hurlburt P Janeway CAl	1997	Nature1997，388，：	1
7	Epidemiology of vitiligo in the French West Indies (Isle of Martinique)显示文摘	Boisseau-Garsaud AM Garsaud P Calès-Quist D	2000	Int J Dermatol2000，39，1：	1
8	Destruction of benzene with non-thermal plasma in dielectric discharge reactors 显示文摘	Mark P Cal Martin Schluep	2001	Environmental Progress2001，20，3：	1
9	The fate of residual lS N- labelled fertilizer in arable soils: its availability to subsequent crops and retention in soil 显示文摘	Macdon-ld A Pouhon P Stockdale E et cal	2002	Plant Soil2002，246，1：	1
10	Influence of Mn addition on microstructure and phaseformation of spray-deposited Al-25Si-xFe->Mn alloy 显示文摘	HUANG H J CAl Y H CUI H HUANG J F HE J P ZHANG JS	2009	Materials Science and Engineering A2009，502，12：	1
11	High temperature hydrogen sulfide adsorption on activated carbon Ⅱ Effects of gas temperature,gas pressure and sorbent regeneration显示文摘	CAL M P STRICKLER B W LIZZIO A A GANGWAL S K	2000	Carbon2000，38，13：	1
12	Improved methods for solving monomer partitioning in emulsion copolymer systems显示文摘	De La Cal J C Asua J M	1994	Appl Polym Sci1994，51，：	1
13	Accumulation of specific dissolved and colloidal substances during white water recycling affect paper propertiee显示文摘	Zhang X Beatson R P Cal Y J	1999	Journal of Pulp and Paper Science1999，25，6：	1
14	Comparison of digital and spectrophotometric measurements of colour shade guides显示文摘	Cal E Guneri P Kose T	2006	J Oral Rehabil2006，33，3：	1
15	Supplementary concentrate type af ects nitrogen excretion of grazing dairy cows显示文摘	Mul igan F J Dil on P Cal an J J		0，，10：	1
16	Carson TUMOR necrosis factor-a conveting enzyme/ADAM17 mediate MUC1 sheding显示文摘	Amantha T Cal P B Daniel D	2003	The Jour of Biological Chemistry2003，278，5：	1
17	Using collagen fiber as a template to synthe?size TiO2 and Fexl TiO2 nanofibers and their catalytic behaviors on the visible light-assisted degradation of orange II显示文摘	CAl L LIAO X P SHI B	2010	Ind Eng Chem Res2010，49，7：	1
18	Application of a digital tech-nique in evaluating the reliability of shade guides显示文摘	Sonngelen M Guneri P	2004	J Oral Rehabil2004，31，5：	1
19	Impact of stator windings and end-bells on resonant frequencies and mode shapes of switched reluctance motors 显示文摘	CAl W Pillay P Tang Z	2002	IEEE Trans on Indu Appl2002，38，4：	1
20	Genetic risk factors for diabetic nephropathy on chromosomes 6p and 7q identified by the set-association approach显示文摘	KankováK StejskalováA Pácal L	2007	Diabetologia2007，50，5：	1

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