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| 1 | Intraoperative acidosis is a new predictor for postoperative pancreatic fistula after pancreaticoduodenectomy显示文摘BACKGROUND:Early diagnosis of postoperative pancreatic fistula(POPF) is important for proper interventions.The preoperative,intraoperative and early postoperative biochemical markers have predictive value of POPF.The present study was to evaluate several simple biochemical parameters in the prediction of POPF.METHODS:Patients who underwent pancreaticoduodenectomy in our center between 2006 and 2015 were reviewed retrospectively.Preoperative and early postoperative biochemical parameters were evaluated.Additionally,the relationship between POPF and p H and lactate level at the end of surgery were analyzed,and neutrophil-to-lymphocyte ratio(NLR),plateletto-lymphocyte ratio(PLR),and red cell distribution widthto-platelet ratio(RPR) were calculated for postoperative days(PODs) 1 and 3.Diagnosis and grading of POPF were performed according to the standards of the International Study Group on Pancreatic Fistula.The patients were divided into two groups:Group 1 with no fistula or grade-A fistula; group 2 with grade-B or-C fistula.These simple biochemical markers were then compared between the two groups.RESULTS:Serum amylase level was significantly higher at POD3,and p H level was significantly lower at the end of operation in group 2 compared with those in group 1.However,the serum amylase was below the upper limit of normal serum level and therefore,the difference was not significant in clinical practice.Receiver operating charecteristic curve analysis showed that p H level was a reliable predictor of POPF(area under the curve:0.713; 95% CI:0.573-0.853).CONCLUSIONS:A low p H level at the end of pancreaticoduodenectomy was a risk factor of POPF.NLR,PLR,and RPR had no predictive value of POPF after pancreaticoduodenectomy. | Erdem Kinaci Mert Mahsuni Sevinc Abdulkerim Ozakay Savas Bayrak Ekrem Cakar Serkan Sari | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，3： | 7 |
| 2 | Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid显示文摘Addiction to synthetic cannabinoids(SCs) is a growing social and health problem worldwide. Chronic use of SCs may cause adverse effects in the gastrointestinal system. We describe a very rare case of acute gastric dilatation(AGD) and hepatic portal venous gas(HPVG),with findings of acute abdomen resulting from chronic use of a SC, Bonzai. AGD and HPVG were detected by computerized tomography examination. Patchy mucosal ischemia was seen in endoscopic examination. Despite the findings of an acute abdomen, a non-surgical approach with nasogastric decompression, antibiotic therapy, and close radiologic and endoscopic followup was preferred in the presented case. Clinical and radiologic findings decreased dramatically on the first day, and endoscopic findings gradually disappeared over 7 d. In conclusion, this case shows that chronic use of a SC may cause AGD and accompanying HPVG,which can be managed non-surgically despite the findings of acute abdomen. | Mert Mahsuni Sevinc Erdem Kinaci Savas Bayrak Aytul Hande Yardimci Ekrem Cakar Hasan Bektas | 2015 | World Journal of Gastroenterology2015，21，37： | 3 |
| 3 | Oxygenation response to a recruitment maneuver during supine and prone positions in an oleic acid-induced lung injury model 显示文摘 | Cakar N der Kloot TV Youngblood M | 2000 | Am J Respir Crit Care Med2000，161，6： | 1 |
| 4 | Metabolic engineering of yeast:the perils of auxotrophic hosts显示文摘 | Cakar Z P Sauer U Bailey J E | 1999 | Biotechnol Lett1999，21，： | 1 |
| 5 | Complications associated with the ball,bar and Locator attachments for implant-supported overdentures显示文摘 | Cakarer S Can T Yaltirik M | | 0，，7： | 1 |
| 6 | Detection of prostatic carcinoma:the role of TRUS,TRUS guided biopsy,digital rectal examination,PSA and PSA density显示文摘 | Men S Cakar B Conkbayir I | 2001 | J Exp Clin Cancer Res2001，20，： | 1 |
| 7 | Nonconvulsive stalus epilepticus due to ifosfamide 显示文摘 | Kilickap S Cakar Monal IK Tufan A | 2006 | Ann Phannacother2006，40，2： | 1 |
| 8 | Clinical and radiological comparison of posterolateral fusion and posterior interbody fusion techniques for multilevel lumbar spinal stabilization in manual workers显示文摘 | Aygu n H Cakar A HO seyino?lu N | 2014 | Asian Spine J2014，8，5： | 1 |
| 9 | The effects of ator- vastatin therapy on endothelial function in patients with coronary artery disease显示文摘 | Yildiz A Cakar MA Baskurt M | 2007 | Carrdiovasc Ultrasound2007，5，： | 1 |
| 10 | Acid-base equilibria andsolubility of loratadine and desloratadine in water and micellarmedia 显示文摘 | POPOVIC G CAKAR M DANICA A | 2009 | J Pharm Biomed Anal2009，49，1： | 1 |
| 11 | Platelet-rich plasma in combination with bovine derived xenograft in the treatment of deep intrabony periodontal defects : A report of 20 consecu- tively treated patients 显示文摘 | Yilmaz S Cakar G Kuru B | 2009 | Platelets2009，20，6： | 1 |
| 12 | The protectiveness of the treatment of vitamin D insufficiency in the development of diabetes显示文摘 | Kurt O Balta S Cakar M | 2013 | Arq Bras Endocrinol Metabol2013，57，： | 1 |
| 13 | Surgical treatment of the neglected achilles tendon rupture with Hyalonect 显示文摘 | Esenyel CZ Tekin C Cakar M | 2014 | J Am Podiatr Med Assoc2014，104，5： | 1 |
| 14 | Histological evidence of decreased contralateral testicular blood flow during ipsilateral testicular torsion显示文摘 | Ciftci AO Muftuoglu S Cakar N | 1997 | Br J Uro 11997，80，5： | 1 |
| 15 | Noise elimination from measured frequency response functions显示文摘 | Sanliturk K Y Cakar O | 2005 | Mechanical Systems and Signal Processing2005，19，： | 1 |
| 16 | Improvement production of bacterial cellulose by semi-continuous process in molasses medium显示文摘 | Cakar F Ozer I Aytekin A O eta! | 2014 | Carbohydrate Polymers2014，106，1： | 1 |
| 17 | The effects of atorvastatin therapy on endothelial function in patients with coronary artery disease 显示文摘 | Ahmet Yildiz Akif Cakar Murat Baskurt | 2007 | Cardiovascular Ultrasound2007，30，5： | 1 |
| 18 | Machine number, priority rule, and due date determination in flexible manufacturing systems using artificial neural networks显示文摘 | YILDIRIM M B CAKAR T DOGUC U | 2006 | Computers & Industrial Engineering2006，50，1： | 1 |
| 19 | Acceleration of consolidation period by thrombin peptide 508 in tibial distraction osteogenesis in rats显示文摘 | Cakarer S Olgac V Aksakalli N | 2010 | Br J Oral Maxillofac Surg2010，48，8： | 1 |
| 20 | Complications associ- ated with the ball, bar and Locator attachments for im- plant-supported overdentures显示文摘 | Cakarer S Can T Yaltirik M | 2011 | Med Oral PatoI Oral Cir Bucal2011，16，7： | 1 |
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