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400篇 您的检索式：作者名="CLAYTON N"

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	题名	作者	年代	出处	被引量
1	Diagnosis in bile acid-CoA:Amino acid N-acyltransferase deficiency显示文摘Cholate-CoA ligase(CCL) and bile acid-CoA:amino acid N-acyltransferase(BAAT) sequentially mediate bile-acid amidation.Defects can cause intrahepatic cholestasis.Distinction has required gene sequencing.We assessed potential clinical utility of immunostaining of liver for CCL and BAAT.Using commercially available antibodies against BAAT and CCL,we immunostained liver from an infant with jaundice,deficiency of amidated bile acids,and transcription-terminating mutation in BAAT.CCL was normally expressed.BAAT expression was not detected.Immunostaining may facilitate diagnosis in bileacid amidation defects.	Nedim Hadzi Laura N Bull Peter T Clayton AS Knisely	2012	World Journal of Gastroenterology2012，18，25：	3
2	Increased CD3 lymphocytes and inos :further evidence of an inflammatory response in irritable bowelsyndrome显示文摘	Osullivan M Clayton N Wong T	2000	Gut2000，47，3：	2
3	基于一个大型随机试验预测稳定性心绞痛队列患者死亡、心肌梗死和卒中的危险评分显示文摘目的对需要抗心绞痛治疗并且左心室功能代偿症状稳定的心绞痛患者建立预测全因死亡、心肌梗死和导致致残性卒中的复合危险评分。设计大型多中心临床试验数据的多变量Cox回归分析。背景西欧、以色列、加拿大、澳大利亚和新西兰的心脏专科门诊患者。入选者7311例具有全部需要资料的患者被入选。主要结局的测量指标平均随访4.9年时间内所有原因的死亡、心肌梗死或者致残性卒中。结果1063例患者发生任何原因死亡或者持久性心肌梗死或者致残性卒中。这些复合终点的5年危险性在危险性最低的十分位患者为4%,而在危险性最高的十分位患者为35%。危险评分结合16项临床常规变量的降序排序是:年龄、左心室射血分数、吸烟、白细胞计数、糖尿病、随机血糖浓度、肌酐浓度、既往卒中病史、1周至少1次心绞痛发作、冠状动脉造影发现(如果能够获得)、降脂治疗、QT间期、收缩期血压≥150mmHg、抗心绞痛药物数量、陈旧性心肌梗死以及性别。把这个模型分别应用于任何原因所致的死亡、心肌梗死和卒中进行预测评估,所得的结果相似。危险评分似乎不能预测事件性质(39%的死亡、46%心肌梗死以及15%致残性卒中)或者冠状动脉造影或血管重建率(占29%的患者)。结论该危险评分对客观地决定稳定性心绞痛患者进一步治疗措施以减少重要预后事件发生是有帮助的。该危险评分同样可以用于将来的计划性试验。	Tim C Clayton Stuart J Pocock Jacobus Lubsen Zoltán Vokó Bridget-Anne Kirwan Keith A A Fox Philip A Poole-Wilson	2006	英国医学杂志中文版2006，9，1：	2
4	Oxygen isotope fractionation divalent metal carbonates显示文摘	O'Neil J R Clayton R N Mayada T K	1969	Chemistry Geophysics1969，51，：	1
5	Identification of transcrip- tional regulatory elements in human mitochondrial DNA by linker substitution analysis显示文摘	TOPPER J N CLAYTON D A	1989	Mol Cell Biol1989，9，3：	1
6	Oxygen isotope exchange between quartz and water显示文摘	Clayton Robert N	1972	Journal of geophysical research1972，77，17：	1
7	Utility of plasma N - terminal brain natriuretic peptide as a marker of functional capacity in patients with chronic severe mitral regurgitation显示文摘	Yusoff R Clayton N Keevil B	2006	Am J Cardiol2006，97，：	1
8	Expanding geriatrics into subspeciahy internal medicine healthcare, research and education :caring for older adults and the T显示文摘	High K P Clayton C P Woolard N	2002	Am J Med2002，113，6：	1
9	High temperature isotope effect in the early solar system 显示文摘	Clayton R N	1986	Reviews in Mineralogy1986，16，：	1
10	Application of geostatistics to characterize leaf area index (LAI) from flux tower to landscape scales using a cyclic sampling design显示文摘	Burrows S N Gower S T Clayton M K	2005	Ecosystems2005，5，：	1
11	Unlubricated Sliding and Rolling/ Sliding Behavior of Continuously Cooled,Low/Medium Carbon Bainitic Steels显示文摘	CLAYTON P JIN N	1996	Wear1996，200，：	1
12	Molecular genetic aspects of human mitochondrial disorders 显示文摘	Larsson N G Clayton D A	1995	Annu Rev Genet1995，29，：	1
13	Oxygen isotope exchange be- tween quartz and water 显示文摘	Clayton R N Nell JR Mayeda TK	1972	Journal of Geophysical Research1972，，77：	1
14	Oxygen isotope exchange between quartz and water 显示文摘	Clayton R N O'Neil J R Mayeda T K	1972	Journal of Geophysical Research1972，77，：	1
15	Initiation and beyond:multiple functions of the human mitochondrial transcription machinery显示文摘	Bonawitz N D Clayton D A Shadel G S		0，，06：	1
16	Increased mast cells in the irritable bowel syndrome显示文摘	O'Sullivan M Clayton N Breslin NP	2000	Neurogasttroenterol Motil2000，12，5：	1
17	Oxygen isotope exchange between quartz and water 显示文摘	Clayton R N O'Neil J R Mayeda T K	1972	Journal of Geophysical Research1972，77，：	1
18	Increased mastcells in the irritable bowel syndrome显示文摘	O'sullivan M Clayton N Breslin NP	2000	NeurogastroenterolMotil2000，12，5：	1
19	Increased mast cells in the irrilable bowel syndrome显示文摘	O'Sullivan M Clayton N Breslin NP	2000	Neurogastroenterol Motil2000，12，5：	1
20	Increased mastcells in the irritable bowel syndrome显示文摘	O'sullivan M Clayton N Breslin NP	2000	NeurogastroenterolMotil2000，12，5：	1

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