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| 1 | Using Statistical Downscaling to Quantify the GCM-Related Uncertainty in Regional Climate Change Scenarios: A Case Study of Swedish Precipitation显示文摘有在地区性的气候变化情形的不确定性的很多来源。当统计 downscaling 被用来获得地区性的气候变化情形时,不确定性可以在使用的模型,统计模型的技巧,和强迫的情形用于世界气候模型的世界气候从不确定性发源。与世界气候模型联系的不确定性能被基于一套不同世界气候模型在预言者并且在 downscaled 气候变化情形检验差别评估。什么时候标准化了象 CoupledModel Intercomparison 工程(CMIP2 ) 的第二个阶段那样的世界气候模型模拟,被使用,在 downscaled 变量的差别主要在模仿的气候在气候模型和自然可变性反映差别。Itis 建议估计的传播能作为与世界气候模型联系的不确定性的一项措施被拿。建议方法在瑞典在地区性的降水变化情形被用于评价 ofglobal-climate-model-related 不确定性。尽管在降水的变化的可观的传播存在,基于在整个瑞典的年度降水有全面增加的 17 世界气候模型表演源于统计 downscaling。一般增加能被归因于增加的 large-scaleprecipitation 和提高的偏午。估计的不确定性将近独立于区域。然而,有季节的依赖。为冬季的估计显示出信心的高水平,当为夏天的估计最不出现时。 | Deliang CHEN Christine ACHBERGER Jouni R■IS■NEN Cecilia HELLSTRM | 2006 | Advances in Atmospheric Sciences2006，23，1： | 9 |
| 2 | How location and cellular signaling combine to activate the NLRP3 inflammasome显示文摘NOD-,LRR-,and pyrin domain-containing 3(NLRP3)is a cytosolic innate immune sensor of cellular stress signals,triggered by infection and sterile inflammation.Upon detection of an activating stimulus,NLRP3 transitions from an inactive homo-oligomeric multimer into an active multimeric inflammasome,which promotes the helical oligomeric assembly of the adaptor molecule ASC.ASC oligomers provide a platform for caspase-1 activation,leading to the proteolytic cleavage and activation of proinflammatory cytokines in the IL-1 family and gasdermin D,which can induce a lytic form of cell death.Recent studies investigating both the cellular requirement for NLRP3 activation and the structure of NLRP3 have revealed the complex regulation of NLRP3 and the multiple steps involved in its activation.This review presents a perspective on the biochemical and cellular processes controlling the assembly of the NLRP3 inflammasome with particular emphasis on structural regulation and the role of organelles.We also highlight the latest research on metabolic control of this inflammatory pathway and discuss promising clinical targets for intervention. | Anil Akbal Alesja Dernst Marta Lovotti Matthew S.J.Mangan Róisín M.McManus Eicke Latz | 2022 | Cellular & Molecular Immunology2022，19，11： | 2 |
| 3 | UDP-glucuronosyltransferases: gene structures of UGT1 and UGT2 families显示文摘 | Owens IS Basu NK Banetjee R | 2005 | Methods Enzymol2005，400，： | 1 |
| 4 | Peripheral neuropathy in multiple sclerosis: a clinical and electrophysiologic study显示文摘 | Pinhas IS Achiron A Gilad R | 1995 | Acta Neurol Scand1995，91，： | 1 |
| 5 | Utility of IgE (total and Aspergillus fumigatus specific) in monitoring for response and exacerbations in allergic bronchopulmonary aspergillosis显示文摘 | Agarwal R Aggarwal AN Sehgal IS | 2016 | Mycoses2016，59，1： | 1 |
| 6 | Effects of prolonged infusion of human Alpha-1 ealeitonin gene-related pepfide on hemodynamics,renal blood flow and hormone levels in congestive heart failure显示文摘 | Shekhar YC Anand IS Sarma R | 1991 | Am J Cardiol1991，67，： | 1 |
| 7 | Direct comparison of B-type natriuretic peptide (BNP) and amino-terminal pmBNP in a large population of patients with chronic and symptomatic heart failure : the Valsartan Heart Failure (Val-HeFr) data显示文摘 | Masson S Latini R Anand IS | 2006 | Clin Chem2006，52，8： | 1 |
| 8 | Patterns of mortality and cau- ses of death in polytrauma patients-has anything changed显示文摘 | Pfeifer R Tarkin IS Rocos B | 2009 | In- jury2009，40，9： | 1 |
| 9 | Quality improvement guidelines for en-dovasculartreatment of iliacartery occlusive disease 显示文摘 | T set is D Uberoi R | 2008 | Cardiovasc Intervent Radi-ol2008，31，2： | 1 |
| 10 | Association of plasmino-gen activator inhibitor-1 and tissue plasminogen activator with type2 iabetes and metabolic syndrome in Malaysian subjects 显示文摘 | Al-Hamodi Z Ismail IS Saif-Ali R | 2011 | Cardio-vasc Diabetol2011，10，： | 1 |
| 11 | Curr:'nt status of laparoseopic partial uephrectomy显示文摘 | Fisenberg MS Brandina R Gill IS | 2010 | Curt Ofin Urol2010，20，5： | 1 |
| 12 | Dynamic contrast-enhanced MRI in endometrial carcinoma identifies patients at increased risk of recurrence显示文摘 | Haldorsen IS Grtiner R Hnsby JA | 2013 | Eur Radio12013，23，： | 1 |
| 13 | Slow growth did not decouple the otolith size-fish size relationship in striped bass 显示文摘 | DICKEY C L ISELY J J TOMASSO J R | 1997 | Transactions of the American Fisheries Society1997，126，11： | 1 |
| 14 | Expression of a single gene,BCL-6,strongly prediets survival in patients with diffuse large B-cell lymphoma显示文摘 | Lossos IS Jones CD Warnke R | 2001 | Blood2001，98，4： | 1 |
| 15 | The Potential of using vegetable oil fuels as fuel for diesel engines 显示文摘 | Altin R Cetinkaya S Yucesu H IS | 2001 | Energy Convers Manage2001，42，： | 1 |
| 16 | Carbonate cement at ion in a sequence- stratigraphic framwork: Upper Cretaceous sandstones,Book Cliffs,Utah-Colorado 显示文摘 | Taylor K G Gawthorpe R L Curt is C D | 2000 | Journal of Sedimentary Research2000，70，2： | 1 |
| 17 | Subjective memory impairment, cognitive function and depression-a community study in older Ko- reans 显示文摘 | Kim JM Stewart R Shin IS | 2003 | Dement Geriatr Vognit Disord2003，15，4： | 1 |
| 18 | GATA-4 mutations cause human congenital heart defects and reveal an interaction with TBX-5显示文摘 | Garg V Kathiriya IS Barnes R | 2005 | Nature2005，424，6947： | 1 |
| 19 | The prognostic value of big endothelin-1 in more than 2 300 patients with heart failure enrolled in the Valsartan Heart Failure Trial(Val-HEFT)显示文摘 | Masson S Latini R Anand IS | 2006 | J Card Fail2006，12，5： | 1 |
| 20 | Collaborative practice in health systems change: the Nova Scotia experience with the strengthening Primary Care Initiative 显示文摘 | Martin-Misener R McNab J Sketris IS | 2004 | Nurs keadersh ( Tor Ont)2004，17，2： | 1 |
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