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| 1 | Nonlinear optical properties of integrated GeSbS chalcogenide waveguides显示文摘In this paper, we report the experimental characterization of highly nonlinear Ge Sb S chalcogenide glass waveguides.We used a single-beam characterization protocol that accounts for the magnitude and sign of the real and imaginary parts of the third-order nonlinear susceptibility of integrated Ge23 Sb7 S70(GeSbS) chalcogenide glass waveguides in the near-infrared wavelength range at λ =1580 nm. We measured a waveguide nonlinear parameter of 7.0±0.7 W^(-1)· m(-1), which corresponds to a nonlinear refractive index of n_2=0.93±0.08 × 10^(-18) m^2∕W,comparable to that of silicon, but with an 80 times lower two-photon absorption coefficient βTPA=0.010± 0.003 cm∕GW, accompanied with linear propagation losses as low as 0.5 dB/cm. The outstanding linear and nonlinear properties of Ge Sb S, with a measured nonlinear figure of merit FOMTPA=6.0 ±1.4 at λ =1580 nm, ultimately make it one of the most promising integrated platforms for the realization of nonlinear functionalities. | SAMUEL SERNA HONGTAO LIN CARLOS ALONSO-RAMOS ANUPAMA YADAV XAVIER LE ROUX KATHLEEN RICHARDSON ERIC CASSAN NICOLAS DUBREUIL JUEJUN HU LAURENT VIVIEN | 2018 | Photonics Research2018，6，5： | 3 |
| 2 | Hybrid silicon slotted photonic crystal waveguides:how does third order nonlinear performance scale with slow light?显示文摘We investigate in this paper the influence of slow light on the balance between the Kerr and two-photon absorption(TPA) processes in silicon slotted hybrid nonlinear waveguides. Three typical silicon photonic waveguide geometries are studied to estimate the influence of the light slow-down factor on the mode field overlap with the silicon region, as well as on the complex effective nonlinear susceptibility. It is found that slotted photonic crystal modes tend to focalize in their hollow core with increasing group index(n_G) values. Considering a hybrid integration of nonlinear polymers in such slotted waveguides, a relative decrease of the TPA process by more factor of 2 is predicted from n_G=10 to n_G=50. As a whole, this work shows that the relative influence of TPA decreases for slotted waveguides operating in the slow light regime, making them a suitable platform for third-order nonlinear optics. | Junfei Xia Samuel Serna Weiwei Zhang Laurent Vivien éric Cassan | 2016 | Photonics Research2016，4，6： | 2 |
| 3 | Granulo-monocyto apheresis is more effective in mild ulcerative colitis than in moderate to severe disease显示文摘AIM:To evaluate whether the effectiveness of Granulomonocyto apheresis(GMA),a technique that consists of the extracorporeal removal of granulocytes and monocytes from the peripheral blood,might vary according to the severity of ulcerative colitis(UC)in patients with mild to moderate-severe disease UC activity.METHODS:We retrospectively reviewed prospectively collected data of patients undergoing GMA at our inflammatory bowel disease centre who had at least a 6 mo of follow-up.The demographics,clinical and laboratory data were extracted from the patients’charts and electronic records.The severity of UC was scored according to the Modified Truelove Witts Severity Index(MTWSI).A clinical response was defined as a decrease from baseline of≥2 points or a value of MTWSI≤2 points.RESULTS:A total of 41(24 males/17 females;meanage 47 years)patients were included in the study.After GMA cycle completion,21/28(75%)of mild UC patients showed a clinical response compared with 7/13(54%)of patients with moderate to severe disease(P=0.27).At 6-mo,14/28(50%)of the mild UC patients maintained a clinical response compared with 2/13(15%)of the patients with moderate to severe disease(P=0.04).After the GMA cycle completion and during the 6-mo follow up period,13/16(81%)and 9/16(56%)of mild UC patients with intolerance,resistance and contraindications to immunosuppressants and/or biologics showed a clinical response compared with 2/6(33%)and 0/6(0%)of patients with moderate to severe disease activity with these characteristics(P=0.05and P=0.04,respectively).CONCLUSION:Patients with mild UC benefit from GMA more than patients with moderate to severe disease in the short-term period.GMA should be considered a valid therapeutic option in cases of contraindications to immunosuppressants,corticosteroids and/or biologics. | Chiara De Cassan Edoardo Savarino Piero Marson Tiziana Tison Giorgia Hatem Giacomo Carlo Sturniolo Renata D'Incà | 2014 | World Journal of Gastroenterology2014，20，45： | 2 |
| 4 | Trough levels and antibodies to infliximab may not predict response to intensification of infliximab therapy in patients with inflammatory bowel disease显示文摘 | Benjamin Pariente Guillaume Pineton de Chambrun Roman Krzysiek Marine Desroches Gauthier Louis Chiara De Cassan Clotilde Baudry Jean‐Marc Gornet Pierre Desreumaux Dominique Emilie Jean‐Frédéric Colombel Matthieu Allez | 2011 | Inflamm Bowel Dis2011，，7： | 2 |
| 5 | High-performance waveguide-integrated germanium PIN photodiodes for optical communication applications[Invited]显示文摘This paper reports on high-performance waveguide-integrated germanium photodiodes for optical communications applications.200 mm wafers and production tools were used to fabricate the devices.Yields over 97%were obtained for three different compact photodiodes(10×10μm and intrinsic region width of 0.5,0.7,and 1μm)within the same batch of three wafers.Those photodiodes exhibit low dark currents under reverse bias with median values of 74,62,and 61 nA for intrinsic widths of 0.5,0.7,and 1μm,respectively,over a full wafer.Responsivities up to 0.78 A∕W at 1550 nm and zero bias were measured.Zero bias operation is possible for 25 and 40 Gbps with receiver sensitivity estimated to−13.9 and−12.3 dBm,respectively. | Léopold Virot Laurent Vivien Jean-Marc Fédéli Yann Bogumilowicz Jean-Michel Hartmann Frédéric Bœuf Paul Crozat Delphine Marris-Morini Eric Cassan | 2013 | Photonics Research2013，1，3： | 2 |
| 6 | Enhanced mid-to-near-infrared second harmonic generation in silicon plasmonic microring resonators with low pump power显示文摘We propose an efficient and low-power second harmonic generation(SHG)process in a silicon-compatible hybrid plasmonic microring resonator.By making the microring resonator doubly resonant at the fundamental wavelength of 3.1μm and second harmonic wavelength of 1.55μm,the SHG efficiency is enhanced by almost two orders of magnitude when compared to the previous result induced in a straight plasmonic waveguide.A SHG efficiency of 13.71%is predicted for a low pump power of 20 mW in a ring with radius of 2.325μm.This device provides a potential route for realizing efficient frequency conversion between mid-infrared and near-infrared wavebands on a chip. | Jihua Zhang Eric Cassan Xinliang Zhang | 2014 | Photonics Research2014，2，5： | 2 |
| 7 | 25 Gbps low-voltage hetero-structured silicongermanium waveguide pin photodetectors for monolithic on-chip nanophotonic architectures显示文摘Near-infrared germanium(Ge) photodetectors monolithically integrated on top of silicon-on-insulator substrates are universally regarded as key enablers towards chip-scale nanophotonics, with applications ranging from sensing and health monitoring to object recognition and optical communications. In this work, we report on the highdata-rate performance pin waveguide photodetectors made of a lateral hetero-structured silicon-Ge-silicon(Si-Ge-Si) junction operating under low reverse bias at 1.55 μm. The pin photodetector integration scheme considerably eases device manufacturing and is fully compatible with complementary metal-oxide-semiconductor technology. In particular, the hetero-structured Si-Ge-Si photodetectors show efficiency-bandwidth products of^9 GHz at-1 V and ~30 GHz at-3 V, with a leakage dark current as low as ~150 nA, allowing superior signal detection of high-speed data traffic. A bit-error rate of 10-9 is achieved for conventional 10 Gbps, 20 Gbps, and25 Gbps data rates, yielding optical power sensitivities of-13.85 dBm,-12.70 dBm, and-11.25 dBm, respectively. This demonstration opens up new horizons towards cost-effective Ge pin waveguide photodetectors that combine fast device operation at low voltages with standard semiconductor fabrication processes, as desired for reliable on-chip architectures in next-generation nanophotonics integrated circuits. | DANIEL BENEDIKOVIC LéOPOLD VIROT GUY AUBIN FARAH AMAR BERTRAND SZELAG BAYRAM KARAKUS JEAN-MICHEL HARTMANN CARLOS ALONSO-RAMOS XAVIER LE ROUX PAUL CROZAT ERIC CASSAN DELPHINE MARRIS-MORINI CHARLES BAUDOT FRéDéRIC BOEUF JEAN-MARC FéDéLI CHRISTOPHE KOPP LAURENT VIVIEN | 2019 | Photonics Research2019，7，4： | 2 |
| 8 | Altered anxiety-related and abnormal social behaviors in rats exposed to early life seizures显示文摘 | Castelhano AS Cassane Gdos S Scorza FA | 2013 | Front Behav Neurosci2013，7，： | 1 |
| 9 | Oil recovery efficiency and the rock-pore properties of some sandstone reservoirs显示文摘 | Wardlaw N Cassan J P | 1979 | Bulletin of Canadian Petroleum Geology1979，27，2： | 1 |
| 10 | Supercontinuum generation in silicon photonics platforms显示文摘Nonlinear optics has not stopped evolving,offering opportunities to develop novel functionalities in photonics.Supercontinuum generation,a nonlinear optical phenomenon responsible for extreme spectral broadening,attracts the interest of researchers due to its high potential in many applications,including sensing,imaging,or optical communications.In particular,with the emergence of silicon photonics,integrated supercontinuum sources in silicon platforms have seen tremendous progress during the past decades.This article aims at giving an overview of supercontinuum generation in three main silicon-compatible photonics platforms,namely,silicon,silicon germanium,and silicon nitride,as well as the essential theoretical elements to understand this fascinating phenomenon. | Christian Lafforgue Miguel Montesinos-Ballester Thi-Thuy-Duong Dinh Xavier Le Roux Eric Cassan Delphine Marris-Morini Carlos Alonso-Ramos Laurent Vivien | 2022 | Photonics Research2022，10，3： | 1 |
| 11 | Commercial applications of microalgae 显示文摘 | Spolaore P Cassan C J Duran E | 2006 | Bioscicnce and Bioengineering2006，101，2： | 1 |
| 12 | Nucleotide se-quence of the lysCgene encoding the lysine sensitiveaspartokinaseⅢof Eschench coli K12:Evolutionarypathway leading to three isofunctional enzymes显示文摘 | Cassan M Parsot C Cohen G N | 1986 | JBiol Chem1986，261，： | 1 |
| 13 | Commercialapplications of microalgae 显示文摘 | Spolaore PP Joannis -Cassan C Duran E ei al | 2006 | Journal of Bioscience andBioengineering2006，101，2： | 1 |
| 14 | Isolation and characterization of endophytic plant growth-promoting (PGPB) or stress homeostasis-regulating (PSHB) bacteria associated to the halophyte Prosopis strombulifera显示文摘 | Sgroy V Cassan F Masciarelli O | 2009 | Appl Microbiol Biotechnol2009，85，2： | 1 |
| 15 | Blood fluidity is related to the ability to oxidize lipids at exercise显示文摘 | Brun J F Varlet -Marie E Cassan D | 2004 | Clin Hemorheol Microcirc2004，30，34： | 1 |
| 16 | Large group-index bandwidth product empty core slow light photonic crystal waveguides for hybrid silicon photonics显示文摘这份报纸在绝缘体上在硅调查慢轻的繁殖宽槽 photonic 水晶波导(PCW ) 。二个设计计划被介绍,分别地依靠洞格子和槽的分散工程。模式模式和乐队图被 3D 飞机波浪扩大方法计算。然后,联合并且慢轻的繁殖在完整的 Mach-Zehnder 干涉仪(MZI ) 用有限差别时间领域方法被建模。结果显示出高振幅干扰穗和高联合效率。设备的制造和测量超过 50 与组索引导致慢轻的繁殖,当在也观察的乐队边附近的多重散布和局部性的模式时。这研究提供卓见因为在空核心槽的损失高组织索引波导。 | Charles CAER Xavier LE ROUX Samuel SERNA Weiwei ZHANG Laurent VIVIEN Eric CASSAN | 2014 | Frontiers of Optoelectronics2014，7，3： | 1 |
| 17 | Commercial applications of microalgae显示文摘 | POLAORE P S CASSAN C J DURAN E | 2006 | Bioscience and Bioengineering2006，101，2： | 1 |
| 18 | The effects of sodium chloride on ornamental shrubs 显示文摘 | Cassaniti C Leonardi C Flowers T J | 2009 | Scientia horticulturae2009，122，4： | 1 |
| 19 | Response time analysis of SiGe/Si modulation-doped multiple-quantum-well struc-tures for optical modulation显示文摘 | Marris D Cassan E Vivien L | | 0，，11： | 1 |
| 20 | UAG readthrough in mammalian cells: effect of upstream and downstream stop codon contexts reveal different signals显示文摘 | Cassan M Rousset J P | 2001 | BMC Mol Biol2001，，2： | 1 |
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