|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Exosomes:Small vesicles with big roles in cancer,vaccine development,and therapeutics显示文摘Cancer is a deadly disease that is globally and consistently one of the leading causes of mortality every year.Despite the availability of chemotherapy,radiotherapy,immunotherapy,and surgery,a cure for cancer has not been attained.Recently,exosomes have gained significant attention due to the therapeutic potential of their various components including proteins,lipids,nucleic acids,miRNAs,and lncRNAs.Exosomes constitute a set of tiny extracellular vesicles with an approximate diameter of 30-100 nm.They are released from different cells and are present in biofluids including blood,cerebrospinal fluid(CSF),and urine.They perform crucial multifaceted functions in the malignant progression of cancer via autocrine,paracrine,and endocrine communications.The ability of exosomes to carry different cargoes including drug and molecular information to recipient cells make them a novel tool for cancer therapeutics.In this review,we discuss the major components of exosomes and their role in cancer progression.We also review important literature about the potential role of exosomes as vaccines and delivery carriers in the context of cancer therapeutics. | Abhimanyu Thakur Diana Carolina Parra Pedram Motallebnejad Marcelo Brocchi Huanhuan Joyce Chen | 2022 | Bioactive Materials2022，7，4： | 8 |
| 2 | Sedation-risk-free colonoscopy for minimizing the burden of colorectal cancer screening显示文摘Unsedated colonoscopy is available worldwide,but is not a routine option in the United States(US).We conducted a literature review supplemented by our experience and expert commentaries to provide data to support the use of unsedated colonoscopy for colorectal cancer screening.Medline data from 1966 to 2009 were searched to identify relevant articles on the subject.Data were summarized and co-authors provided critiques as well as accounts of unsedated colonoscopy for screening and surveillance.Diagnostic colonoscopy was initially dev eloped as an unsedated procedure.Procedure-re lated discomfort led to wide adoption of sedation in the US,although unsedated colonoscopy remains the usual practice elsewhere.The increased use of colonoscopy for colorectal cancer screening in healthy,asymptomatic individuals suggests a reass-essment of the burden of sedation in colonoscopy for screening is appropriate in the US for lowering costs and minimizing complications for patients.A water method developed to minimize discomfort has shown promise to enhance outcomes of unsedated colonoscopy.The use of scheduled,unsedated colono scopy in the US appears to be feasible for colorectal cancer screening.Studies to assess its applicability in diverse practice settings deserve to be conducted and supported. | Felix W Leung Abdulrahman M Aljebreen Emilio Brocchi Eugene B Chang Wei-Chih Liao Takeshi Mizukami Melvin Schapiro Konstantinos Triantafyllou | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，3： | 3 |
| 3 | Characterization of Cu-Al2O3 Nano-scale Composites Synthesized by in Situ Reduction显示文摘 | Motta M S Jena P K Brocchi E A | 2001 | Materials Science and Engineering2001，15，： | 1 |
| 4 | The non-structural polyprotein 3ABC of foot-and mouth disease virus as a diagnostic antigen in ELISA to differentiate infected from vaccinated cattle显示文摘 | Diego M D Brocchi E Mackay D | 1997 | Arch Virol1997，142，： | 1 |
| 5 | The non-structural polyprotein 3ABC of foot-and-mouth disease virus as a diagnostic antigen in ELISA to differentiate infected from vaccinated cattle显示文摘 | DE DIEGO M BROCCHI E MACK AY D | 1997 | Arch Virol1997，142，10： | 1 |
| 6 | Pathogenesis of encephalomyocarditis experimental infection in young piglets:a potential animal model to study viral myocarditis显示文摘 | GELMETTI D MERONI A BROCCHI E | 2006 | Vet Res2006，37，1： | 1 |
| 7 | Development of two novel monoclonal antibody-based ELISAs for the detection of antibodies and the identification of swine isotypes against swine vesicular disease 显示文摘 | Brocchi E Berlinzani A Gamba D | 1995 | J Virol Methods1995，52，： | 1 |
| 8 | Pathogenesis of en- cephalomyocarditis experimental infection in young piglets: a po- tential animal model to study viral myocarditis 显示文摘 | Gelmetti D Meroni A Brocchi E | 2006 | Vet Res2006，37，： | 1 |
| 9 | Monoclonal antibody-based ELISA for detection of antibodies against H5 avian influenza viruses显示文摘 | Moreno A Lefli D Brocchi E | 2013 | J Virol Methods2013，187，2： | 1 |
| 10 | Pathogenesis of encephalomyocarditis experimental infection in young piglets: a potential animal model to study viral myoearditis 显示文摘 | GELMETTI D MERONI A BROCCHI E | 2006 | Vet Res2006，37，： | 1 |
| 11 | TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus 显示文摘 | Eldin P Papon L Oteiza A Brocchi E Lawson TG Mechti N | 2009 | J Gen Virol2009，90，3： | 1 |
| 12 | The occurrence of en- cephalomyocarditis virus (EMCV) in European pigs from 1990 to 2001 显示文摘 | Maurice H Nielen M Brocchi E | 2005 | Epidemiol Infect2005，133，3： | 1 |
| 13 | Development of nanostructured silver vanadates decorated with silver nanoparti- cles as a novel antibacterial agent 显示文摘 | Hohz R D Filho A G S Brocchi M | 2010 | Nanotechnology2010，21，18： | 1 |
| 14 | The nonstrucrural protein 3ABC of foot-and-mouth disease virus as a diagnostic antigen in ELISA to differentiate infected from vaccinated cattle显示文摘 | De Diego M Brocchi E Mackay D | 1997 | Arch Virol1997，142，10： | 1 |
| 15 | A further step in the evolution of rabbit hemorrhagic disease virus: the appearance of the first consistent antigenic variant显示文摘 | Lorenzo Capucci Francesca Fallacara Santina Grazioli Antonio Lavazza Maria Lodovica Pacciarini Emiliana Brocchi | 1998 | Virus Research1998，，1： | 1 |
| 16 | THE nonstructural polyprotein 3ABC of foot-and-mouth disease virus as a diagnostic antigen in ELISA to differentiate infected from vaccinated cattle显示文摘 | M De Diego A E Brocchi A D Mackay A | 1997 | Archives of Virology1997，142，10： | 1 |
| 17 | Report of the research group of the standing technical committee of the European commission for the control of FMD显示文摘 | Brocchi E Simone F Bugnetti M | 1990 | Lindholm1990，14，： | 1 |
| 18 | The non-structural polyprotein 3ABC of loot-and-mouth disease virus as a diagnostic antigen in ELISA to differentiate injected from vaccinat-ed cattle显示文摘 | Diego M D Brocchi E Mackay D | 1997 | Arch Virol1997，142，： | 1 |
| 19 | The non-structural polyprotein 3ABC of foot-and-mouth disease virus as a diagnostic antigen in ELISA to differentiate infected from vaccinated cattle显示文摘 | De Diego M Brocchi E Mackay D | | 0，，10： | 1 |
| 20 | The occurrence of encepHalomyocarditis virus (EMCV) in European pigs from 1990 to 2001 显示文摘 | Maurice H Nielen M Brocchi E etal | 2005 | Epidemiol Infect2005，133，54： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员