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| 1 | 新生儿和婴幼儿患者的连续性肾脏替代治疗:微型机器在人类的首次应用显示文摘儿童急性肾损伤(acute kidney injury,AKI)患者住院治疗越来越常见,其中几乎20%需要住监护病房。虽然AKI的长期预后目前尚无定论,但其短期内增加资源使用、住院时间和死亡风险,在需要肾脏替代治疗(renal replacement therapy,RRT)的儿童患者中尤为明显。腹膜透析是新生儿AKI患者首选的RRT疗法,但在某些情况下却是不可行或无效的。目前,常在标签外用于治疗体重小于15k婴幼儿患者的连续性RRT机器,并非为婴幼儿特别设计。最近《柳叶刀》杂志报告,意大利学者发明了一种新型微型机器,用于新生儿和婴幼儿AKI患者的RRT治疗。 | Ronco C Garzotto F Brendolan A 王建中 | 2014 | 中华肾病研究电子杂志2014，3，4： | 15 |
| 2 | Neutrophil gelatinase-associated lipocalin does not predict acute kidney injury in heart failure显示文摘BACKGROUND Acute cardiorenal syndrome type 1(CRS-1)is defined by a rapid cardiac dysfunction leading to acute kidney injury(AKI).Neutrophil gelatinaseassociated lipocalin(NGAL)is expressed on the surface of human neutrophils and epithelial cells,such as renal tubule cells,and its serum(sNGAL)and urinary have been used to predict AKI in different clinical settings.AIM To characterize CRS-1 in a cohort of patients with acute heart diseases,evaluating the potentiality of sNGAL as an early marker of CRS-1.METHODS We performed a retrospective cohort,multi-centre study.From January 2010 to December 2011,we recruited 202 adult patients admitted to the coronary intensive care unit(CICU)with a diagnosis of acute heart failure or acute coronary syndrome.We monitored the renal function to evaluate CRS-1 development and measured sNGAL levels within 24 h and after 72 h of CICU admission.RESULTS Overall,enrolled patients were hemodynamically stable with a mean arterial pressure of 92(82-107)mmHg,55/202(27.2%)of the patients developed CRS-1,but none of them required dialysis.Neither the NGAL delta value(AUC 0.40,95%CI:0.25-0.55)nor the NGAL peak(AUC 0.45,95%CI:0.36-0.54)or NGAL cutoff(≥140 ng/mL)values were statistically significant between the two groups(CRS-1 vs no-CRS1 patients).The area under the ROC curve for the prediction of CRS-1 was 0.40(95%CI:0.25-0.55)for the delta NGAL value and 0.45(95%CI:0.36-0.54)for the NGAL peak value.Finally,in multivariate analysis,the risk of developing CRS-1 was correlated with age>60 years,urea nitrogen at admission and 24 h-urine output(AUC 0.83,SE=60.5%SP=93%),while sNGAL was not significantly correlated.CONCLUSION In our population,sNGAL does not predict CRS-1,probably as a consequence of the mild renal injury and the low severity of heart disease.So,these data might suggest that patient selection should be taken into account when considering the utility of NGAL measurement as a biomarker of kidney damage. | Fiorenza Ferrari Elisa Scalzotto Pasquale Esposito Sara Samoni Flavio Mistrorigo Lilia Maria Rizo Topete Massimo De Cal Grazia Maria Virzì Valentina Corradi Rossella Torregrossa Roberto Valle Stefania Bianzina Nadia Aspromonte Matteo Floris Alessandro Fontanelli Alessandra Brendolan Claudio Ronco | 2020 | World Journal of Clinical Cases2020，8，9： | 3 |
| 3 | Impact of biofeedback- induced cardiovascular stability on hemodialysis tolerance and efficiency显示文摘 | Ronco C Brendolan A Milan M | 2000 | Kidney Int2000，58，2： | 1 |
| 4 | Pulse high - volume haemofiltration for treatment of severe sepsis: effects on hemo- dynamics and survival显示文摘 | RATANARAT R BRENDOLAN A PICCINNI P | 2005 | Crit Care2005，9，4： | 1 |
| 5 | First clinic experience with an adjunctive hemoperfusion devices design specifically to remove beta 2-microglobulins in hemodialysis显示文摘 | Ronco C Brendolan A Winchester JF Et al | 2001 | Contrib Nephrol2001，133，： | 1 |
| 6 | Pulse high - volume hemofiltration in critically Ⅲ patients: a new approach for patients with septic shock显示文摘 | RATANARAT R BRENDOLAN A RICCI Z | 2006 | Semin Dial2006，19，1： | 1 |
| 7 | Pulse high - volume haemofiltration for treatment of severe sepsis : effects on hemodynamics and survival 显示文摘 | Ratanarat R Brendolan A Piccinni P | 2005 | Crit Care2005，9，4： | 1 |
| 8 | A pilot study of coupled plasma filtration with adsorption in septic shock 显示文摘 | Ronco C Brendolan A Lonnemann G | 2002 | Crit Care Med2002，30，6： | 1 |
| 9 | Hemodiafiltration with online regeneration of the ul- trafiltrate显示文摘 | De Francisco ALM Ghezzi PM Brendolan A | 2000 | Kidney Int2000，58，： | 1 |
| 10 | Adsoption in sepsis 显示文摘 | Ronco C Brendolan A Dan M | 2000 | Kidney Int Suppl2000，76，： | 1 |
| 11 | Comparative study of longitudinal shear design criteria for composite slabs 显示文摘 | CALIXTO J M BRENDOLAN G PIMENTA R | 2009 | IBRACON Structural and Materials Journal2009，2，2： | 1 |
| 12 | Ultrafiltrationin patients with hypervolemia andcongestive heart failure 显示文摘 | Ronco C Ricci Z Brendolan A | 2004 | Blood Purif2004，22，： | 1 |
| 13 | Absorption in sepsis显示文摘 | Rpnco GL Brendolan AL Dan MA | 2000 | Kidney Interna-tional2000，76，： | 1 |
| 14 | Coupled plasma filtration absorption in the treatment of septicshock 显示文摘 | Brendolan A Bellomo R Tetta C | 2001 | Contrib Neprol2001，132，3： | 1 |
| 15 | Pulse high-volume hemofiltration in critically ill patients: a new approach for patients with septic shock显示文摘 | Ratanarat R Brendolan A Ricci Z | 2006 | Semin Dial2006，19，1： | 1 |
| 16 | Online efficiency and efficacy in relation to solute size显示文摘 | RONCO C BRENDOLAN A BELLOMO R | 1999 | Kidney Int1999，72，11： | 1 |
| 17 | Present and future options in continuous renal replacement therapies of sepsis and MOF显示文摘 | Tetta C Ronco C Brendolan A | 1999 | Minerva Anestesiol1999，65，6： | 1 |
| 18 | Pulse high volume hemofiltration显示文摘 | Brendolan A D'Intini V Ricci Z | 2004 | Int J Artif Organs2004，27，5： | 1 |
| 19 | Pulse high volume hemofiltration显示文摘 | Brendolan A Dintini V Ronco C | 2004 | Int J Art Organs2004，27，5： | 1 |
| 20 | Impact of biofeedbackinduced cardiovascular stability on hemodialysis tolerance and efficiency 显示文摘 | Ronco C Brendolan A Milan M | 2000 | Kidney Int2000，58，2： | 1 |
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