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194篇 您的检索式:作者名="Bonk"
    题名 作者 年代 出处 被引量
1Corrosion behavior of metallic alloys in molten chloride salts for thermal energy storage in concentrated solar power plants: A review显示文摘Wenjin Ding Alexander Bonk Thomas Bauer 2018Frontiers of Chemical Science and Engineering2018,12,3:14
2Reduced anoctamin 7(ANO7) expression is a strong and independent predictor of poor prognosis in prostate cancer显示文摘Objective:Anoctamin 7(ANO7)is a calcium2+-dependent chloride ion channel protein.Its expression is restricted to prostate epithelial cells.The exact function is unknown.This study aimed to analyze ANO7 expression and its clinical significance in prostate cancer(PCa).Methods:ANO7 expression was assessed by immunohistochemistry in 17,747 clinical PCa specimens.Results:ANO7 was strongly expressed in normal prostate glandular cells but often less abundant in cancer cells.ANO7 staining was interpretable in 13,594 cancer tissues and considered strong in 34.4%,moderate in 48.7%,weak in 9.3%,and negative in 7.6%.Reduced staining was tightly linked to adverse tumor features[high classical and quantitative Gleason grade,lymph node metastasis,advanced tumor stage,high Ki67 labeling index,positive surgical margin,and early biochemical recurrence(P<0.0001 each)].The univariate Cox hazard ratio for prostate-specific antigen(PSA)recurrence after prostatectomy in patients with negative vs.strong ANO7 expression was 2.98(95%confidence interval 2.61–3.38).The prognostic impact was independent of established pre-or postoperatively available parameters(P<0.0001).Analysis of annotated molecular data showed that low ANO7 expression was linked to TMPRSS2:ERG fusions(P<0.0001),elevated androgen receptor expression(P<0.0001),as well as presence of 9 of 11 chromosomal deletions(P<0.05 each).A particularly strong association of low ANO7 expression with phosphatase and tensin homolog(PTEN)deletion may indicate a functional relationship with the PTEN/AKT pathway.Conclusions:These data identify reduced ANO7 protein expression as a strong and independent predictor of poor prognosis in PCa.ANO7 measurement,either alone or in combination,might provide clinically useful prognostic information in PCa.Andreas Marx Lena Koopmann Doris Hoflmayer Franziska Büscheck Claudia Hube-Magg Stefan Steurer Till Eichenauer Till S.Clauditz Waldemar Wilczak Ronald Simon Guido Sauter Jakob R.Izbicki Hartwig Huland Hans Heinzer Markus Graefen Alexander Haese Thorsten Schlomm Christian Bernreuther Patrick Lebok Sarah Bonk 2021Cancer Biology & Medicine2021,18,1:3
3Modulation of soluble receptor or advanced glycation end products by Angiotensin - converting enzyme- 1 inhibition in diabetic nephropathy显示文摘Forbes JM Thorpe SR Thallas- Bonke V 2005J Am Soc Nephrol2005,16,8:1
4The multidimensional fatigue inventory(MFI) psychometric qualities of an instrument to assess fatigue显示文摘Smets E M Garssen B Bonke B 1995J Psychosom Res1995,39,3:1
5Visualizing metabolic changes in breast-cancer tissue using ^1H-NMR spectroscopy and self-organizing maps 显示文摘Beckonert O Monnerjahn J Bonk U 2003NMR Biomed2003,16,1:1
6A many-facet Rasch analysis of the second language group oral discussion task 显示文摘Bonk J & Ockey G 2003Lan- guage Testing2003,20,1:1
7Anesthesiology:a survey of anaesthesiological practice显示文摘Mcennan N Bonk B Oosting J 1993Anesthesiology1993,79,3:1
8Computed tomographic scanning without oral contrast solution for blunt bowel and mesenteric injuries in abdominal trauma显示文摘Allen T L Mueller M T Bonk R T 2004J Trauma2004,56,2:1
9Demonstration of an SOA-assisted open metro-access infrastructure for heterogeneous services显示文摘Schmuck H Bonk R Poehlmann W 2014Optics Express2014,22,1:1
10Synthesis and characterization of chlorinated alkenylcobaloximes to probe the mechanism of vitamin B12-catalyzed dechlorination of priority pollutants显示文摘McCauley K M Wilson S R van der Bonk W A 2002Inorg Chem2002,41,:1
11Modulation of soluble receptor for advanced glycation end products by angiotensin - converting enzyme - 1 inhibition in diabetic nephropathy 显示文摘FORBES J M THORPE S R THALLAS - BONKE V 2005J Am Soc Nephro12005,16,8:1
12Postoperative cognitive dysfunction in the elderly显示文摘Bonke B 1998Lancet1998,351,9119:1
13Assessment of preope-rative anxiety:comparison of measures in patients awaiting surgery for breast cancer显示文摘Millar K Jelicic M Bonke B 1995Br J Anaesth1995,74,2:1
14Increasing incidence of Mycobacterlum xenopi at Bellevue hospital: an emerging pathogen or a product of improved laboratory methods显示文摘Donnabella V Salazas SJ Bonk S 2000Chest2000,118,5:1
15Assessment of preoperative anxiety : comparison of measures in patients awaiting surgery for breast cancer显示文摘Millar K Jelieic M Bonke B 1995Br J Anaesth1995,74,2:1
16The Multidimensional Fatigue Inventory ( MFI ) psychometric qualities of an instrument to assess fatigue 显示文摘Smets E M Garssen B Bonke B 1995J Psychosom Res1995,39,3:1
17The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue 显示文摘SMETS E M GARSSEN B BONKE B 1995J Psychosom Res1995,39,3:1
18The Multidimensional Fa- tigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue显示文摘Smets EM Garssen B Bonke B 1995J Psychosom Res1995,39,3:1
19Circus movement in rabbit atrial muscle as a mechanism of tachycardia显示文摘Allessie MA Bonke FI Schopman FJ 1997Circ Res1997,41,:1
20Vulnerability of rabbit atrium to reentry by hypoxia:role of inhomogeneity in conduction and wavelength显示文摘Lammers WJ Kirchhof C Bonke F 1992Circulation1992,262,:1
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