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| 1 | Concurrent use of aromatase inhibitors and hypofractionated radiation therapy显示文摘AIM: To retrospectively assess the acute and long-term toxicity using aromatase inhibitors (AI) therapy concurrently with hypofractionated radiotherapy (HFRT) in breast cancer patients. METHODS: From November 1999 to October 2007, 66 patients were treated with breast HFRT and concurrent AI. In 63 patients (95.5%), HFRT delivered a total dose of 32.5 Gy to the whole breast within 5 wk (five fractions, one fraction per week). Other fractionations were chosen in three patients for the patients' personal convenience. A subsequent boost to the tumor bed was delivered in 35 patients (53.0%). Acute toxicities were scored according to the Common Toxicity Criteria for Adverse Events v3. Late toxicity was defined as any toxicity occurring more than 6 mo after completion of HFRT and was scored according to the Late Effects Normal Tissue Task Force-Subjective, Objective, Management and Analytic scale. RESULTS: At the end of the HFRT course, 19 patients (28.8%) had no irradiation-related toxicity. Acute grade 1-2 epithelitis was observed in 46 patients (69.7%). One grade 3 toxicity (1.5%) was observed. With a median follow-up of 34 mo (range: 12-94 mo), 31 patients (47%) had no toxicity, and 35 patients (53%) presented with grade 1-2 fibrosis. No grade 3 or greater delayed toxicity was observed. CONCLUSION: We found that AI was well tolerated when given concurrently with HFRT. All toxicities were mild to moderate, and no treatment disruption was necessary. Further prospective assessment is warranted. | Cyrus Chargari Pablo Castro-Pena Ivan Toledano Marc A Bollet Alexia Savignoni Paul Cottu Fatima Laki Franois Campana Patricia De Cremoux Alain Fourquet Youlia M Kirova | 2012 | World Journal of Radiology2012，4，7： | 2 |
| 2 | A cluster of ca- ses of infections due to Aerornonas hydrophila re- vealed by combined RAPD and ERIC-PCR 显示文摘 | Davin R A Bollet C Chamorey E | 1998 | Mol Epidemiol1998，47，1： | 1 |
| 3 | Postoperative brachytherapy alone and combined postoperative radiotherapy and brachytherapy boost for squamous cell carcinoma of the oral cavity, with positive or close margings 显示文摘 | Lapeyre M Bollet MA Racadot S | 2004 | Head Neck2004，26，3： | 1 |
| 4 | Pressure pulsation in centrifugal pumps显示文摘 | Guelich J F Bolleter U | 1992 | ASME Journal of Vibration and Acoustics1992，114，2： | 1 |
| 5 | Targeting poly(ADP-ribose) polymerase activity for cancer therapy显示文摘 | Megnin-Chanet F Bollet M A Hall J | 2010 | Cell Mol Life Sci2010，67，21： | 1 |
| 6 | mar operon involvedin multidrug resistance of Enterobacter aero genes显示文摘 | Chollet R Bollet C Chevalier J | 2002 | Antimicrob Agents Chemother2002，46，4： | 1 |
| 7 | Cardiac toxicity in breast cancer patients: t:om a fractional point of view to a global assessment 显示文摘 | Chargari C Kirov KM Bollet MA | 2011 | Cancer Treat Rev2011，37，4： | 1 |
| 8 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates 显示文摘 | Drancourt M Bollet C Carlioz A | 2000 | J Clin Microbiol2000，38，10： | 1 |
| 9 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates 显示文摘 | Dranourt M Bollet C Carlioz R | 2000 | Clin Microbiol2000，38，： | 1 |
| 10 | Pathological response to preoperative concurrent chemo-radiotherapy for breast cancer:Results of a phase Ⅱ study显示文摘 | Bollet M A Sigal-Zafrani B Gambotti L | 2006 | Eur J Cancer2006，42，14： | 1 |
| 11 | Polarization colors of nitrocellulose 显示文摘 | Kohlbeck J Bolleter W | 1976 | Journal of Applied Polymer Science1976，20，1： | 1 |
| 12 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates 显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | J Clin Microbiol2000，38，10： | 1 |
| 13 | Radiotherapy treatment planning of prostate cancer using magnetic resonance imaging alone显示文摘 | Lee YK Bollet M Charles-Edwards G | 2003 | Radiother Oncol2003，66，2： | 1 |
| 14 | Efficient discrimination of Mycobacterium tuberculosis strains by 16S-23S spacer region based random amplified polymorphic DNA analysis显示文摘 | Abed Y Davin-Regli A Bollet C | 1995 | J Clin Microbiol1995，31，： | 1 |
| 15 | 16SribosomalDNA sequence analysis of a large collection environ-mental and clinical unidentifiable bacterial isolates显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | Clin Microbiol2000，38，： | 1 |
| 16 | Use of random amplified polymorphic DNA for epidemiological typing of Strenotrophomonas maltophilia显示文摘 | Davin-Regi A Bollet C Auffray JP | 1996 | J Hosp Infect1996，32，1： | 1 |
| 17 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | J Clin Microbiol2000，38，： | 1 |
| 18 | Age remains the first prognostic factor for loco-regional recurrence in young women treated with breast conserving surgery first显示文摘 | Bollet MA Sigal-Zafrani B Mazeau V | 2007 | Radiother Oncol2007，82，： | 1 |
| 19 | Blade passage tones of centrifugal pumps显示文摘 | BOLLETER U | 1988 | Vibrations1988，4，3： | 1 |
| 20 | Radiotherapy treatment planning of prostate cancer using magnetic resonance imaging alone显示文摘 | Lee YK Bollet M Edwards GH | 2003 | Radiother Oncol2003，669，2： | 1 |
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