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63篇 您的检索式:作者名="Bocan"
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1Th17 cells were recruited and accumulated in the cerebrospinal fluid and correlated with the poor prognosis of anti-NMDAR encephalitis显示文摘Anti-N-methyI-D-aspartate-receptor (NMDAR)encephalitis is an autoimmune disorder characterized by memory deficits,psychiatric symptoms,and autonomic instability.The lack of suitable biomarkers targeting anti-NMDAR encephalitis makes the immunotherapy and prognosis challenging.In this study,we found that the Th17 cells were significantly accumulated in the cerebrospinal fluid (CSF)of anti-NMDAR encephalitis patients than that of control individuals.The concentration of the cytokines and chemokines including interleukin (IL)-1β,IL-17,IL-6,and CXCL-13 were significantly increased in the CSF of anti-NMDAR encephalitis patients.IL-6 and IL-17 were found to promote the differentiation of CD4+T cells into Th17 lineage.The chemotaxis assay showed that CCL20 and CCL22 play essential roles in the migration of Th17 cells.Notably,the correlation between the expression of IL-17 and the outcome of anti-NMDAR encephalitis patients was analyzed.The data showed that high level of IL-17 was significantly correlated with the limited response to the treatment and relapse of anti-NMDAR encephalitis patients.Our results suggested the potential important involvement of IL-17 in anti-NMDAR encephalitis.Chaosheng Zeng Lin Chen Bocan Chen Yi Cai Pengxiang Li Limin Yan Dehua Zeng 2018Acta Biochimica et Biophysica Sinica2018,50,12:5
2A specific 15-1ipoxygenase inhibitor limits the progres- sion and monocyte-macrophage enrichment of hyper- cholesterolemia-Induced atherosclerosis in the rabbit 显示文摘Bocan T M A Rosebury W S Mueller S B 1998Atherosclerosis1998,13,:1
3Characterization of the promoter of human extracellular matrix metalloproteinase inducer ( EMMPRIN) 显示文摘Liang L Major T Bocan T 2002Gene2002,282,122:1
4MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACEI and MMP-inhibition显示文摘LiH Simon H Bocan TMA 2000Cardiovasc Res2000,46,2:1
5The ACAT inhibitor avasimibe reduce macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits 显示文摘Bocan TM Krause BR Rosebury WS 2000Arterioscler Thromb Vase Biol2000,20,1:1
6MMP/TIMP expression in spontaneously hypertensive heart failure rats:the effect of ACE-and MMP-inhibition显示文摘Li H Simon H Bocan TM 2000Cardiovasc Res2000,46,2:1
7Pleiotropic effects of HMG-CoA reductase inhibitors显示文摘BOCAN TM 2002Curt Opin Investig Drugs2002,3,9:1
8MMP/TIMP expression in spontaneously hypertensive heart failure rats:the effect of ACE-and MMP-inhibition显示文摘Li H Simon H Bocan TM 2000Cardiovasc Res2000,46,2:1
9The ACAT inhibitor avasimibe reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits显示文摘Bocan TM Krause BR Rosebury WS 2000Arterioscler Thromb Vasc Biol2000,20,1:1
10MMP/TIMP expression in spontaneously hypertensive heart failure rats:the effect of ACE-and MMP-inhibition显示文摘Li H Simon H Bocan TM 2000Cardiovasc Res2000,46,2:1
11MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE-and MMP-inhibition显示文摘Li H Simon H Bocan TM 2000Cardiovasc Res2000,46,2:1
12The ACAT inhibitor avasimibe reduces macrophage and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits 显示文摘Bocan TM Krause BR Rosebury WS 2000Arterioscler Thromb Vasc Biol2000,20,1:1
13Hepatic and nonhepatic sterol synthesis and tissue distribution following administration of a liver selec- tive HMG-CoA reductase inhibitor 显示文摘BOCAN T M A FERGUSON E McNALLY W 1992Biochim Bio- phys Acta1992,1123,2:1
14Extracellular matrix metallproteinase inducer (EMMPRIN) is induced upon monocyte differentiation and is expressed in human atheroma显示文摘Major TC Liang L Lu X Rosebury W Bocan TM 2002Arterioscler Thromb Vasc Biol2002,22,7:1
15MMP/TIMP expression in spontaneously hypertensive heart failure rats:the effect of ACEI and MMP-inhibition显示文摘Li H Simon H Bocan TM 2000Cardiovasc Res2000,46,:1
16The ACAT inhibitor avasimibe reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits显示文摘BOCAN T M KRAUSE B R ROSEBURY W S 2000Arterioscler Thromb Vasc Biol2000,20,1:1
17MM PoT IMP expression in spontaneously hypertensive heart failure rats:the effect of ACE- and MMP-inhibition显示文摘Li H Simon H Bocan TM 2000Cardiovasc Res2000,46,2:1
18Characterization of the promoter of human extraeenular matrix metalloproteinase inducer ( EMMPRIN ) 显示文摘Liang L Major T Bocan T 2002Gene2002,282,12:1
19Characterization of the promoter of human extracellular matrix metalloproteinase inducer (EMMPRIN)显示文摘Liang L Major T Bocan T 2002Gene2002,282,12:1
20MMP/TIMP expression in spontaneously hypertensive heart failure rots: the effect of ACE-and MMP-inhibition显示文摘LI H SIMON H BOCAN TM 2000Cardiovasc Res2000,46,:1
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