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| 1 | Targeted therapy in advanced metastatic colorectal cancer: Current concepts and perspectives显示文摘The introduction of new cytotoxic substances as well as agents that target vascular endothelial growth factor(VEGF)and epidermal growth factor receptor(EGFR)signaling has improved clinical outcome of patients withmetastatic colorectal cancer(mCRC).In this review we summarize the most relevant clinical data on VEGF and EGFR targeting regimens in mCRC.The effects of available treatment strategies for mCRC are often temporary,with resistance and disease progression developing in most patients.Thus,new treatment strategies are urgently needed.Some GI peptides including gastrin and gastrin releasing peptide,certain growth factors such as insulin-like growth factor-ⅠandⅡand neuropeptides such as growth hormone releasing hormone(GHRH)are implicated in the growth of CRC.Experimental investigations in CRC with antagonistic analogs of bombesin/gastrin-releasing peptide,GHRH,and with cytotoxic peptides that can be targeted to peptide receptors on tumors,are summarized in the second part of the review. | Florian Hohla Thomas Winder Richard Greil Ferenc G Rick Norman L Block rew V Schally | 2014 | World Journal of Gastroenterology2014，20，20： | 3 |
| 2 | Re-evaluation of risks associated with hyperphosphatemia and hyperparathyroidism in dialysis patients:recommendations for a change in management显示文摘 | Block G A Port F K | | 0，，： | 2 |
| 3 | Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients:a national study显示文摘 | Block G A Hulbert-Shearon T E Levin N W | | 0，，： | 2 |
| 4 | Phytoestrogen content of foods-a compendium of literature values显示文摘 | Block G | 1996 | Nutr Cancer1996，26，2： | 1 |
| 5 | Fruit,vegetable,and cancer prevention:a review of epidemiological evidence显示文摘 | Block G Patterson B Subar A | 1992 | Nutr Cancer1992，18，： | 1 |
| 6 | Relations of glycemic index and glycemic load with plasma oxidative stress markers显示文摘 | Hu Y Block G Norkus EP | 2006 | Am J Clin Nutr2006，84，： | 1 |
| 7 | Reverse epidemiology of cardiovascular risk factors in manintenance dialysis patients显示文摘 | Kalantar-zadeh K Block G Humphreys MH | 2003 | Kidney int2003，63，3： | 1 |
| 8 | Diet and lifestyle factors associated with premenstrual symptoms in a racially diverse community sample: Study of women's health across the nation (SWAN)显示文摘 | Gold EB Bair Y Block G | 2007 | J Womens Health (Larchmt)2007，16，5： | 1 |
| 9 | Reverse epidemiology of cardiovascular risk factor in maintenance dialysis patients显示文摘 | Kalant A Zadeh K Block G | 2003 | Kidney Int2003，63，3： | 1 |
| 10 | Comparison of immediate release and controlled release carbidopa-levodopa in Parkinson's disease:A multicentre 5-year study显示文摘 | Block G Liss C Reine S | 1997 | Eur Neurol1997，37，： | 1 |
| 11 | Calcium phosphate metabolism and cardiovascular disease in patients with chronic kidney disease 显示文摘 | Block G Port FK | 2003 | Semin Dial2003，16，： | 1 |
| 12 | Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients 显示文摘 | Kalantar- Zadeh K Block G Humphreys MH | 2003 | Kidney Int2003，63，3： | 1 |
| 13 | Fruit, vegetables, and cancer prevention : a review of the epidemiological evidence 显示文摘 | Block G Patterson B Subar A | 1992 | Nutr Cancer1992，18，3： | 1 |
| 14 | A malnutrition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients显示文摘 | KALANTAR ZADEH K KOPPLE J D BLOCK G | 2001 | Am J Kidney Dis2001，38，6： | 1 |
| 15 | Mineral metabolism,mortality,and morbidity in maintenance hemodialysis显示文摘 | Block G A Klassen P S Lazarus J M | | 0，，08： | 1 |
| 16 | The data support role for antioxidants in reducing cancer risk显示文摘 | Block G | 1992 | Nutr Rev1992，50，： | 1 |
| 17 | Transcatheter closure of ventricular septal defects显示文摘 | LOCK J E BLOCK P C MCKAY R G | 1988 | Circulation1988，78，： | 1 |
| 18 | Appetite and inflammation,nutrition,anemia,and clinical outcome in hemodialysis patients显示文摘 | Kalantar ZK Block G J McAllister C | 2004 | Am J Clinical Nutrition2004，80，8： | 1 |
| 19 | Mortality after emergent percutaneous coro- nary intervention in cardiogenic shock secondary to acute myo- cardial infarction and usefulness of a mortality prediction model 显示文摘 | Klein L W Shaw R E Krone R J Brindis R G Anderson H V Block P C | 2005 | Am J Cardiol2005，96，： | 1 |
| 20 | Validation of a Food Fre- quency Questionnaire for Hispanics 显示文摘 | Block G Wakimoto P Jensen C et at | 2006 | Prey Chronic Dis2006，3，3： | 1 |
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