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| 1 | Innate immune signaling and regulation in cancer immunotherapy显示文摘先存在的 T 煽动房间的肿瘤微型环境有预示的用途并且能也为对当代的癌症免疫疗法的反应预兆。对联系肿瘤的抗原的自发的 T 房间回答的产生取决于天生的有免疫力的激活,运动打它我干扰素(IFN ) 生产。最近的工作为在这个过程察觉到的 cytosolic DNA 的 STING 小径揭示了一个主要角色。事件的这串联贡献 Batf3 系树枝状的房间(DC ) 的激活,它看起来对反肿瘤免疫中央。Non-T 煽动房间的肿瘤为 Batf3 DC 招募缺乏 chemokines,有很少 Batf3 DC,并且缺乏一种类型我 IFN 基因签名,建议那没有通过天生的有免疫力的激活可以是因缺乏自发的 T 房间激活和累积的最终的原因。与手里的这个信息,为触发天生的有免疫力的激活和 Batf3 DC 招募的新策略正在被开发,包括为 de novo 免疫者 priming 的新奇圈套收缩筋。最终,有效天生的有免疫力的使活跃之物的成功的发展应该扩展能对免疫疗法作出回应的病人的部分,例如与检查点封锁抗体。 | Leticia Corrales Vyara Matson Blake Flood Stefani Spranger Thomas F Gajewski | 2017 | Cell Research2017，27，1： | 13 |
| 2 | Vascular closure devices and the risk of vascular complications after percutaneous coronary intervention in patients receiving glycoprotein IIb-IIIa inhibitors显示文摘 | RESNIC F S BLAKE G J OHNO-MACHADO L | 2001 | Am J Cardiol2001，88，5： | 2 |
| 3 | Phase Ⅱ trial of pemetrexed (P) and gemcitabine (G) as first-line chemotherapy for elderly and/or poor performance status patients with stage ⅢB/IV non-small cell lung cancer (NSCLC)显示文摘 | Blakely J Schnell F Kaywin P | 2006 | J Clin Oncol2006，24，18： | 1 |
| 4 | Interstitial water and sediment chemistries of Lake Aiguebelette (Savoy, France) 显示文摘 | Gaillard J F Sarazin G Pauwels H Philippe L Lavergne D Blake G | 1987 | Chem Geol1987，63，12： | 1 |
| 5 | Spherical wave propagation in solid media显示文摘 | Blake F G | 1952 | The Journal of the Acoustical Society of America1952，24，2： | 1 |
| 6 | A report of the successful surgical treatment of aortic regurgitation from a disseeting aortic aneurysm in a patient with the Marfan syndrome显示文摘 | Spencer F C Blake H | 1962 | J Thorac Cardiovasc Surg1962，44，： | 1 |
| 7 | Early-response enhancements for mass-casualty radiologieal incidents and terrorism 显示文摘 | BLAKELY W F SALTER C A biological dosimetry-reeommended PRASANNA P G | 2005 | Health Phys2005，89，5： | 1 |
| 8 | Graphene-based liquid crystal device 显示文摘 | BLAKE P BRIMICOMBE P D NAIR R R BOOTH T J JIANG D SCHEDIN F PONOMARENKO L A MOROZOV S V GLEESON H F HILL E W GEIM A K NOVOSELOV K S | 2008 | Nano Letters2008，8，6： | 1 |
| 9 | Efficient Algorithms for Koblitz Curves over Fields of Characteristic Three显示文摘 | Blake I F Kumar M V Xu Guangwu | 2005 | Journal of Discrete Algorithms2005，3，1： | 1 |
| 10 | Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin显示文摘 | Neilan TG Blake SL Ichinose F | 2007 | Circulation2007，116，5： | 1 |
| 11 | Radiation exposure assessment using cytological and molecular biomarkers 显示文摘 | Blakely W F Prasarma P G Grace M B | 2001 | Radiat Prot Dosimetry2001，97，1： | 1 |
| 12 | Codes over integer residue rings显示文摘 | Blake I F | 1975 | Information and Control1975，29，4： | 1 |
| 13 | Neural bases of binocular rivalry显示文摘 | Tong F Meng M Blake R | 2006 | Trends Cogn Sci2006，10，11： | 1 |
| 14 | Microseismic techniques for monitoring the behavior of rock structures显示文摘 | BLAKE W LEIGHTON F DUVALL W I | 1975 | International Journal of Rock Mechanics and Mining Sciences and Geomechanics Abstracts1975，12，4： | 1 |
| 15 | The development of a clinician - administered PTSD scale 显示文摘 | Blake D D Weathers F W Nagy L M | 1995 | Journal of Traumatic Stress1995，8，： | 1 |
| 16 | Ductility Capacity Models for Buckling-Restrained Braces显示文摘 | Blake M A Larry A F Song J H | 2009 | Journal of Constructional Steel Research2009，，65： | 1 |
| 17 | Enzyme immunoassay to determine heavy metals using antibodies to specific metal-EDTA complexes:optimization and validation of an immunoassay for soluble indium显示文摘 | CHAKRABARTI M HATCHER F M BLAKE R C | 1994 | Analytical Chemistry1994，217，： | 1 |
| 18 | Real-time quantitative RT-PCR assay of GADD45 gene expression changes as a biomarker for radiation biodosimetry显示文摘 | Grace M B Mcleland C B Blakely W F | 2002 | Int J Radiat Biol2002，7，11： | 1 |
| 19 | Continuing Worldwide Increase in Tropospheric Methane,1978 to 1987 显示文摘 | BLAKE D ROWLAND F | 1988 | Sclence1988，239，4844： | 1 |
| 20 | Emission characteristicsof CO,NOx,SO2 and indications of biomass burning observed at arural site in eastern China显示文摘 | WANG Tao CHEUNG T F BLAKE D R | 2002 | Journal of Geophysical Research:Atmospheres2002，107，12： | 1 |
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