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| 1 | Concurrent stenoses: A common etiology of stroke in Asians显示文摘Atherosclerosis of cerebral vessels is a common cause of stroke. Racial differences in the distribution of cerebrovascular occlusive disease are well documented.Extracranial stenosis is more common in Caucasians,while intracranial stenosis is more common in Asians,Hispanics and African-Americans. Concurrent atherosclerosis of extracranial and intracranial vessels is common in Asians. The incidence of concurrent stenoses ranges from 10% to 48% in patients with symptomatic cerebrovascular disease. The long-term prognosis of these patients is poor and they are at high risk of further vascular events or death. The purpose of this review is to examine the epidemiology, risk factors,stroke mechanism and genetics of concurrent stenoses and to discuss strategies for treatment. | Bik Ling Man Yat Pang Fu | 2014 | World Journal of Clinical Cases2014，2，6： | 8 |
| 2 | Chinese topical herbal medicine gives additive effect on pharmaceutical agent on fracture healing显示文摘OBJECTIVE:To investigate the efficacy on the combination of oral strontium ranelate(Sr R)with a topical Chinese herbal paste on facilitation of fracture healing.METHODS:An open fracture was created at the mid-shaft of the right tibia of rat.A herbal pastecalled CDR containing Honghua(Flos Carthami),Chuanxuduan(Radix Dipsaci Asperoidis)and Dahuang(Radix Et Rhizoma Rhei Palmati)was prepared.The rats were treated with either CDR topically on the fracture site,or Sr R orally,or their combinations.Bone turnover biochemical markers in serum were measured.Microarchitecture of the fracture was analyzed using micro-CT after 14 and 28 d,followed by histomorphometrical analysis.RESULTS:Micro-computed tomography analysis revealed that the combined treatment of CDR with600 mg/g Sr R significantly increased the total callus density,mineralized callus volume fraction,mineralized callus mineral content and mineralized callus density of the callus after 28 d of treatment.This result was consistent with the histomorphometrical analysis on the osteoid volume.Analysis of biochemical markers showed that the combined treatments reduced the bone resorption that occurs temporarily after fracture.CONCLUSION:This study demonstrated that the combined treatment of oral Sr R and topical CDR is effective to promote fracture healing by their additive effect on promoting bone formation and retarding bone resorption. | Siu Wing Sum Shiu Hoi Ting Shum Wai Ting Ko Chun Hay Lau Clara Bik San Hung Leung Kim Leung Ping Chung | 2019 | Journal of Traditional Chinese Medicine2019，39，6： | 4 |
| 3 | Management of an outbreak of Enterobacter cloacae in a neonatal unit using simple preventive measures显示文摘 | Dijk YV Bik EM Hochstenbach-Vernooij S | 2002 | Hosp Infect2002，51，1： | 1 |
| 4 | Diversity of the human intestinal microbial flora 显示文摘 | Eckburg P B Bik E M Bernstein C N | 2005 | Science2005，308，： | 1 |
| 5 | Molecular analysis of the bcterialmcorbiota in the human stomach显示文摘 | Bik EM Eckburg PB Gill SR | 2006 | Proc NatAcad Sci USA2006，10，： | 1 |
| 6 | Diversity of the human intestinal microbial flora显示文摘 | Bik E M Bernstein C N | 2005 | Science2005，308，： | 1 |
| 7 | Diversity of the human intestinal microbial flora显示文摘 | Eckburg PB Bik EM Bernstein CN | 2005 | Science2005，308，5728： | 1 |
| 8 | Development of the human infant intestinal microbiota显示文摘 | Palmer C Bik E M DiGiulio D B et at | 2007 | PLoS Biol2007，5，： | 1 |
| 9 | Diversity of the human in- testinal microbial flora显示文摘 | Eckburg PB1 Bik EM Bemstein CN | 2005 | Science2005，308，5728： | 1 |
| 10 | Insertion element IS987 from Mycobacterium boris BCG is located in a hot-spot in- tegration region for insertion elements in Mycobacterium tuber-culosis complex strains显示文摘 | Hermans P Van Soolingen D Bik E | 1991 | Infect immun1991，59，8： | 1 |
| 11 | Diversity of the human intestinal microbial flora显示文摘 | Eckburg PB Bik EM Bernstein CN | 2005 | Science2005，308，5728： | 1 |
| 12 | The role of leptin and orexins in the dysfunction of hypothalamo-pituitary-gonadal regulation and in the mechanism of hypera-ctivity in patients with anorexia nervosa显示文摘 | Baranowska B Baranowska-Bik A Bik W | 2008 | Neuro Endocrinol Lett2008，29，1： | 1 |
| 13 | Development of the human infant intestinal microbiota显示文摘 | Palmer C Bik E M DiGiulio D B | 2007 | PLoS Biol2007，5，： | 1 |
| 14 | Diversity of the human intestinal microbial flora 显示文摘 | Eekburg PB Bik EM Bernstein CN | 2005 | Science2005，308，5728： | 1 |
| 15 | Vasoactive intestinal peptide (VIP) and pituitary adenylate cycla- se activating polypeptide (PACAP) in humans with multiple scle- rosis显示文摘 | BARANOWSKA BIK A KOCHANOWSKI J UCHMAN D | 2013 | J Neuroimmunol2013，263，12： | 1 |
| 16 | Resistin levels in women with ischemic stroke 显示文摘 | Kochanowski J Grudniak M Baranowska - Bik A | 2012 | Neuro Endocrinol Lett2012，33，6： | 1 |
| 17 | Bacterial diversity in the oral cavity of 10 healthy individuals显示文摘 | Bik EM Long CD Armitage GC | 2010 | ISME J2010，4，8： | 1 |
| 18 | Anti-DNA au-toantibodies stimulate the release of interleukin-1 and interleukin -6 from endothelial cells显示文摘 | NENGLAIK LEUNGJ C BIK LAI K | 1996 | J Pathol1996，178，4： | 1 |
| 19 | Development of the human infant intestinal microbiota显示文摘 | Palmer C Bik EM DiGiulio DB | 2007 | PLoS Biol2007，5，7： | 1 |
| 20 | PACAP38 as a modulator of immune and endocrine responses during LPS-induced acute inflammation in rats 显示文摘 | Bik W Wolinska-Witort E Pawlak J | 2006 | J Neuroimmunol2006，177，12： | 1 |
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