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| 1 | Utility of magnetic resonance imaging in anorectal disease显示文摘Imaging of both benign and malignant anorectal diseases has traditionally posed a challenge to clinicians, and as a result history and physical exam have been relied on heavily. CT scanning and endorectal ultrasound have become popular in assessment of anatomy and staging of tumors, but have limitations. Magnetic resonance imaging (MRI) has the capability to fill in the gaps left open by more conventional imaging modalities and continues to be promising as the definitive imaging technique in the pelvis, especially with advancement of emerging technologies in this field. A comprehensive review of this topic has been undertaken. Anorectal disease is divided into three broad categories: cancer, fistula/abscess, and pelvic floor disorders. A review of the literature is performed to evaluate the use of MRI and other imaging modalities in these three areas. Preoperative imaging is useful in the evaluation of all three areas of anorectal disease. MRI is an effective tool in delineating anatomy and, when correlating with the specific clinical scenario, is an effective adjunct in clinical decision-making in order to optimize outcome. MRI continues to be a promising and novel approach to imaging various afflictions of the anorectum and the pelvic floor. Its role is more well-established in some areas than in others, and there are still signif icant limitations. As technology advances, MRI will shed more light on a complex anatomical area. | Loren Berman Gary M Israel Shirley M McCarthy Jeffrey C Weinreb Walter E Longo | 2007 | World Journal of Gastroenterology2007，13，23： | 11 |
| 2 | Key factors in developing the trinitrobenzene sulfonic acid-induced post-inflammatory irritable bowel syndrome model in rats显示文摘AIM:To investigate the key factors in developing the trinitrobenzene sulfonic acid(TNBS)-induced postinflammatory irritable bowel syndrome(PI-IBS)model in rats. METHODS:TNBS was administered to rats at the following conditions:(1)with different doses(20,10,5 mg/0.8 mL per rat);(2)with same dose in different concentrations(20 mg/rat,25,50 mg/mL);(3)in different ethanol percentage(25%,50%);and(4)at depth either 4 cm or 8 cm from anus.At 5 d and 4 wk after TNBS administration,inflammation severity and inflammation resolution were evaluated.At 4 and 8 wk after TNBS application,visceral hyperalgesia and enterochromaffin(EC)cell hyperplasia were assayed by abdominal withdrawal reflex test,silver staining and capillary electrophoresis. RESULTS:Our results showed that:(1)TNBS induced dose-dependent acute inflammation and inflammation resolution.At 5 d post TNBS,the pathological score and myeloperoxidase(MPO)activity in all TNBS treated rats were significantly elevated compared to that of the control(9.48±1.86,8.18±0.67,5.78± 0.77 vs 0,and 3.55±1.11,1.80±0.82,0.97±0.08 unit/mg vs 0.14±0.01 unit/mg,P<0.05).At 4 wk post TNBS,the pathological score in high and median dose TNBS-treated rats were still significantly higher than that of the control(1.52±0.38 and 0.80±0.35 vs 0,P<0.05);(2)Intracolonic TNBS administration position affected the persistence of visceral hyperalgesia.At 4 wk post TNBS,abdominal withdrawal reflex (AWR)threshold pressure in all TNBS-treated groups were decreased compared to that of the control(21.52 ±1.73 and 27.10±1.94 mmHg vs 34.44±1.89 mmHg,P<0.05).At 8 wk post TNBS,AWR threshold pressure in 8 cm administration group was still significantly decreased(23.33±1.33 mmHg vs 36.79±2.29 mmHg,P<0.05);(3)Ethanol percentage affected the TNBS-induced inflammation severity and visceral hyperalgesia.In TNBS-25%ethanol-treated group,the pathological score and MPO activity were significantly lowered compared to that of the TNBS-50%ethanoltreated group,while AWR threshold pressure were significantly elevated(36.33±0.61 mmHg vs 23.33±1.33 mmHg,P<0.05);and(4)TNBS(5 mg/0.8 mL per rat, in 50%ethanol,8 cm from anus)-treated rats recovered completely from the inflammation with acquired visceral hyperalgesia and EC cell hyperplasia at 4 wk after TNBS administration.CONCLUSION:TNBS dosage,concentration,intraco-lonic administration position,and ethanol percentage play important roles in developing visceral hyperalgesia and EC cell hyperplasia of TNBS-induced PI-IBS rats. | Hong-Yan Qin Hai-Tao Xiao Justin CY Wu Brian M Berman Joseph JY Sung Zhao-Xiang Bian | 2012 | World Journal of Gastroenterology2012，18，20： | 10 |
| 3 | RANKL/RANK control Brca1 mutation-driven mammary tumors显示文摘 | Verena Sig Kwadwo Owusu-Boaitey Puma A Joshi Anoop Kavirayani Gerald Wimsberger Maria Novatchkova Ivona Kozieradzki Daniel Schramek Nnamdi Edokobi Jerome Hersl Aishia Sampson Ashley Odai-Afotey Conxi Lazaro Eva Gonzalez-Suarez Miguel A Pujaaa for CIMBA Holger Heyn Enrique Vidal Jennifer Cru. ickshank Hal Berman Renu Sarao Melita Tieevic Iris Uribesalgo Luigi Tortola Shuan Rao Yen Tan Georg Pfeiler Eva YHP Lee Zsuzsanna Bago-Horvath Lukas Kenner Helmuth Popper Christian Singer Rama Khokha LaundeRe P Jones Josef M Penninger | 2016 | Cell Research2016，26，7： | 3 |
| 4 | 冠状动脉钙化在高血压患者心血管病风险分层中的作用显示文摘研究者研究了冠状动脉钙化(coronary artery calcium,CAC)在成人高血压心血管病风险分层中的作用,包括符合收缩压干预试验(systolic blood pressure intervention trial,SPRINT)标准的患者。此外,研究者使用CAC来确定心血管病死亡率与SPRINT中标准降压组心血管病死亡率('SPRINT水平')相当的高血压成年患者,其可能受益于强化降压治疗。研究人群包括来自CAC研究联盟的高血压患者16 167例,其中6375例患者构成'SPRINT类似人群'。研究者按CAC分类(0,1~99,100~399,≥400)比较了多因素校正后的冠状动脉粥样硬化性心脏病(冠心病)和心血管病死亡风险比。 | 刘青(译) 叶鹏(摘、审校) Uddin SMI Mirbolouk M Kianoush S Orimoloye OA Dardari Z Whelton SP Miedema MD Nasir K Rumberger JA Shaw LJ Berman DS Budoff MJ McEvoy JW Matsushita K Blaha MJ Graham G | 2019 | 中华高血压杂志2019，27，5： | 3 |
| 5 | Adiponectin Levels do not Change with Moderate Dietary Induced Weight Loss and Exercise in Obese Postmenopausal Women显示文摘 | Nickla S B J Berman D M | 2003 | Int J Obes Re-latMetab2003，27，： | 1 |
| 6 | An- alysis of Moisture-induced Stresses in an FRP Composites Reinforced Masonry Structure 显示文摘 | KHOSHBAKHT M LIN M W BERMAN J B | 2006 | Finite Elements in Analysis and Design2006，42，5： | 1 |
| 7 | Correlates of levels and pat- terns of positive life changes following sexual assault 显示文摘 | Frazier P Tashiro T Berman M | 2004 | J Con- suit Clin Psychol2004，72，1： | 1 |
| 8 | Experimental and analytical investigation of tubular links for eccentrically braced frames 显示文摘 | Berman J W Bruneau M | 2007 | Engineering Structures2007，29，8： | 1 |
| 9 | Experimental evidence of nutrients limiting the production of micro-anoplankton and ultraplankton in the coastal waters of the eastern Mediterranean ocean(Haifa, Israel)显示文摘 | Bonin D J Bonin M C Berman T | 1989 | Aquat Sci1989，51，： | 1 |
| 10 | Upper critical tempera-tures and forced ventilation effects for high-yielding dairy cows in a subtropical climate显示文摘 | Berman A Y Folman M Kaim M | 1985 | J Dairy Sci1985，68，： | 1 |
| 11 | Predictors of adipose tissue lipoprotein lipase in middle-aged and older men:relationship to leptin and obesity,but not cardiovascular fitness显示文摘 | BERMAN D M ROGUS E M BUSBY-WHITEHEAD M J | 1999 | Metab1999，，48： | 1 |
| 12 | The protein data bank显示文摘 | Berman H M Westbrook J Feng Z K Gilliland G Bhat T N Weissig H Shindyalov L N Bourne P E | | 0，，01： | 1 |
| 13 | The epidemiol- ogy of brain Arteriovenous Malformations显示文摘 | Berman M F Sciacca R R Pile-Spellman J | 2000 | Neurosurgery2000，47，2： | 1 |
| 14 | The role of urinary obstruction in the genesis of renal dysplasia-A model in the chick embryo显示文摘 | Maizels M | 1982 | Journal of Urology1982，128，： | 1 |
| 15 | A transformation for ordering multispectral data in terms of image quality with implications for noise removal 显示文摘 | Green A A Berman M Switzer P | 1988 | IEEE Transactions on Geoscience and Remote Sensing1988，26，1： | 1 |
| 16 | Facility relia-bility issues in network p-median problems:Strategiccentralization and co-location effects显示文摘 | Berman O Krass D Menezes M B C | 2007 | OperationResearch2007，55，2： | 1 |
| 17 | A measure of quality of life for clinical trials in chronic lung disease显示文摘 | Guyatt G Berman L Townsend M | 1987 | Thorax1987，42，： | 1 |
| 18 | A transformation for ordering multispectral data in terms of image quality with implications for noise removal显示文摘 | Green A A Berman M Switzer P | 1988 | IEEE Transac- tions on Geoscience and Remote Sensing1988，26，1： | 1 |
| 19 | Asymptotic formula for the distribution of the maximum of a Gaussian process with stationary increments 显示文摘 | Berman S M | 1985 | J Appl Prob1985，22，： | 1 |
| 20 | The renewed potential for folate antagonists in contemporary cancer chemotherapy显示文摘 | Berman E M Werbel L M | 1991 | J Med Chem1991，34，2： | 1 |
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