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| 1 | Combined administration of platelet rich plasma and autologous bone marrow aspirate concentrate for spinal cord injury: a descriptive case series显示文摘Administration of platelet rich plasma(PRP) and bone marrow aspirate concentrate(BMAC) has shown some promise in the treatment of neurological conditions;however, there is limited information on combined administration. As such, the purpose of this study was to assess safety and functional outcomes for patients administered combined autologous PRP and BMAC for spinal cord injury(SCI). This retrospective case series included seven patients who received combined treatment of autologous PRP and BMAC via intravenous and intrathecal administration as salvage therapy for SCI. Patients were reviewed for adverse reactions and clinical outcomes using the Oswestry Disability Index(ODI) for up to 1 year, as permitted by availability of follow-up data. Injury levels ranged from C3 through T11, and elapsed time between injury and salvage therapy ranged from 2.4 months to 6.2 years. Post-procedure complications were mild and rare, consisting only of self-limited headache and subjective memory impairment in one patient. Four patients experienced severe disability prior to PRP combined with BMAC injection, as evidenced by high(> 48/100) Oswestry Disability Index scores. Longitudinal Oswestry Disability Index scores for two patients with incomplete SCI at C6 and C7, both of whom had cervical spine injuries, demonstrated a decrease of 28–40% following salvage therapy, representing an improvement from severe to minimal disability. In conclusion, intrathecal/intravenous co-administration of PRP and BMAC resulted in no significant complications and may have had some clinical benefits. Larger clinical studies are needed to further test this method of treatment for patients with SCI who otherwise have limited meaningful treatment options. This study was reviewed and approved by the Ohio Health Institutional Review Board(IRB No. 1204946) on May 16, 2018. | Joseph A.Shehadi Steven M.Elzein Paul Beery M.Chance Spalding Michelle Pershing | 2021 | Neural Regeneration Research2021，16，2： | 3 |
| 2 | Impact of pediatric inflammatory bowel disease diagnosis on exercise and sports participation: Patient and parent perspectives显示文摘BACKGROUND Inflammatory bowel disease(IBD)may limit physical activity due to intestinal or extraintestinal manifestations,fatigue,or exercise perception.We sought to evaluate the influence of IBD diagnosis on exercise and sports participation in a pediatric population.We compared patient-reported and parent-reported perspectives.AIM To evaluate the influence of IBD diagnosis on exercise and sports participation in a pediatric population.METHODS Consecutive IBD outpatients(aged 10-18 years)and their parents completed parallel voluntary surveys.A validated,patient-reported functional activity scale,the Hospital for Special Surgery Pediatric Functional Activity Brief Scale(HSS Pedi-FABS)was used to assess children’s activity levels.RESULTS There were 149 completed surveys(75%response rate)with mean participant age of 16.5 years[standard deviation(SD)=4.0]and mean age at IBD diagnosis of 11.8 years(SD=3.4).Most patients(77%)were diagnosed within 12 mo of symptom onset.Current athletic participation was reported in 65%across 65 sports.Participation was greatest before(40%)rather than after(32%)IBD diagnosis,with no reported change in 28%.IBD negatively impacted play/performance in 45%but did not change play/performance in 44%.IBD treatment improved patients’desire to exercise(70%)and subjective capacity for aerobic exercise(72%).Patients and parents agreed that IBD subjects demonstrate normal capacity for aerobic exercise(0.40,95%CI:0.22-0.58)and that treatment improved both participatory desire(0.33,95%CI:0.12-0.54)and capacity for aerobic exercise(0.52,95%CI:0.31-0.71).Almost all(99%)viewed exercise as healthy,and most encouraged its practice.IBD patients demonstrated normal mean HSS Pedi-FABS scores.CONCLUSION After pediatric IBD diagnosis,most patients continue exercise and sports,with mean activity levels comparable to American youth.Treatment positively impacts participatory desire and aerobic capacity.Patients favor the role of exercise in IBD. | Renée M Marchioni Beery Enju Li Laurie N Fishman | 2019 | World Journal of Gastroenterology2019，25，31： | 2 |
| 3 | Adsorption of water from liquid-phase ethanol-water mixtures at room temperature using starch-based adsorbents 显示文摘 | Beery K E Ladisch M R | 2001 | Industrial and Engineering Chemistry Research2001，40，9： | 1 |
| 4 | Physiology of the eustachian tube in the pathogenesis and management of middle ear effusion显示文摘 | Bluestone CD Paradise JI Beery QC | 1972 | Laryngoscope1972，82，9： | 1 |
| 5 | Inheritance Hierarchy Design in Object-oriented Databases显示文摘 | BEERI C | 1999 | Data and Knowledge Engineering1999，30，： | 1 |
| 6 | Function of the Eustachian tube related to surgical management of acquired aural cholesteatoma in children显示文摘 | Bluestone CD Cantekin EI Beery QC | 1978 | Laryngoscope1978，88，7： | 1 |
| 7 | Cardiovascular risk fac- tors for Alzheimer's disease 显示文摘 | Rosendorff C Beeri MS Silverman JM | 2007 | Am J Geriatr Cardiol2007，16，3： | 1 |
| 8 | The mechanism of skin-core morphology formation in extrudates of polycarbonate/liquid crystalline polymer blends显示文摘 | Beery D Kenig S Siegman A | 1993 | Polymer Engineeringand Science1993，33，23： | 1 |
| 9 | Conducting polymer colloidal silica composites显示文摘 | Armes S P Gottesfeld S Beery J G | 1991 | Polymer1991，32，： | 1 |
| 10 | Atomicity and isolation for transactional processes显示文摘 | Heiko Schuldt Gustavo Alonso Catriel Beeri | 2002 | ACM Transactions on Database Systems2002，27，1： | 1 |
| 11 | Chemotactic be- havior of Campylobacterjejuni显示文摘 | Hugdahl M B Beery J T Doyle M P | 1988 | Infection and Immu- nity1988，56，6： | 1 |
| 12 | Daily low-dose/continuous capecitabine combined with neo-adjuvant irradiation reduced VEGF and PDGF-BB levels in rectal carcinoma patients显示文摘 | Loven D Beery E Yerushalmi R | 2008 | Acta Oncol2008，47，1： | 1 |
| 13 | Conducting polymer-colloidal silicacomposites显示文摘 | Armes P Gottesfeld S Beery J G | 1991 | Polymer1991，32，： | 1 |
| 14 | Molecular evidence of organic ion transporters in the rat adrenal cortex with adrenocorticotropin-regulated zonal expression显示文摘 | BEERY E MIDDEL P BAHN A | 2003 | Endocrinology2003，144，10： | 1 |
| 15 | Geographical model for precise agriculture monitoring with real-time remote sensing显示文摘 | Beeri O Peled A | 2009 | ISPRS Journal of Photogrammetry and Remote Sensing2009，64，1： | 1 |
| 16 | The opposing effects of endothelin-1 and C-type natriuretic peptide on apoptosis of neonatal rat cardiac myocytes显示文摘 | Han B Fixler R Beeri R | 2003 | Eur J Pharmacol2003，474，1： | 1 |
| 17 | Dependence of performance of solid polymer electrolyte fuel cells with low platinum loading on morphologic characteristics of the electrodes 显示文摘 | TICIANELLI E A BEERY J G | 1991 | J Appl Electrochem1991，21，7： | 1 |
| 18 | Quantitative Wood Anatomy Relating Anatomy to Transverse Tensile Strength显示文摘 | Beery W H Ifju G Mclain T E | 1983 | Wood Fiber Sci1983，，4： | 1 |
| 19 | Dinoflagellate cyanobacterium communication may determine the composition of phytoplankton assemblage in a mesotrophic lake显示文摘 | VARDI A SCHATZ D BEERI K | 2002 | Curr Biol2002，12，20： | 1 |
| 20 | Frequent apoptosis in human kidneys after acute renal hypoperfusion 显示文摘 | Jaffe R Ariel I Beeri R | 1997 | Exp Nephrol1997，5，5： | 1 |
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