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| 1 | Outcomes of curative esophageal cancer surgery in elderly:A metaanalysis显示文摘BACKGROUND An increasing number of older patients is undergoing curative,surgical treatment of esophageal cancer.Previous meta-analyses have shown that older patients suffered from more postoperative morbidity and mortality compared to younger patients,which may lead to patient selection based on age.However,only studies including patients that underwent open esophagectomy were included.Therefore,it remains unknown whether there is an association between age and outcome in patients undergoing minimally invasive esophagectomy.AIM To perform a systematic review on age and postoperative outcome in esophageal cancer patients undergoing esophagectomy.METHODS Studies comparing older with younger patients with primary esophageal cancer undergoing curative esophagectomy were included.Meta-analysis of studies using a 75-year age threshold are presented in the manuscript,studies using other age thresholds in the Supplementary material.MEDLINE,Embase and the Cochrane Library were searched for articles published between 1995 and 2020.Risk of bias was assessed with the Newcastle-Ottawa Scale.Primary outcomes were anastomotic leak,pulmonary and cardiac complications,delirium,30-and 90-d,and in-hospital mortality.Secondary outcomes included pneumonia and 5-year overall survival.RESULTS Seven studies(4847 patients)using an age threshold of 75 years were included for meta-analysis with 755 older and 4092 younger patients.Older patients(9.05%)had higher rates of 90-d mortality compared with younger patients(3.92%),(confidence interval=1.10-5.56).In addition,older patients(9.45%)had higher rates of in-hospital mortality compared with younger patients(3.68%),(confidence interval=1.01-5.91).In the subgroup of 2 studies with minimally invasive esophagectomy,older and younger patients had comparable 30-d,90-d and in-hospital mortality rates.CONCLUSION Older patients undergoing curative esophagectomy for esophageal cancer have a higher postoperative mortality risk.Minimally invasive esophagectomy may be important for minimizing mortality in older patients. | Nikolaj S Baranov Cettela Slootmans Frans van Workum Bastiaan R Klarenbeek Yvonne Schoon Camiel Rosman | 2021 | World Journal of Gastrointestinal Oncology2021，13，2： | 3 |
| 2 | Chinese and Uighur medicine diagnostic criteria of the evaluation of the Modern drug treatment side-effects in bronchial asthma patients显示文摘We studied Chinese and Uighur medicines and create an automated computer diagnostics system according to principals of Uighur medicine for evaluation of bronchial asthma patient′s state.498 patients with bronchial asthma were enrolled the automated computer diagnostic program.304 patients were evaluated in the process of drug and non-drug treatment.Savda asthma type of Uighur medicine do not corresponds with any of the defined clinico-pathogenetic variants of the disease.Thus,prevailing of atopic bronchial asthma with probability of 0.7 is defined with Savda categories with such as 'Lungs energy deficiency','Spleen energy deficiency' and 'Kidneys Yin deficiency'(P<0.01) variants in Chinese Medicine.The combination of infectious-dependent variant of bronchial asthma Abnormal Savda syndrome with atopy with a probability of 0.8 is accompanied by the categories of 'Hot and Full' asthma with such variants as 'Lungs energy deficiency' 'Spleen energy deficiency','Kidneys Yin deficiency'(P<0.01).Patients with an easier case of Abnormal Savda syndrome bronchial asthma in 71% of cases have prevailing diagnostic categories of 'External,Full and Cold' asthma.Patients with a harder case of Abnormal Savda in 74% of cases belongs to the categories of 'Internal,Empty and Hot' asthma.So,hormone dependency of the disease in 69% of cases is accompanied by the 'Kidneys Yin deficiency' variant and,if there is an aspirin component in the pathogenesis of mixed asthma,in 83% of cases 'Kidneys Yin deficiency' and 'Kidneys Yang deficiency' variants are defined. | Dubrovin Denis Igor Gogol Mikhail Baranov Nurmuhammat Amat Halmurat Upur | 2013 | 新疆医科大学学报2013，36，4： | 2 |
| 3 | Devices and methods used for radiation monitoring of sea water during salvage and transportation显示文摘 | Igor Baranov Igor Kharitonov Andrey Laykin | 2003 | Nuclear Instruments and Methods in Physics Research A2003，505，： | 1 |
| 4 | Expression levels influence ribosomal frameshifling at the tandem rare arginine codons AGG_ AGG and AGA_AGA in Escherichia coli显示文摘 | Gurvich O L Baranov P V Gesteland R F | 2005 | J Bacteriol2005，187，12： | 1 |
| 5 | Magnetic phase transitions, short - range correlatiom and spin fluctuatiom in (Gd1-xYx)Co 显示文摘 | Baranov N V Baranov N V Yermakov A A | 2001 | J A1 Com2001，329，： | 1 |
| 6 | Theory, design, and operation of a dynamic reaction cell for ICP-MS显示文摘 | TANNER S D BARANOV V I | 1999 | Atomic Spectroscopy1999，20，2： | 1 |
| 7 | Distribution and expression of gas seeps in a gas hydrate province of the northeastern Sakhalin continental slope,Sea of Okhotsk显示文摘 | Jin Y K Kim Y G Baranov B | | 0，，： | 1 |
| 8 | The external res- piration and gas exchange in space missions 显示文摘 | Baranov VM Tikhonov MA Kotov AN | 1992 | Acta As- tronaut1992，27，4： | 1 |
| 9 | Characterization of a-phase soft proton-exchanged LiNbO3 optical waveguides显示文摘 | KORKISHKO Y N FEDOROV V A BARANOV E A | 2001 | J Opt Soc Am2001，18，5： | 1 |
| 10 | Association between HCV RNA level and anti-HCV antibodies During chronic hepatitis C显示文摘 | Baranov AV Maleev W | 2009 | Zh Mikrobiol Epidemiol Immunobiol2009，9，5： | 1 |
| 11 | Effect of electrostatic fields mechanical characteristics and structure of metals and alloys 显示文摘 | Baranov Y V | 2000 | Materials Science and Engineering : A2000，287，2： | 1 |
| 12 | Detection of Ultratrace Phosphorus and Sulfur by Quadrupole ICPMS with Dynamic Reaction Cell显示文摘 | Bandura DR Baranov VI Tanner SD | 2002 | Analytical Chemistry2002，74，7： | 1 |
| 13 | Thermal analysis of paracetamol polymorphs by FT-IR spectroscopies显示文摘 | ZIMMERMANN B BARANOVIC G | 2011 | Journal of Phar- maceutical and Biomedical Analysis2011，54，： | 1 |
| 14 | Gene therapy of monogenic hereditary disease显示文摘 | Baraanov VS Baranov AN | 2000 | Vopr Med Khim2000，46，3： | 1 |
| 15 | Visualizing gene expression by whole-body fluorescence imaging显示文摘 | Yang M Baranov E Moossa AR | 2000 | Proc Natl Acad Sci U S A2000，97，12： | 1 |
| 16 | Hydrogen bonding and mechanical properties of thin films of poly- ether-based polyurethane-silica nanocomposites 显示文摘 | Bistricic L Baranovic G Leskovac M | 2010 | Eur Polym J2010，46，10： | 1 |
| 17 | Influence of n - Alkanes on Hardening and Selected Properties of Gelatin Shells of Microcapsules 显示文摘 | A V Baranov K N Zhelezonv | 2002 | Russian Journal of Applied Chemistry2002，75，9： | 1 |
| 18 | The external respiration and gas exchange in space missions 显示文摘 | Baranov VM Tikhonov MA Kotov AN | 1992 | Acta Astronaut1992，27，： | 1 |
| 19 | Interaction of Protein and DNA-Loaded Liposomes with Sperm Cells 显示文摘 | Boda K Brzobohaty B Baranov V S | 1987 | Folia Biol (Praha)1987，33，2： | 1 |
| 20 | A High-Density Water-Resistant Magnesia-Lime Material Based on Dolomite显示文摘 | S. A. Suvorov M. I. Nazmiev A. P. Baranov A. A. Dmitrienko | 2005 | Refractories and Industrial Ceramics2005，，3： | 1 |
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