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| 1 | 青少年及儿童近视进展及其危险因素显示文摘近视是全球重要的公共卫生问题。青少年及儿童近视患病率因在全球范围,尤其在亚洲地区,快速增长且影响因素复杂多样而受到广泛关注。尽管目前已有大量关于青少年及儿童近视进展及其危险因素的报道,然而由于人群、近视定义、睫状肌麻痹剂、验光方法等不同导致彼此间难以比较。本文就1990年至今关于青少年(〈18岁)和儿童近视进展及其与年龄、性别、屈光状态、近距工作、户外活动、父母近视或父母生育年龄等危险因素关系的报道进行总结。 | 林仲 梁远波 李晓霞 Balamurali Vasudevan Kenneth J Ciuffreda | 2015 | 中华实验眼科杂志2015，33，12： | 12 |
| 2 | Comparison of ocular modulation transfer function determined by a ray-tracing aberrometer and a double-pass system in early cataract patients显示文摘 | Qiao Liya Wan Xiuhua Cai Xiaogu Balamurali Vasudevan Xiong Ying Tan Jiaxuan Guan Zheng David A Atchison Wang Ningli | 2014 | Chinese Medical Journal2014，，19： | 3 |
| 3 | Intravenous immune globulin suppresses angiogenesis in mice and humans显示文摘Human intravenous immune globulin(IVIg),a purified IgG fraction composed of~60%IgG1 and obtained from the pooled plasma of thousands of donors,is clinically used for a wide range of diseases.The biological actions of IVIg are incompletely understood and have been attributed both to the polyclonal antibodies therein and also to their IgG(IgG)Fc regions.Recently,we demonstrated that multiple therapeutic human IgG1 antibodies suppress angiogenesis in a target-independent manner via FcγRI,a high-affinity receptor for IgG1.Here we show that IVIg possesses similar anti-angiogenic activity and inhibited blood vessel growth in five different mouse models of prevalent human diseases,namely,neovascular age-related macular degeneration,corneal neovascularization,colorectal cancer,fibrosarcoma and peripheral arterial ischemic disease.Angioinhibition was mediated by the Fc region of IVIg,required FcγRI and had similar potency in transgenic mice expressing human FcγRs.Finally,IVIg therapy administered to humans for the treatment of inflammatory or autoimmune diseases reduced kidney and muscle blood vessel densities.These data place IVIg,an agent approved by the US Food and Drug Administration,as a novel angioinhibitory drug in doses that are currently administered in the clinical setting.In addition,they raise the possibility of an unintended effect of IVIg on blood vessels. | Reo Yasuma Valeria Cicatiello Takeshi Mizutani Laura Tudisco Younghee Kim Valeria Tarallo Sasha Bogdanovich Yoshio Hirano Nagaraj Kerur Shengjian Li Tetsuhiro Yasuma Benjamin J Fowler Charles B Wright Ivana Apicella Adelaide Greco Arturo Brunetti Balamurali K Ambati Sevim Barbasso Helmers Ingrid E Lundberg Ondrej Viklicky Jeanette HW Leusen J Sjef Verbeek Bradley D Gelfand Ana Bastos-Carvalho Sandro De Falco Jayakrishna Ambati | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 3 |
| 4 | 促红细胞生成素(Epo)及其受体(EpoR)在正常及碱烧伤诱导的鼠新生血管化角膜上的表达(英文)显示文摘目的:促红细胞生成素(Epo)是促红细胞生成的因子,由胎儿肝脏和成人肾脏产生,是贫血及缺氧时的一种应答反应。视网膜异常血管形成,如早产儿视网膜病变(ROP),增殖性糖尿病性视网膜病变(PDR)时Epo水平增高,提示Epo在病理性眼部血管生成中的作用。Epo参与视网膜血管生成,但其与角膜新生血管是否有关尚未见报道。本研究旨在探讨Epo/EpoR是否在正常和新生血管化角膜表达及角膜内注射Epo是否可诱发角膜新生血管的产生,从而了解其与角膜新生血管的联系。方法:(1)制备碱烧伤诱导鼠角膜新生血管模型,免疫组织化学的方法检测Epo及EpoR是否在正常角膜及新生血管化角膜表达;(2) Epo的克隆、表达及纯化;(3)角膜基质内分别注射Epo(6μL,1μg)及Epo对照(载体对照)及盐水,第14d观察角膜是否有新生血管产生。结果:Epo及EpoR在正常角膜及碱诱发的新生血管化角膜的角膜上皮细胞,角膜内皮细胞,基质细胞均有表达,并在新生血管化角膜表达加强,同时也在基质内炎症细胞及新生血管均有表达。角膜基质内注射Epo后第14d,6眼中5眼产生新生血管,对照组6眼均未见新生血管。结论:本文首次报道了Epo及其受体表达于正常角膜和新生血管化角膜。角膜内注射注射Epo可诱发角膜新生血管。Epo及其受体系统与角膜新生血管化的形成有关。 | 罗灵 Yuuki Kaminoh 陈浩宇 张卯年 张康 Balamurali K Ambati | 2008 | 国际眼科杂志2008，8，5： | 3 |
| 5 | Thorotrast-induced primary cerebral angiosarcoma:case report 显示文摘 | BALAMURALI G PLESSIS DG WENGOY M | 2009 | Neurosurgery2009，65，： | 1 |
| 6 | Excited state intrarnolecular proton transfer in 2 - (2'-amino-3-pyridyl) -benzimidazole : effect of solvents显示文摘 | BALAMURALI M M DOGRA S K | 2004 | Chem Phys2004，305，： | 1 |
| 7 | Citric acid as a feed stimulant 显示文摘 | Aravindan C M | 1997 | Fish Techol Soc Fish Technol India1997，34，1： | 1 |
| 8 | Optimal design of step-stress degradation tests in the case of destructive measurement显示文摘 | Park S J Yum B J Balamurali S | 2004 | Quality Technology & Quantitative Management2004，1，1： | 1 |
| 9 | Anterior thoracic forami-notomy through mini-thoracotomy for the treatment of giant thoracic disc herniations显示文摘 | Russo A Balamurali G Nowicki R | 2012 | Eur SpineJ2012，212，： | 1 |
| 10 | Citric acid as a feed stimulant显示文摘 | Aravindan C M | 1997 | Fish Techol Soc Fish Technol India1997，34，1： | 1 |
| 11 | Optimal design of step-stress degradation tests in the case of destructive measurement显示文摘 | PARK S J YUM B J BALAMURALI S | 2004 | Quality Technology & Quantitative Management2004，1，1： | 1 |
| 12 | Age-Related Macular degeneration: etiology pathogenesis and the repeutic strategies 显示文摘 | Jayakrishna A Balamurali KA | 2003 | SurvOpthalmol2003，48，： | 1 |
| 13 | Evalution and design of two level continuous sampling plans显示文摘 | Jun C H Balamurali S Kalyanasundaram M | 2006 | TamkangJournal of Science and Engineering2006，9，4： | 1 |
| 14 | Optimal designing of a skip lot sampling plan by two point method显示文摘 | Aslam M Balamurali S Jun C H | 2010 | Pakistan Journal of Statistics2010，26，4： | 1 |
| 15 | Age-Related Macular Degeneration: etiology, pathogenesis, and therapertic Strategies显示文摘 | Jayakrishna A Balamurali KA | 2003 | Sur of Ophthalmol2003，48，： | 1 |
| 16 | Bootstrap lower confidence limits for the process capability indices Cp,Cpk andCpm显示文摘 | Balamurali S Kalyanasundaram M | 2002 | International Journal of Quality & Reliability Management2002，19，8： | 1 |
| 17 | Hydrogen Generation in a Pd Membrane Fuel Processor:Assessment of Methanol-based Reaction Systems显示文摘 | Harold Michael Nair Balamurali Kolios Gregor | 2003 | Chemical Engineering Science2003，58，： | 1 |
| 18 | Citric acid as a feed stimulant显示文摘 | Balamurali R S Arabindan C M | 1983 | Fish Techol Soc Fish Technol India1983，，： | 1 |
| 19 | Citric acid as a feed stimulant显示文摘 | Balamurali R S Arayindan C M | 1997 | Fishery Technology1997，34，1： | 1 |
| 20 | Toll like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin显示文摘 | Jing Z Keping X Balamurali A | 2003 | Inves Ophthalmol Vis Sci2003，44，10： | 1 |
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