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| 1 | 腹腔镜右半结肠癌完整结肠系膜切除术的可行性和安全性:一项随机临床研究的短期结果显示文摘目的:这项前瞻性研究旨在比较接受腹腔镜右半结肠癌完整结肠系膜切除术(complete mesocolic excision,CME)与常规右半结肠切除术(non-CME,NCME)患者的短期疗效。背景:CME联合中央血管结扎可降低腹腔镜右半结肠癌切除术后局部复发率,改善术后5年癌症相关生存情况,但这项操作因可增加手术并发症而存在额外的风险。由此,目前对此尚存争议。方法:这项随机对照试验的主要终点是手术时间、术中出血量、中转开腹率、吻合口漏,以及其他并发症,次要终点是总体术后并发症。此外,还评估了与肿瘤学结局相关的组织病理学数据,包括标本长度和淋巴结检出数量(作为CME手术质量的客观评价指标)。结果:CME组的平均手术时间长于NCME组(216.3 min vs.191.5 min,P=0.005)。然而,CME组的淋巴结检出数量更多(23.8枚vs.16.6枚,P<0.001),手术标本更长(34.3 cm vs.29.3 cm,P=0.002)。两组术中出血量、中转开腹率、吻合口漏发生率和其他术后并发症发生率比较差异均无统计学意义。结论:根据本研究所得认为,腹腔镜CME是一种安全可行的手术方法,可以提高淋巴结的检出效果、增加手术标本的长度,且未见增加术中和术后并发症。 | 孙凌宇 DI BUONO G BUSCEMI S COCORULLO G | 2021 | 结直肠肛门外科2021，27，1： | 13 |
| 2 | CHK2 kinase in the DNA damage response and beyond显示文摘serine/threonine kinase CHK2 是 DNA 损坏反应的一个关键部件。在人的房间,跟随 genotoxic 应力, CHK2 被激活并且 phosphorylates >导致适当细胞的反应的 20 蛋白质,它,取决于损坏,房间类型,和另外的因素的程度,能是房间周期检查点激活, apoptosis 或老朽感应, DNA 修理,或损坏的忍耐。最近, CHK2 也被发现了有独立于原子 DNA 损害的存在的细胞的功能。特别地, CHK2 参予涉及 DNA 结构修正和房间周期前进的几个分子的过程。在这评论,我们在不着重的房间响应 DNA 损坏并且在生物功能的维护讨论 CHK2 的活动。这些活动也在 tumorigenesis 在与 CHK2 的一个可能的角色的关系被考虑并且作为后果,作为癌症的一个目标治疗。 | Laura Zannini Domenico Delia Giacomo Buscemi | 2014 | Journal of Molecular Cell Biology2014，8，6： | 12 |
| 3 | Impact of the COVID-19 pandemic on liver donation and transplantation:A review of the literature显示文摘The coronavirus disease 2019(COVID-19)pandemic has upended healthcare systems worldwide and led to an inevitable decrease in liver transplantation(LT)activity.During the first pandemic wave,administrators and clinicians were obliged to make the difficult decision of whether to suspend or continue a lifesaving procedure based on the scarce available evidence regarding the risk of transmission and mortality in immunosuppressed patients.Those centers where the activity continued or was heavily restricted were obliged to screen donors and recipients,design COVID-safe clinical pathways,and promote telehealth to prevent nosocomial transmission.Despite the ever-growing literature on COVID-19,the amount of high-quality literature on LT remains limited.This review will provide an updated view of the impact of the pandemic on LT programs worldwide.Donor and recipient screening,strategies for waitlist prioritization,and posttransplant risk of infection and mortality are discussed.Moreover,a particular focus is given to the possibility of donor-to-recipient transmission and immunosuppression management in COVID-positive recipients. | Riccardo De Carlis Ivan Vella NiccolòIncarbone Leonardo Centonze Vincenzo Buscemi Andrea Lauterio Luciano De Carlis | 2021 | World Journal of Gastroenterology2021，27，10： | 4 |
| 4 | Liver transplantation in the treatment of severe iatrogenic liver injuries显示文摘The place of liver transplantation in the treatment of severe iatrogenic liver injuries has not yet been widely discussed in the literature. Bile duct injuries during cholecystectomy represent the leading cause of liver transplantation in this setting, while other indications after abdominal surgery are less common. Urgent liver transplantation for the treatment of severe iatrogenic liver injury may-represent a surgical challenge requiring technically difficult and time consuming procedures. A debate is ongoing on the need for centralization of complex surgery in tertiary referral centers. The early referral of patients with severe iatrogenic liver injuries to a tertiary center with experienced hepato-pancreatobiliary and transplant surgery has emerged as the best treatment of care. Despite widespread interest in the use of liver transplantation as a treatment option for severe iatrogenic injuries, reported experiences indicate few liver transplants are performed. This review analyzes the literature on liver transplantation after hepatic injury and discusses our own experience along with surgical advances and future prospects in this uncommon transplant setting. | Andrea Lauterio Riccardo De Carlis Stefano Di Sandro Fabio Ferla Vincenzo Buscemi Luciano De Carlis | 2017 | World Journal of Hepatology2017，9，24： | 4 |
| 5 | Chk2 and REGγ-dependent DBC1 regulation in DNA damage induced apoptosis显示文摘 | Magni M Ruscica V Buscemi G | 2014 | Nucleic Acids Res2014，42，13： | 1 |
| 6 | Engraftment capacity of mesenchymal cells following hematopoietie stem cell transplantation in patients receiving reduced-intensity conditioning regimen 显示文摘 | Poloni A Leoni P Buscemi L | 2006 | Leukemia2006，20，2： | 1 |
| 7 | Advantage of Eradication Therapy for Helicobacter pylori Before Kidney Transplantation in Uremic Patients显示文摘 | G. Cocchiara M. Romano G. Buscemi C. Maione S. Maniaci G. Romano | 2007 | Transplantation Proceedings2007，，10： | 1 |
| 8 | Extragonadal testicular tumors显示文摘 | Utz D C Buscemi M F | 1971 | J Urol1971，105，2： | 1 |
| 9 | Enteral nutrition in pancreaticoduodenectomy: a literature review 显示文摘 | Buscemi S Damiano G Palumbo VD | 2015 | Nutrients2015，7，5： | 1 |
| 10 | Polymorphism and sequence variations of the HumCD4 pentameric microsatellite in an Italian population sample显示文摘 | TAGLIABRACCI A BUSCEMI L BIANCHI F | 1998 | J Forensic Sci1998，43，4： | 1 |
| 11 | Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction:meta-analysis显示文摘 | Buscemi N Vandermeer B Hooton N | 2006 | BMJ2006，332，7538： | 1 |
| 12 | A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage显示文摘 | Carlessi L Buscemi G Fontanella E | 2010 | Biochim Biophys Acta2010，1803，10： | 1 |
| 13 | Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction:metaanalysis显示文摘 | Buscemi N Vandermeer B Hooton N | | 0，，： | 1 |
| 14 | Glycaemic variability using continuous glucose monitoring and endothelial function in the metabolic syndrome and in Type 2 diabetes显示文摘 | Buscemi S Re A Batsis JA | 2010 | Diabet Med2010，27，8： | 1 |
| 15 | Inguinal hernioplasty improves the quality of life in patients with cirrhosis显示文摘 | Patti R Almasio PL Buscemi S | 2008 | Am J Surg2008，196，3： | 1 |
| 16 | A novel method of dynamic culture surface expansion improves mesenchymal stem cell prolif- eration and phenotype显示文摘 | Maid H Wipff PJ Buscemi L | 2009 | Stem Cells2009，27，： | 1 |
| 17 | New communications solutionsfor ESA ground stations显示文摘 | Bertelsmeier M Buscemi G | 2006 | ESA Bulletin2006，，125： | 1 |
| 18 | The efficacy and safety of drug treatments for chronic insomnia in adults : a meta - analysis of RCTs 显示文摘 | BUSCEMI N VANDERMEER B FRIESEN C | 2007 | J Gen Intern Med2007，22，9： | 1 |
| 19 | Analysis of Bioglass Fixation of Hip Prostheses 显示文摘 | Hench L Pantano Jr C Buscemi P | 1977 | Journal of Biomedical Materials Research1977，11，2： | 1 |
| 20 | Challenges and opportunities for Corterra PIT in textile fibers 显示文摘 | Buscemi M Dangayach D | 2002 | Chemical Fibers Internatioal2002，52，： | 1 |
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