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| 1 | Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs显示文摘AIM To investigate the long-term effect of dietary education on a low fermentable oligosaccharide, disaccharide and polyol(FODMAP) diet on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS Participants with IBS(Rome III) were randomized to two groups. Group I commenced a low FODMAP diet at baseline. At three months, group II, so far a comparator group, crossed over to a low FODMAP diet while group I started re-challenging foods. All patients completed the IBS SSS(IBS symptom severity scoring system, 0-500 points increasing with severity), IBS Qo L questionnaire(0-100 increasing with Qo L), a FODMAP specific food frequency questionnaire and provided a stool sample at baseline, three and six months for microbiome analysis.RESULTS Fifty participants were enrolled into group I(n = 23) or group II(n = 27). Participants in both groups were similar in baseline values but with more men in group I. There was a significantly lower IBS SSS(275.6 ± 63.6 to 128.8 ± 82.5 vs 246.8 ± 71.1 to 203.6 ± 70.1)(P < 0.0002) and increased Qo L(68.5 ± 18.0 to 83 ± 13.4 vs 72.9 ± 12.8 to 73.3 ± 14.4)(P < 0.0001) in group I vs group II at 3 mo. The reduced IBS SSS was sustained at 6 mo in group I(160 ± 102) and replicated in group II(124 ± 76). Fiber intake decreased on the low FODMAP diet(33 ± 17 g/d to 21 ± 8 g/d)(P < 0.01) and after re-introducing FODMAP containing foods increased again to 27 ± 9 g/d. There was no change seen in the intestinal microbiome when participants adopted a low FODMAP diet.CONCLUSION This study demonstrated that a reduction in FODMAPs improves symptoms in IBS and this improvement can be maintained while reintroducing FODMAPs. | Ruth M Harvie Alexandra W Chisholm Jordan E Bisanz Jeremy P Burton Peter Herbison Kim Schultz Michael Schultz | 2017 | World Journal of Gastroenterology2017，23，25： | 5 |
| 2 | Predictive modelling of ferroelectric tunnel junctions显示文摘Ferroelectric tunnel junctions combine the phenomena of quantum-mechanical tunnelling and switchable spontaneous polarisation of a nanometre-thick ferroelectric film into novel device functionality.Switching the ferroelectric barrier polarisation direction produces a sizable change in resistance of the junction—a phenomenon known as the tunnelling electroresistance effect.From a fundamental perspective,ferroelectric tunnel junctions and their version with ferromagnetic electrodes,i.e.,multiferroic tunnel junctions,are testbeds for studying the underlying mechanisms of tunnelling electroresistance as well as the interplay between electric and magnetic degrees of freedom and their effect on transport.From a practical perspective,ferroelectric tunnel junctions hold promise for disruptive device applications.In a very short time,they have traversed the path from basic model predictions to prototypes for novel non-volatile ferroelectric random access memories with non-destructive readout.This remarkable progress is to a large extent driven by a productive cycle of predictive modelling and innovative experimental effort.In this review article,we outline the development of the ferroelectric tunnel junction concept and the role of theoretical modelling in guiding experimental work.We discuss a wide range of physical phenomena that control the functional properties of ferroelectric tunnel junctions and summarise the state-of-the-art achievements in the field. | Julian P Velev John D Burton Mikhail Ye Zhuravlev Evgeny Y Tsymbal | 2016 | npj Computational Materials2016，，1： | 2 |
| 3 | Pulsed plasma thruster 显示文摘 | Burton R L Turch P J | 1998 | Journal of Propulsion and Power1998，14，5： | 1 |
| 4 | Relationship between tobacco-specific nitrosamines and nitrate from different air-cured tobacco varieties显示文摘 | BURTON H R DYE N K BUSH L P | 1994 | Agric food Chem1994，42，： | 1 |
| 5 | Relation between Tobacco Varieties显示文摘 | BURTON H R NAEWANNE K D BUSH L P | 1992 | J Agric Food Chem1992，42，： | 1 |
| 6 | Aggressive Reactions to Abusive Supervision:The Role of Interactional Justice and Narcissism 显示文摘 | BURTON J P HOOBLER J M | 2011 | Scandinavian Journal of Psychology2011，52，4： | 1 |
| 7 | Radiosurgery for spinal metastases: clinical experience in 500cases from a single institution显示文摘 | Gerszten P C Burton S A Ozhasoglu C | 2007 | Spine (Phi la Pal976)2007，32，2： | 1 |
| 8 | Induction of replicative senescence biomarkers by sub- lethal oxidative stresses in normal human fibroblast 显示文摘 | Dumont P Burton M Chen QM Gonos ES Frippiat C Mazarati JB | 2000 | Free Radic Biol Med2000，28，3： | 1 |
| 9 | Distribution of tobacco-specific nitr osamines in tobacco leaf tissue (1)tobacco-specific, nitrate and alkaloids显示文摘 | Burton H R Dye N K Bush L P | 1989 | J Agric Food Chem1989，40，： | 1 |
| 10 | 显示文摘 | Burton B P Cockayne E | 1999 | Physical Review B1999，60，12： | 1 |
| 11 | Point prevalence survey of antibiotic use in Scottish hospitals utilising the Glasgow Anti- microbial AuditTool (GAAT)显示文摘 | Seaton RA Nathwani I) Burton P | 2007 | Int J Antimicrob Agents2007，29，6： | 1 |
| 12 | An Investigation into the Characteristic of a Two Dimensional”2D”Flow control Valve显示文摘 | Ruan J Burton R U krainetz P | | 0，，01： | 1 |
| 13 | Influence of temperature and humidity on accumulation of tobacco-specific nitrosamines in stored burley tobacco 显示文摘 | Burton H R Bush L P Djordjevic M V | 1989 | Journal of Agriculture and Food Chemistry1989，37，： | 1 |
| 14 | Altered expression of cellular genes in neutrophils of pefiparturient dairy cows显示文摘 | aMadsen S A Weber P S Burton J L | 2002 | Veterinary immunology and immunopathology2002，86，34： | 1 |
| 15 | The procell death bcl-2 family member,BNIP3,is localized to the nucleus of human glialcells:implications for glioblastoma multiforme tumor cells urvival under hypoxia显示文摘 | HENSON E S BAIJAL P | 2006 | Int J Cancer2006，118，7： | 1 |
| 16 | Sustainable management of Canada's boreal forests:progress and prospects显示文摘 | Burton P J C Messier W L Adamowicz | 2006 | Ecoscience2006，13，2： | 1 |
| 17 | Schistosoma mansoni egg antigens induce Treg that participate in diabetes prevention in NOD mice显示文摘 | Zaccone P Burton O Miller N | 2009 | Eur J Immunol2009，39，4： | 1 |
| 18 | A phase II1 trial comparing CHOP to PMitCEBO with or without G-CSF in patients aged 60 plus with ag- gressive non-Hodgkin' s lymphoma显示文摘 | Burton C Linch D Hoskin P | 2006 | Br J Cancer2006，94，6： | 1 |
| 19 | Influence of temperature and humidity on accumulation of tobacco-specific nitrosamines in stored burley tobacco显示文摘 | BURTON H R BUSH L P DJORDJEVIC M V | 1989 | Journal of Agricultural and Food Chemistry1989，37，： | 1 |
| 20 | An NMR study of conformations of substituted dipep- tides in dodecylphosphocholine micelles: implications for drug transport显示文摘 | Kloosterman D A Goodwin J T Burton P S | 2000 | Biopolymers2000，53，5： | 1 |
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