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| 1 | Endoscopic management of esophageal varices显示文摘The rupture of gastric varices results in variceal hemorrhage, which is one the most lethal complications of cirrhosis. Endoscopic therapies for varices aim to reduce variceal wall tension by obliteration of the varix. The two principal methods available for esophageal varices are endoscopic sclerotherapy (EST) and band ligation (EBL). The advantages of EST are that it is cheap and easy to use, and the injection catheter fits through the working channel of a diagnostic gastroscope. Endoscopic variceal ligation obliterates varices by causing mechanical strangulation with rubber bands. The following review aims to describe the utility of EBL and EST in different situations, such as acute bleeding, primary and secondary | Joaquin Poza Cordon Consuelo Froilan Torres Aurora Burgos García Francisco Gea Rodriguez Jose Manuel Suárez de Parga | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，7： | 27 |
| 2 | Sustained low diffusing capacity in hepatopulmonary syndrome after liver transplantation显示文摘AIM: To study the presence of sustained low diffusing capacity (DLCO) after liver transplantation (LT) in patients with hepatopulmonary syndrome (HPS).METHODS: Six patients with mild-to-severe HPS and 24 without HPS who underwent LT were prospectively followed before and after LT at mid-term (median, 15 mo). HPS patients were also assessed at long-tem (median, 86 mo).RESULTS: Before LT, HPS patients showed lower PaO2 (71 ± 8 mmHg), higher AaPO2 (43 ± 10 mmHg) and lower DLCO (54% ± 9% predicted), due to a combination of moderate-to-severe ventilation-perfusion (VA/Q) imbalance, mild shunt and diffusion limitation, than non-HPS patients (94 ± 4 mmHg and 19 ± 3 mmHg, and 85% ± 3% predicted, respectively) (P < 0.05 each). Seven non-HPS patients had also reduced DLCO (70% ± 4% predicted).At mid- and long-term after LT, compared to pre-LT, HPS patients normalized PaO2 (91 ± 3 mmHg and 87 ± 5 mmHg), AaPO2 (14 ± 3 mmHg and 23 ± 5 mmHg) and all VA/Q descriptors (P < 0.05 each) without changes in DLCO (53% ± 8% and 56% ± 7% predicted, respectively). Post-LT DLCO in non-HPS patients with pre-LT low DLCO was unchanged (75% ± 6% predicted).CONCLUSION: While complete VA/Q resolution in HPS indicates a reversible functional disturbance, sustained low DLCO after LT also present in some non-HPS patients, points to persistence of sub-clinical liver-induced pulmonary vascular changes. | Graciela Martínez-Pallí Federico P Gómez Joan A Barberà Miquel Navasa Josep Roca Robert Rodríguez-Roisin Felip Burgos Conchi Gistau | 2006 | World Journal of Gastroenterology2006，12，36： | 6 |
| 3 | CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes显示文摘CD5 is constitutively expressed on T cells and a subset of mature normal and leukemic B cells in patients with chronic lymphocytic leukemia(CLL).Important functional properties are associated with CD5 expression in B cells,including signal transducer and activator of transcription 3 activation,IL-10 production and the promotion of B-lymphocyte survival and transformation.However,the pathway(s)by which CD5 influences the biology of B cells and its dependence on B-cell receptor(BCR)co-signaling remain unknown.In this study,we show that CD5 expression activates a number of important signaling pathways,including Erk1/2,leading to IL-10 production through a novel pathway independent of BCR engagement.This pathway is dependent on extracellular calcium(Ca2+)entry facilitated by upregulation of the transient receptor potential channel 1(TRPC1)protein.We also show that Erk1/2 activation in a subgroup of CLL patients is associated with TRPC1 overexpression.In this subgroup of CLL patients,small inhibitory RNA(siRNA)for CD5 reduces TRPC1 expression.Furthermore,siRNAs for CD5 or for TRPC1 inhibit IL-10 production.These findings provide new insights into the role of CD5 in B-cell biology in health and disease and could pave the way for new treatment strategies for patients with B-CLL. | Soizic Garaud Taher E Taher Marjolaine Debant Miguel Burgos Sarra Melayah Christian Berthou Kaushal Parikh Jacques-Olivier Pers Damien Luque-Paz Gilles Chiocchia Maikel Peppelenbosch David A Isenberg Pierre Youinou Olivier Mignen Yves Renaudineau Rizgar A Mageed | 2018 | Cellular & Molecular Immunology2018，15，2： | 2 |
| 4 | FeNb在钢液中的溶化行为及在钢包精炼过程中提高Nb收得率的最佳工艺显示文摘阐述了标准铌铁(FeNb)的微观组织特性及其溶入钢液中的研究结果。在实验室的感应炉中进行了不同温度下的非连续试验,分析了固相FeNb与钢液凝固层界面的微观组织,并与原始FeNb粒子的微观组织进行了对比。这些试验研究结果可以阐释FeNb的溶解机制和它在不同炼钢温度下的融入动力学条件。标准FeNb在钢水中溶解的试验结果证实FeNb颗粒的溶解速率高于有关文献中报告的结果,它们认为FeNb粒子的熔化温度高(>1600℃),所以在其模型中假定FeNb的溶解仅是通过固相粒子的扩散实现。本项工作得到的试验证据为标准FeNb的溶解机理提供了一种新的说法:在1500~1510℃受其共晶区的熔化行为控制,在1530~1575℃温度范围内则由初始板条相的熔化行为所主导,也就是说,均低于1600℃左右的炼钢温度。根据这些研究结果和炼钢厂已有的生产经验,对于微合金化钢在二次精炼阶段加入FeNb推荐了最优的工艺。 | Edmundo Burgos Cruz Daniel Pallos Fridman Marcelo C Carboni Rogério Contato Guimares Marcos A Stuart Nogueira Ferdinando Luiz Cavallante 王厚昕 | 2010 | 世界钢铁2010，，6： | 2 |
| 5 | Biocide tolerance in bacteria 显示文摘 | Morente E O FernandezFuentes M A Burgos M J | 2013 | Int J Food Microbiol2013，162，1： | 1 |
| 6 | A moisture -in -oil model tor power transformer monitoring - part II: experimental verification 显示文摘 | GARCIA B BURGOS J C ALONSO A | 2005 | IEEE Transactions on Power Delivery2005，20，2： | 1 |
| 7 | Classification and manage- ment of leaks after gastric bypass for patients with morbid obe- sity: a prospective study of 60 patients 显示文摘 | Csendes A Burgos AM Braghetto I | 2012 | Obes Surg2012，22，6： | 1 |
| 8 | Gremlin A Novel Mediator of Epithelial Mesenchymal Transition and Fibrosis in Chronic Allograft Nephropathy显示文摘 | Carvajal G Droguett A Burgos ME | 2008 | Transplantation Transplant Proc2008，40，3： | 1 |
| 9 | Effect of C - reactive protein on Fegamma receptor U in cultured bovine endothelial cells 显示文摘 | Escribano - Burgos M Lopez - Farre A Del Mar Gonzalez M | 2005 | Clin Sci (Lond)2005，108，1： | 1 |
| 10 | Genetic diversity of weedy red rice (Oryza sativa) in Arkansas,USA显示文摘 | Shivrain V K Burgos N R Agrama H A | 2010 | Weed Research2010，50，： | 1 |
| 11 | Role of fumonisin B1 on the immune system, histopathology, and muscle proteins of white shrimp ( Litopenaeus vannamei) 显示文摘 | Mexl6- Salazar A L Hern6ndez - L6pez J Burgos -Hern~mdez A | 2008 | Food Chem2008，110，2： | 1 |
| 12 | Pediatric invasive as-pergillosis:a multieenter retrospective analysis of 139 contemporary cRfles显示文摘 | Burgos A Zaoutis TE Dvorak CC | 2008 | Pediatrics2008，121，5： | 1 |
| 13 | Histology and proteinu ria after renal transplantation显示文摘 | Seron D Burgos D Alonso A | 2012 | Transplant Rev (Orlando)2012，26，： | 1 |
| 14 | Pediatric invasive as- pergillosis~ a multicenter retrospective analysis of 139 con- tem- porary cases显示文摘 | Burgos A Zaoutis TE Dvorak CC etal | 2008 | Pediatrics2008，121，5： | 1 |
| 15 | Prediction of Ammonia Emission from Dairy Cattle Manure Based on Milk Urea Nitrogen:Re-lation of Milk Urea Nitrogen to Urine Urea Nitrogen Excretion显示文摘 | Burgos S A J G Fadel | 2007 | J Dairy Sci2007，90，： | 1 |
| 16 | Prediction of am monia emissions from dairy cattle manure based on milk urea ni trogen: Relation of milk urea nitrogen to urine urea nitrogen ex cretion显示文摘 | Burgos S A Embertson N M Zhao Y | 2010 | J DairySci2010，93，6： | 1 |
| 17 | The effects of leptin receptor(LEPR)and melanocortin-4 receptor(MC4R)polymorphisms on fat content,fat distribution and fat composition in a Duroc×Landrace/Large White cross显示文摘 | Galve A Burgos C Silió L | 2012 | Livestock Science2012，145，3： | 1 |
| 18 | Risk HLA -DQAI and PLA(2) R1 alleles in idiopathic membranous ne phropathy显示文摘 | Stanescu HC Arcos - Burgos M Medlar A | 2011 | N Engl J Med2011，364，7： | 1 |
| 19 | Free Radical Production by Manothermosonication显示文摘 | VERCET A LOPEZ P BURGOS J | 1998 | Ultrasonics1998，36，2： | 1 |
| 20 | Endoseopic management of esophageal variees显示文摘 | Poza Cordon J Froilan Torrea C Burgos Gareia A | 2012 | World J Gastrointest Endose2012，4，7： | 1 |
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