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| 1 | A 2.8 Ma record of environmental evolution and tectoni events inferred from the Cuoe core in the middle of Tibetan Plateau显示文摘Based on a multi-proxy investigation into the deep core of the Cuoe Lake in the middle of Tibetan Plateau, a 2.8 Ma paleoclimatic and paleoenvironmental evolution is recon- structed. The result of magnetic stratum indicates that the lake basin was formed at about 2.8 MaBP, while the multi-proxy analyses of lithology, grain size, magnetic susceptibility and geo- chemical elements reveal that there have been three major environmental evolution stages and at least two intensive uplifts of the Tibetan Plateau in the lake basin area, i.e. during 2.8—2.5 MaBP, the lake basin came into being as a result of the disaggregation of the planation surface and rapid rising of the Tibetan Plateau. During 2.5—0.8 MaBP, with gradual uplift of the Tibetan Plateau, the environment of this area was more effectively controlled by the climatic cycle of the alternative glacial-interglacial stages. After 0.8 MaBP, the middle part of the Plateau accelerated its uplift and entered cryoshere. | SHEN Ji1,Lü Houyuan2,WANG Sumin1,CHEN Shiyue1,YANG Xiangdong1,WU Yanhong1 & ZHU Zhaoyu3 1.Nanjing Institute of Geography and Limnology,Chinese Academy of Sciences,Nanjing 210008,China 2.Institute of Geology and Geophysics,Chinese Academy of Sciences,Beijing 100029,China 3.Guangzhou Institute of Geochemistry,Chinese Academy of Sciences,Guangzhou 510640,China Correspondence should be addressed to Shen Ji(email: jishen@niglas.ac.cn) | 2004 | Science China Earth Sciences2004，47，11： | 15 |
| 2 | Periodicity and map for discovery of new ionic liquids显示文摘There is virtually no limit in the number of ionic liquids. How to select proper ones or discover new ones with desirable properties in such a large pool of ionic liquids? It has become a bottleneck in the researches and applications of ionic liquids. Mendeleev’s periodic law states that the properties of the elements vary periodically. Whether the similar regularity exists among ionic or mo-lecular fragments of compounds is an interesting topic. In this work, we attempted to establish a pe-riodicity and draw a “map” of ionic liquids for providing definite guidance to discover, design, and se-lect the proper ionic liquids rather than trial-and-error. If a complete regularity of the system of ionic liquids can be finally established in the future, we are near an epoch in understanding the existing differences and the reasons for the similarity of the ions or molecular fragments. | ZHANG Suojiang, SUN Ning, ZHANG Xiangping & Lü Xingmei Research Laboratory for Green Chemical Engineering and Technology, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080, China Correspondence should be addressed to Zhang Suojiang | 2006 | Science China Chemistry2006，49，2： | 9 |
| 3 | 牛津单髁膝关节置换:长期结果(英文)显示文摘牛津膝置换是使用最广泛的膝关节单髁置换(UKR)。牛津膝在37年前开始应用,拥有一个全匹配的活动衬垫,因而磨损率非常低。牛津膝最主要的使用指征是膝关节前内侧骨关节炎,这种病人至少占所有需要行膝关节置换术患者的50%。由于这一系统的设计特点,传统UKR的反指征,如年龄、活动量、肥胖、髌股关节损害和软骨钙质沉着症等对于牛津膝均不是反指征。与全膝关节置换(TKR)相比,牛津膝提供更快的康复、更好的功能、更大的活动度和更好的术后满意度,发生并发症更少、程度更轻,病残率和死亡率更低。一个持续超过30年的研究显示在90%的病例中,牛津膝为患者终生提供了优或良的临床结果,且不需要翻修。在最近15年,牛津膝通过微创手术入路植入,涉及6000多例使用该入路牛津膝置换的9个研究报道显示,10年生存率约95%。在许多这样的研究中,医生们在拟行膝关节置换的患者中约50%使用了牛津单髁膝置换。 | DW Murray BE Marks L Kontochristos CAF Dodd HG Pandit | 2013 | 中华关节外科杂志(电子版)2013，7，4： | 9 |
| 4 | Intestinal alkaline phosphatase in the colonic mucosa of children with inflammatory bowel disease显示文摘AIM:To investigate intestinal alkaline phosphatase(iAP) in the intestinal mucosa of children with inflammatory bowel disease(IBD).METHODS:Colonic biopsy samples were taken from 15 newly diagnosed IBD patients and from 10 healthy controls.In IBD patients,specimens were obtainedboth from inflamed and non-inflamed areas.The iAP mRNA and protein expression was determined by reverse transcription-polymerase chain reaction and Western blotting analysis,respectively.Tissue localization of iAP and Toll-like receptor(TLR) 4 was investigated by immunofluorescent staining.RESULTS:The iAP protein level in the inflamed mucosa of children with Crohn's disease(CD) and ulcerative colitis(UC) was significantly decreased when compared with controls(both P < 0.05).Similarly,we found a significantly decreased level of iAP protein in the inflamed mucosa in CD compared with non-inflamed mucosa in CD(P < 0.05).In addition,the iAP protein level in inflamed colonic mucosa in patients with UC was decreased compared with non-inflamed mucosa in patients with CD(P < 0.05).iAP protein levels in the non-inflamed mucosa of patients with CD were similar to controls.iAP mRNA expression in inflamed colonic mucosa of children with CD and UC was not significantly different from that in non-inflamed colonic mucosa with CD.Expression of iAP mRNA in patients with noninflamed mucosa and in controls were similar.Co-localization of iAP with TLR4 showed intense staining with a dotted-like pattern.iAP was present in the inflamed and non-inflamed mucosa of patients with CD,UC,and in control biopsy specimens,irrespective of whether it was present in the terminal ileum or in the colon.However,the fluorescent signal of TLR4 was more pronounced in the colon compared with the terminal ileum in all groups studied.CONCLUSION:Lower than normal iAP protein levels in inflamed mucosa of IBD patients may indicate a role for iAP in inflammatory lesions in IBD.Based on our results,administration of exogenous iAP enzyme to patients with the active form of IBD may be a therapeutic option. | Kriszta Molnár dám Vannay Beáta Szebeni Nóra Fanni Bánki Erna Sziksz ron Cseh Hajnalka Gyrffy Péter László Lakatos Mária Papp András Arató Gábor Veres | 2012 | World Journal of Gastroenterology2012，18，25： | 5 |
| 5 | Preparation of Pt/K_2La_2Ti_3O_(10) and its photo-catalytic activity for hydrogen evolution from methanol water solution显示文摘A layered perovskite-type oxide K2La2Ti3O10 was prepared with high-temperature solid-state reaction, and characterized with X-ray diffraction (XRD) and ultraviolet-visible diffuse re-flectance spectroscopy (UV-Vis DRS). Platinum was loaded onto K2La2Ti3O10 as a co-catalyst with different methods. The dispersion of platinum on K2La2Ti3O10 was determined with HOT method. The photocatalytic activity of Pt/K2La2Ti3O10 was studied. This catalyst showed much higher activity in hydrogen evolution reaction than Ni/K2La2Ti3O10. The effects of different amounts of loaded platinum and several preparation methods were evaluated. The best achieved hydrogen evolution rate was 233.88 μmol·h?1 by Pt(2%)/K2La2Ti3O10. A possible band structure and mechanism were discussed based on the results. | CUI Wenquan1,3, LIU Li2, FENG Liangrong1, XU Chenghua1, LI Zijian1, Lü Shaojie1 & QIU Fali1 1. Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China 2. Chemistry Department, Sichuan University of Science & Engineering, Zigong 643033, China 3. Graduate School of the Chinese Academy of Sciences, Beijing 100039, China Correspondence should be addressed to Qiu Fali | 2006 | Science China Chemistry2006，49，2： | 3 |
| 6 | Surgical stress and cytoskeletal changes in lens epithelial cells following manual and femtosecond laser-assisted capsulotomy显示文摘AIM:To study the effect of mechanical stress on the cytoskeleton in lens epithelial cells following conventional phacoemulsification surgery(CPS)and femtosecond laserassisted cataract surgery(FLACS).METHODS:The cytoskeleton of the epithelial cells of the anterior lens capsules(ALC)removed by CPS and FLACS was examined by immunohistochemistry.Expression of the intermediate filament,glial fibrillary acidic protein(GFAP),and glutamine synthetase(GS)immunoreactivity were detected.In order to map the actin network of cells,fluorescently labeled phalloidin was used.The samples were examined using confocal laser scanning microscopy.RESULTS:GFAP expression was visible in a larger number of the epithelial cells after CPS compared to FLACS.In CPS sample’s epithelial cells,GFAP immunoreactivity indicated robust morphological change.Regarding the actin filaments,the presence of tubular elements connecting epithelial cells,regular actin pattern and marked cortical network after CPS were found.Following FLACS,the actin cytoskeleton of the epithelial cells remained densely structured,and the tubular elements were undetectable,however,the above-mentioned regular actin pattern and the marked cortical network were visible.CONCLUSION:The conventional removal of the ALC induces more robust changes of the cytoskeleton of the lens epithelial cells. | ANDrea Krisztina Sükosd Krisztina Szabadfi Edina Szabó-Meleg Beáta Gáspár Pavel Stodulka Gyorgy SétálóJr Róbert Gábriel Miklós Nyitrai Zsolt Biró Hajnalka Abrahám | 2020 | International Journal of Ophthalmology(English edition)2020，13，6： | 2 |
| 7 | Differential c-Fos expression in cholinergic,mono-aminergic,and GABAergic cell groups of the pontomesencephalic tegmentum after paradoxical sleep deprivation and recovery显示文摘 | Maloney KJ Mainville L Jones BE | 1999 | J Neurosci1999，19，8： | 1 |
| 8 | Human pancreatic islets produce and secrete MCP-1/CCL2:relevance in human islet transplantation显示文摘 | PIEMONTI L LEONE BE NANO R | 2002 | Diabetes2002，51，1： | 1 |
| 9 | Communication andcoping as predictors of fertility problem stress:cohort study of 816participants who did not achieve a delivery after 12 months of fertilitytreatment显示文摘 | Schmidt L Holstein BE Christensen U | 2005 | Hum Reprod2005，20，11： | 1 |
| 10 | Dual embryonic origin of the mammalian otic vesicle forming the inner ear显示文摘 | Freyer L Aggarwal V Morrow BE | 2011 | Development2011，138，24： | 1 |
| 11 | Spinal cord and nerve root blood flow in acute double level spinal stenosis显示文摘 | Jespersen SM Christensen K Svenstrup L Lindblad BE Hansen ES Bunger C | 1997 | Spine1997，22，24： | 1 |
| 12 | Reproducibility, fidelity, and discriminant validity of mRNA amplification for microarray analysis from primary hematopoietic ceils 显示文摘 | Li L Roden J Shapiro BE | 2005 | Mol Diagn2005，7，1： | 1 |
| 13 | Fatty fish in the diet of patients with type 2 diabetes: comparison of the metabolic effects of foods rich in n-3 and n-6 fatty acids显示文摘 | Karlstr?m BE J?rvi AE Byberg L | 2011 | Am J Clin Nutr2011，94，1： | 1 |
| 14 | Patch testing for food-associated allergies in orofacial granulomatosis显示文摘 | Fitzpatrick L Healy CM Mccartan BE | 2011 | J Oral PatholMed2011，40，1： | 1 |
| 15 | Value of echography in the diagnosis of acute intersfinal occlusion显示文摘 | Danse EM Van Beers BE Goncette L | 1996 | J Radiol1996，77，12： | 1 |
| 16 | Cystatin C :a po- tential biomarker for pulmonary arterial hypertension 显示文摘 | Fenster BE Lasalvia L Schroeder JD | 2014 | Respirology2014，19，4： | 1 |
| 17 | c-Fos expression in GABAergic,serotonergic,and other neurons of the pontomedullary reticular formation and raphe after paradoxical sleep deprivation and recovery显示文摘 | Maloney KJ Mainville L Jones BE | 2000 | J Neurosci2000，20，12： | 1 |
| 18 | The long term evaluation of periodontal treatment and maintenance in 95 patients 显示文摘 | Becker W Berg L Becker BE | 1984 | Int J Periodontics Restorative Dent1984，4，2： | 1 |
| 19 | Physicochem~cal, structural, and digesti~ihty properties of enzymatic modified plantain and mango starches 显示文摘 | Casarrubias- Castillo M G Hamaker B R Rodriguez-Ambriz S L Be~o-P~rez L A_ | 2012 | Starch/Starke2012，64，4： | 1 |
| 20 | Effects of halothane,enflurane end isoflurane in rat lungs in vitro显示文摘 | Marshall C Lindgren L Marshall BE | 1984 | Anesthesiology1984，60，4： | 1 |
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