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| 1 | Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas. | Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan | 2014 | World Journal of Gastroenterology2014，20，46： | 21 |
| 2 | Duloxetine versus placebo in the treatment of patients with generalized anxiety disorder in China显示文摘背景 Duloxetine 在试图估计功效的美国和 elsewhere.This 学习为概括焦虑混乱(荡者)的治疗被同意, tolerability ,并且在有 GAD.Methods 的中国病人的 duloxetine 的安全这9地点研究与至少中等严重的荡者和 Sheehan 残疾规模( SDS )与 duloxetine 60-120 mg 或与 placebo.Patients 由双窗帘治疗组成了 15 个星期全球工作缺陷总数分数 12 在这研究被包括。在那个点,为 nonresponders ,剂量为留下被增加到 120 mg 主要功效措施是的 8 weeks.The 医院焦虑和消沉规模焦虑 subscale 分数上的端点的从基线的吝啬的变化( HADS --一) .Secondary 功效措施包括了哈密尔顿焦虑等级规模( HAMA ), SDS ,和疼痛 measures.Safety 和 tolerability 是 assessed.Results 基线特征没在这些题目( n=210 )的治疗 groups.Mean 年龄之间显著地不同是 37.6 | WU Wen-yuan WANG Gang Susan G Ball Durisala Desaiah ANG Qiu-qing | 2011 | Chinese Medical Journal2011，，20： | 8 |
| 3 | Effects on reproduction performance of administration of GnRH to early postpartum dairy cows显示文摘 | Nash Jr J G Ball L Olson J D | 1980 | J Anim Sci1980，50，： | 2 |
| 4 | Natural history of intraductal papillary mucinous neoplasia:How much do we really know?显示文摘Information on the natural history of intraductal papillary mucinous neoplasia(IPMN) is currently inadequate due to a lack of carefully orchestrated long-term followup on a large cohort of patients with asymptomatic disease.Based on the available data,one can draw the conclusions that main duct IPMN is commonly associated with malignancy and an aggressive operative stance should be taken with resection being offered to most patients who are suitable operative candidates.In contrast,the majority of branch type IPMN with a diameter of less than 3 cm can be safely followed with routine surveillance imaging provided they lack the high-risk covariates of age,symptomatology,nodularity or wall thickness. | Chad G Ball Thomas J Howard | 2010 | World Journal of Gastrointestinal Surgery2010，2，10： | 2 |
| 5 | Science at atomic scale显示文摘 | Li G | 1992 | Nature1992，355，： | 1 |
| 6 | Effect of atorvastatin on kidney function in chronic kidney disease: a randomised double-blind placebo-controlled trial显示文摘 | Fassett R G Robertson I K Ball M J | 2010 | Atherosclerosis2010，213，1： | 1 |
| 7 | Moisture and suction insanitary landfills in semiarid areas显示文摘 | Blight G E Ball J M Blight J J | 1992 | Journal of EnvironmentalEngineering1992，118，6： | 1 |
| 8 | Adsorption-partitioning uptake of nine low polarity organic chemicals on a natural sorbent 显示文摘 | Xia G Ball W P | 1999 | Environ Sci Technol1999，33，2： | 1 |
| 9 | Conjugating berberine to a multidmg efflux pump inhibitor creates an effective antimicrobial 显示文摘 | BALL A R CASADEI G SAMOSORN S | 2006 | ACS Chem Biol2006，24，9： | 1 |
| 10 | Changes in brain GnRH associated withphotorefractoriness in house sparrows (Passer domesticus) 显示文摘 | Hang T P Ball G F | 1995 | General Comp Endocrinol1995，99，： | 1 |
| 11 | Adsorption-Partitioning Upiake of Nine Low- Polarity Organic Chemicals on a Natural Sorbent 显示文摘 | Xia G Ball W P | 1999 | Environ Sci Teehnol1999，33，： | 1 |
| 12 | Gene rearrangement attenuates expression and lethality of a nonsegmented negative strand RNA virus 显示文摘 | Wertz G W Perepelitsa V P Ball L A | 1998 | Proc Natl Acad Sci1998，95，： | 1 |
| 13 | Continuously tunable single-mode erbium fiber laser显示文摘 | G A Ball W W Morey | 1992 | Opt Lett1992，17，6： | 1 |
| 14 | The efficacy of an automated preparation device for cervical cytology显示文摘 | Hutchinson M L Cassin C M Ball H G 3rd | 1991 | Am J Clin Pathol1991，96，3： | 1 |
| 15 | Nutraceuticals-a pharmaceutical viewpoint:part Ⅱ显示文摘 | HARDY G HARDY I BALL PA | 2003 | Curr Opin Clin Nutr Metab Care2003，6，6： | 1 |
| 16 | Rolling textures of a Cu-20% Nb composite显示文摘 | Raabe D Ball J Gottstein G | 1992 | Scr Metall Mater1992，27，： | 1 |
| 17 | Effect on biopsy technique of the breast imaging reporting and data system (BI-RADS) for nonpalpable mammographic abnormalities显示文摘 | Ball C G Butchart M MacFarlane J K | 2002 | Can J Surg2002，45，4： | 1 |
| 18 | FTIR product study of the reactions CH3O2^ + CH3O2 and CH302 + O3显示文摘 | Tyndall G S Wallington T J and Ball J C | 1998 | J Phys ChemA1998，102，： | 1 |
| 19 | The Stanford Microarray Database:a user's guide array显示文摘 | Gollub J Ball CA Sherlock G | 2006 | Methods Mol Biol2006，338，： | 1 |
| 20 | High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses 显示文摘 | Abd El-Rehim D M Ball G Pinder S E | 2005 | Cancer2005，116，3： | 1 |
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