|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | β内酰胺类抗生素与对非典型病原体有效的抗生素在非重症社区获得性肺炎中的疗效比较:汇总分析显示文摘目的对于社区获得性肺炎,将β内酰胺类抗生素与对非典型病原体有效的抗生素进行全面系统的疗效比较。资料来源Medline、Embase、Cochrane登记注册的对照试验、国际性会议的会议纪录、药品注册机构以及制药公司。评价方法通过总结双盲、随机、对照、单一给药疗法试验,对β内酰胺类抗生素与对非典型病原体有效的抗生素在成人社区获得性肺炎的疗效方面进行比较。主要结局指标是未达到临床治愈或好转。结果18项临床试验共纳入6749例受试者,其中大多数患者有轻至中度社区获得性肺炎。对各种原因引起的社区获得性肺炎治疗失败的相对危险度进行分析,结果显示对非典型病原体有效的抗生素并不优于β内酰胺类抗生素(0.97,95%可信区间0.87~1.07)。对于有特异性非典型病原体感染诊断的患者进行亚组分析,我们发现应用对非典型病原体有效的抗生素治疗军团菌属感染的肺炎患者,其治疗无效率明显的低一些(0.40,0.19~0.85)。而在肺炎支原体(0.60,0.31~1.17)和肺炎衣原体(2.32,0.67~8.03)感染的肺炎患者中二者的疗效相似。结论应用对非典型病原体有效的抗生素治疗由各种原因引起的非重症社区获得性肺炎,而使临床疗效得到提高的证据是不足的。尽管此类抗生素在对稍后介绍的军团菌感染相关性肺炎的治疗方面显示出明显的优势,但已纳入研究范围内的肺炎病例很少是由这种病原体引起的。β内酰胺类制剂应该继续作为成人非重症社ResInfe区获得性肺炎治疗的首选抗生素。 | Graham D Mills Michael R Oehley Bruce Arrol 刘艳(译) 代华平(校) | 2005 | 英国医学杂志中文版2005，8，4： | 2 |
| 2 | Serum paraoxonase after myocardial infarction显示文摘 | Ayub A Mackness MI Arrol S | 1999 | ArteriosclerThmmb vasc Biol1999，19，2： | 1 |
| 3 | Rates and impact of human antibody glycation in vivo 显示文摘 | Goetze AM Liu YD Arroll T | 2012 | Glycobiology2012，22，2： | 1 |
| 4 | Serum paraoxonase after myocardial infarction 显示文摘 | Ayub A Mackness M J Arrol S | 1999 | Arterioscler Thromb Vasc Biol1999，19，1： | 1 |
| 5 | An evidence-based guideline for the management of uterine fibroids显示文摘 | Farquhar C Arroll B Ekeroma A | 2001 | Aust N Z J Obstet Gynaecol2001，41，2： | 1 |
| 6 | Lipids and CVD manage- ment:towards a global consensus 显示文摘 | Ballantyne C Arroll B Shepherd J | 2005 | Eur Heart J2005，26，21： | 1 |
| 7 | Effectiveness of beta lactam antibiotics compared with antibiotics active against atypical pathogens in non-severe community acquired pneumonia:meta-analysis显示文摘 | Oehley M R Arrol B | 2005 | BMJ2005，330，： | 1 |
| 8 | Serum paraoxonase(PON1) 55 and 192 polymorphism and paraoxonase activity and concentration in non-insulin dependent diabetes mellitus显示文摘 | Mackness B Mackness MI Arrol S | 1998 | Atherosclerosis1998，139，： | 1 |
| 9 | Sleep disorders, depression, anxiety and satisfaction with life among young adults: a survey of university students in Auckland, New Zealand显示文摘 | Samaranayake CB Arroll B Femando AT 3rd | 2014 | N Z Med J2014，127，1399： | 1 |
| 10 | Effect of the human serum paraoxonase 55 and 192 genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modification 显示文摘 | Mackness B Mackness MI Arrol S | 1998 | FEBS Lett1998，423，： | 1 |
| 11 | Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein显示文摘 | Mackness MI Arrol S Durrington PN | 1991 | FEBS Lett1991，286，： | 1 |
| 12 | Effect of the molecular polymorphisms of human paraoxonase ( PON1 ) on the rate of hydrolysis of paraoxon显示文摘 | Mackness B Mackness MI ArrolS | 1997 | BrJ Pharmacol1997，112，： | 1 |
| 13 | Antibiotics for upper respiratory tract infections: an overview of Cochrane reviews显示文摘 | Arrol| B | 2005 | Resqir Med2005，99，3： | 1 |
| 14 | Presence of paraoxonase in human interstitial fluid显示文摘 | Mackness MI Mackness B Arrol S | 1997 | FEBS Lett1997，416，3： | 1 |
| 15 | Effect of the human serum paraoxonase 55 and 192genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modification显示文摘 | MACKNESS B MACKNESS M I ARROL S | 1998 | FEBS Lett1998，423，： | 1 |
| 16 | Effect of human serum paraoxonase 55 and 192 genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modification显示文摘 | Mackness B Mackness MI Arrol S | 1998 | FEBS Lett1998，423，1： | 1 |
| 17 | Sleep disorders,depression, anxiety and satisfaction with li{e among young adults a survey of university students in Auck- land, New Zealand显示文摘 | Samaranayake CB Arroll B Fernando AT 3rd | 2014 | N ZMedJ2014，127，1399： | 1 |
| 18 | Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein显示文摘 | MACKNESS M I ARROL S DURRINGTON P N | 1991 | FEBS Lett1991，286，12： | 1 |
| 19 | Lipids and CVD manage- ment,towards a global consensus 显示文摘 | Ballantyne C Arroll B Shepherd J | 2005 | Eur Heart J2005，26，21： | 1 |
| 20 | Eficacy and tolerabil, hy of selective serotonin reuptake inhibitors compared with tricyclic antIdeDressants in depression treated in primary care:systematic review and meta-analysis显示文摘 | MacGillivray S Arroll B | 2003 | BMJ2003，326，7397： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员