|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of nonalcoholic fatty liver disease:An evidence-based clinical practice review显示文摘AIM:To build a consensus among Chilean specialists on the appropriate management of patients with nonalcoholic fatty liver disease(NAFLD)in clinical practice.METHODS:NAFLD has now reached epidemic proportions worldwide.The optimal treatment for NAFLD has not been established due to a lack of evidence-based recommendations.An expert panel of members of the Chilean Gastroenterological Society and the Chilean Hepatology Association conducted a structured analysis of the current literature on NAFLD therapy.The quality of the evidence and the level of recommendations supporting each statement were assessed according to the recommendations of the United States Preventive Services Task Force.A modified three-round Delphi technique was used to reach a consensus among the experts.RESULTS:A group of thirteen experts was established.The survey included 17 open-ended questions that were distributed among the experts,who assessed the articles associated with each question.The levels of agreement achieved by the panel were 93.8%in the first round and 100%in the second and third rounds.The final recommendations support the indication of lifestyle changes,including diet and exercise,for all patients with NAFLD.Proven pharmacological therapies include only vitamin E and pioglitazone,which can be used in nondiabetic patients with biopsy-proven nonalcoholic steatohepatitis(the progressive form of NAFLD),although the long-term safety and efficacy of these therapies have not yet been established.CONCLUSION:Current NAFLD management is rapidly evolving,and new pathophysiology-based therapies are expected to be introduced in the near future.All NAFLD patients should be evaluated using a three-focused approach that considers the risks of liver disease,diabetes and cardiovascular events. | Juan P Arab Roberto Candia Rodrigo Zapata Cristián Mu?oz Juan P Arancibia Jaime Poniachik Alejandro Soza Francisco Fuster Javier Brahm Edgar Sanhueza Jorge Contreras M Carolina Cuellar Marco Arrese Arnoldo Riquelme | 2014 | World Journal of Gastroenterology2014，20，34： | 11 |
| 2 | Therapeutic alternatives for the treatment of type 1 hepatorenal syndrome: A Delphi technique-based consensus显示文摘AIM To propose several alternatives treatment of type 1 hepatorenal syndrome(HRS-1) what is the most severe expression of circulatory dysfunction on patients with portal hypertension.METHODS A group of eleven gastroenterologists and nephrologists performed a structured analysis of available literature.Each expert was designated to review and answer a question.They generated draft statements for evaluation by all the experts.Additional input was obtained from medical community.In order to reach consensus,a modified three-round Delphi technique method was used.According to United States Preventive Services Task Force criteria,the quality of the evidence and level of recommendation supporting each statement was graded.RESULTS Nine questions were formulated.The available evidence was evaluated considering its quality,number of patients included in the studies and the consistency of its results.The generated questions were answered by the expert panel with a high level of agreement.Thus,a therapeutic algorithm was generated.The role of terlipressin and norepinephrine was confirmed as the pharmacologic treatment of choice.On the other hand the use of the combination of octreotide,midodrine and albumin without vasoconstrictors was discouraged.The role of several other options was also evaluated and the available evidence was explored and discussed.Liver transplantation is considered the definitive treatment for HRS-1.The present consensus is an important effort that intends to organize the available strategies based on the available evidence in the literature,the quality of the evidence and the benefits,adverse effects and availability of the therapeutic tools described.CONCLUSION Based on the available evidence the expert panel was able to discriminate the most appropriate therapeutic alternatives for the treatment of HRS-1. | Juan P Arab Juan C Claro Juan P Arancibia Jorge Contreras Fernando Gomez Cristian Munoz Leyla Nazal Eric Roessler Rodrigo Wolff Marco Arrese Carlos Benítez | 2016 | World Journal of Hepatology2016，8，25： | 3 |
| 3 | Noninvasive ventilation during persistent weaning failure:a randomized eontrlled trial显示文摘 | Ferrer M Esquinas A Arancibia F | 2003 | Am J Respir Crit Care Meal2003，168，1： | 1 |
| 4 | Behavior of brain perfusion with SPECT tomography 99mTc ethylene dicysteine (ECD) in alcohol and cocaine dependents during abstinence显示文摘 | Pallavicini Gonzalez J Massardo Vega T Arancibia Soto P | 2002 | Rev Esp Med Nucl2002，21，6： | 1 |
| 5 | Toll - like reeeptors are key participants in innate immune responses 显示文摘 | Arancibia SA Beltr6n CJ Aguirre IM | 2007 | Biol Res2007，40，2： | 1 |
| 6 | Noninvasive ventilation during persistent weaning failure: a randomized controlled trial 显示文摘 | Ferrer M Esqinas A Arancibia F | 2003 | Am J Respir Crit Care Med2003，168，1： | 1 |
| 7 | Noninvasive ventilation during persistent weaning failure:a randomized controlled trial显示文摘 | Ferrer M Esquinas A Arancibia F et aI | 2003 | Am J Respir Crit Care Meal2003，186，1： | 1 |
| 8 | Noninvasive ventilation during persistent weaning failure : a randomized controlled trial 显示文摘 | Ferrer M Esquinas A Arancibia F | 2003 | Am J Respir Crit Care Med2003，168，1： | 1 |
| 9 | Antimicrobial treatment failures in patients with community-acquired pneumonia显示文摘 | Arancibia F Ewig S Martinez JA | 2000 | Am J Respir Crit Care Med2000，162，1： | 1 |
| 10 | Antimicrobial treatment failures in patients with community-acquired pneumonia:causes and prognostic implications显示文摘 | Arancibia F Ewig S Martinez JA | 2000 | Am J Respir Crit Care Med2000，162，： | 1 |
| 11 | Long-term ehanges in the mean trophie level of Central Chile fisherylandings显示文摘 | ARANCIBIA H NEIRA S | 2005 | Scientia Marina2005，69，2： | 1 |
| 12 | Pharmacokinetics of prednisolone in man during acute and chronic exposure to high altitude显示文摘 | Arancibia A Gai MN Chavez J | 2005 | Int J Clin Pharm Ther2005，43，2： | 1 |
| 13 | Effects of chitosan particles in periodontal pathogens and gingival fibroblasts显示文摘 | Arancibia R Maturana C Silva D | 2013 | J Dent Res2013，92，74： | 1 |
| 14 | Noninvasive ventilation during persistent weaning failure: a randomized controlled trial显示文摘 | Ferrer M Esquinas A Arancibia F | 2003 | Am J Respir Crit Care Med2003，168，1： | 1 |
| 15 | Pharmaeokinetics of lithium in healthy volunteers after exposure to high altitude 显示文摘 | Arancibia A Paulos C Chavez J | 2003 | Int J Clin Pharmacol Ther2003，41，5： | 1 |
| 16 | Using Ecoteehnology to address water quality and wetland habitat loss problems in the Mississippi basin : a hierarchical approach 显示文摘 | DAY J W ARANCIBIA Y A MITSCH W J | 2003 | Biotechnology Advances2003，22，12： | 1 |
| 17 | Acute cholangitis caused by choledochalithiasis: traditional surgery or endoscopic biliary drainage 显示文摘 | ANSELMI M SAL GADO J ARANCIBIA A | 2001 | Rev Med Chil2001，129，7： | 1 |
| 18 | A neural - networks - based adaptive disturbance rejection meth- od and its application to the control of hard disk drives 显示文摘 | LEVIN J PEREZ - ARANCIBIA N O IOANNOU P A | 2009 | IEEE Transactions on Magnetics Part 12009，45，5： | 1 |
| 19 | Phamacokinetics of acetazolamide in healthy volunteers after short and long-term exposure to high altitude显示文摘 | RITSCHEL W A PAULOS C ARANCIBIA A | 1998 | J Clin Pharmacol1998，38，6： | 1 |
| 20 | Microbial airway colonization is associated with noninvasive ventilation failure in exacerbation of chronic obstructive pulmonary disease显示文摘 | Ferrer M Ioanas M Arancibia F | 2005 | Crit Care Med2005，33，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员